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D1BEV7 (D1BEV7_SANKS) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylformylglycinamidine synthase 1 HAMAP-Rule MF_00421

EC=6.3.5.3 HAMAP-Rule MF_00421
Alternative name(s):
Phosphoribosylformylglycinamidine synthase I HAMAP-Rule MF_00421
Gene names
Name:purQ HAMAP-Rule MF_00421
Ordered Locus Names:Sked_35050 EMBL ACZ23393.1
OrganismSanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74) [Complete proteome] [HAMAP] EMBL ACZ23393.1
Taxonomic identifier446469 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeSanguibacteraceaeSanguibacter

Protein attributes

Sequence length238 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate. HAMAP-Rule MF_00421 SAAS SAAS010075

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2. HAMAP-Rule MF_00421 SAAS SAAS010075

Subunit structure

Heterodimer of two subunits, PurQ and PurL By similarity. HAMAP-Rule MF_00421 SAAS SAAS010075

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00421 SAAS SAAS010075.

Sequence similarities

Contains 1 glutamine amidotransferase type-1 domain. HAMAP-Rule MF_00421

Contains glutamine amidotransferase type-1 domain. SAAS SAAS010075

Contains glutamine amidotransferase type-domain. SAAS SAAS010075

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site921Nucleophile By similarity HAMAP-Rule MF_00421
Active site2011 By similarity HAMAP-Rule MF_00421
Active site2031 By similarity HAMAP-Rule MF_00421

Sequences

Sequence LengthMass (Da)Tools
D1BEV7 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: BD8DB58913F80F73

FASTA23824,941
        10         20         30         40         50         60 
MSDVLTGARI GVITFPGTLD DRDAARAVRI AGATAVPLWH ADADLHGVDA VVLPGGFSYG 

        70         80         90        100        110        120 
DYLRAGAISR FAPVMDVLVD AAKGGLPVLG ICNGFQILTE SHLLPGSMIK NDSLSFLCRE 

       130        140        150        160        170        180 
QRLTVENADT AWTRGFRAGQ EITIPLKNQD GQFVADEHTL DELEGEGRVV FRYAGENPNG 

       190        200        210        220        230 
SRRGIAGITN AAGNVVGLMP HPEHAVEVGF GTAAEAGPRA GTDGLTFFTS VLGTLVTA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001819 Genomic DNA. Translation: ACZ23393.1.
RefSeqYP_003316227.1. NC_013521.1.

3D structure databases

ProteinModelPortalD1BEV7.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ23393; ACZ23393; Sked_35050.
GeneID8635138.
KEGGske:Sked_35050.
PATRIC32395493. VBISanKed123513_3470.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000238240.
KOK01952.
OMADGLGFFT.

Enzyme and pathway databases

BioCycSKED446469:GHD3-3499-MONOMER.
UniPathwayUPA00074; UER00128.

Family and domain databases

HAMAPMF_00421. PurQ.
InterProIPR017926. GATASE.
IPR010075. PRibForGlyAmidine_synth_I.
[Graphical view]
PIRSFPIRSF001586. FGAM_synth_I. 1 hit.
TIGRFAMsTIGR01737. FGAM_synth_I. 1 hit.
PROSITEPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD1BEV7_SANKS
AccessionPrimary (citable) accession number: D1BEV7
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: February 19, 2014
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)