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Protein

Thymidine kinase

Gene

Sked_12890

Organism
Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + thymidine = ADP + thymidine 5'-phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei94Proton acceptorUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseUniRule annotationImported, Transferase
Biological processDNA synthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSKED446469:GHD3-1277-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Thymidine kinaseUniRule annotation (EC:2.7.1.21UniRule annotation)
Gene namesi
Ordered Locus Names:Sked_12890Imported
OrganismiSanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)Imported
Taxonomic identifieri446469 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaMicrococcalesSanguibacteraceaeSanguibacter
Proteomesi
  • UP000000322 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi446469.Sked_12890.

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107W53. Bacteria.
COG1435. LUCA.
HOGENOMiHOG000076391.
KOiK00857.
OMAiRATHNAR.
OrthoDBiPOG091H0659.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
PANTHERiPTHR11441. PTHR11441. 1 hit.
PfamiView protein in Pfam
PF00265. TK. 1 hit.
PIRSFiPIRSF035805. TK_cell. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.

Sequencei

Sequence statusi: Complete.

D1BEF3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKLYFRYGA MNSGKSTALL QAAYNYEERG HQVLLAKPGI DTKAGRAIQS
60 70 80 90 100
RLGFDRDVDF MVGEGQDAYA LFQQHRAHVQ TESGRDVSCL LVDESQFLSA
110 120 130 140 150
GQVNDLLRIA TLDSIPVICY GIRTDFQTAA FPGSRRLLEI AHSLEELKTI
160 170 180 190 200
CRCGRKAIFN ARSVDGVFTF DGAQVAIDGV EVGYESLCAA CYLRESGGHL

TR
Length:202
Mass (Da):22,208
Last modified:January 19, 2010 - v1
Checksum:iEC1BAD97FE56F3EC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001819 Genomic DNA. Translation: ACZ21231.1.
RefSeqiWP_012866300.1. NC_013521.1.

Genome annotation databases

EnsemblBacteriaiACZ21231; ACZ21231; Sked_12890.
KEGGiske:Sked_12890.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD1BEF3_SANKS
AccessioniPrimary (citable) accession number: D1BEF3
Entry historyiIntegrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: July 5, 2017
This is version 49 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported