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D1BIM2 (D1BIM2_SANKS) Unreviewed, UniProtKB/TrEMBL

Last modified March 19, 2014. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase RuleBase RU004136

EC=6.3.2.10 RuleBase RU004136
Gene names
Ordered Locus Names:Sked_22840 EMBL ACZ22199.1
OrganismSanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74) [Complete proteome] [HAMAP] EMBL ACZ22199.1
Taxonomic identifier446469 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeSanguibacteraceaeSanguibacter

Protein attributes

Sequence length464 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein By similarity.

Catalytic activity

ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine.

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the MurCDEF family. RuleBase RU003630

Sequences

Sequence LengthMass (Da)Tools
D1BIM2 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: 1F2A4BC78AFF2AB1

FASTA46447,650
        10         20         30         40         50         60 
MIDLTAAEVA DLTGGTLAAP HTTRVHGPTV VDSRKVSAGA LFVALVGESS DGHDHAAGAV 

        70         80         90        100        110        120 
ADGAALVLAS RELDGLPCVV VDDVTRALGL VAAEHLRRLR ASGPLQVAAV TGSVGKTTTK 

       130        140        150        160        170        180 
DLLGHVLSES GPTVMPRASF NNEIGLPLTV LEAGPETRYL VLEMGASAPG DLTYLTGIAP 

       190        200        210        220        230        240 
PDVSIVLAVG AAHLGGFGGL DGVARAKSEI VTGLRPEGVA VLNADDHRVV AMRDLAPSRV 

       250        260        270        280        290        300 
VTFGTVRDAG VRAHRVSVDR LGRVSCQVVV GERTADLSLR LVGEHHLTNA LAALTAAVEL 

       310        320        330        340        350        360 
GVDLDTAAAL VSSVDAASPH RMAVTERPDG VTVIDDSYNA NPDSMRAALK ALAVVAGRDR 

       370        380        390        400        410        420 
RSVAVLGEML ELGPDSRDQH DEIGRLVVRL NIKLLVVVGA GASGLADGAT QEGSWGEEVV 

       430        440        450        460 
EVEDVPAAER FLAEELRSGD VVLVKSSNGS GLWRLGDALT AVTS 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001819 Genomic DNA. Translation: ACZ22199.1.
RefSeqYP_003315033.1. NC_013521.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ22199; ACZ22199; Sked_22840.
GeneID8633919.
KEGGske:Sked_22840.
PATRIC32393020. VBISanKed123513_2253.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000268120.
KOK01929.
OMAANHLGEI.

Enzyme and pathway databases

BioCycSKED446469:GHD3-2280-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.40.1190.10. 1 hit.
3.40.1390.10. 1 hit.
3.90.190.20. 1 hit.
InterProIPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR005863. UDP-N-AcMur-pentapeptide_synth.
[Graphical view]
PANTHERPTHR23135:SF3. PTHR23135:SF3. 1 hit.
PfamPF01225. Mur_ligase. 1 hit.
PF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
SUPFAMSSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
SSF63418. SSF63418. 1 hit.
TIGRFAMsTIGR01143. murF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD1BIM2_SANKS
AccessionPrimary (citable) accession number: D1BIM2
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: March 19, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)