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D1B5M1 (D1B5M1_THEAS) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate--tRNA ligase HAMAP-Rule MF_00022
EC=6.1.1.17 HAMAP-Rule MF_00022
Alternative name(s):
Glutamyl-tRNA synthetase HAMAP-Rule MF_00022
Gene names
Name:gltX HAMAP-Rule MF_00022
Ordered Locus Names:Taci_1080
OrganismThermanaerovibrio acidaminovorans (strain ATCC 49978 / DSM 6589 / Su883) (Selenomonas acidaminovorans) [Reference proteome] [HAMAP] EMBL ACZ19312.1
Taxonomic identifier525903 [NCBI]
Taxonomic lineageBacteria › Synergistetes › Synergistia › Synergistales › Synergistaceae › Thermanaerovibrio ›

Protein attributes

Sequence length445 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) By similarity. HAMAP-Rule MF_00022

Catalytic activity

ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu). HAMAP-Rule MF_00022

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00022

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00022.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. HAMAP-Rule MF_00022 RuleBase RU003489

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Motif11 – 2111"HIGH" region By similarity HAMAP-Rule MF_00022
Motif217 – 2215"KMSKS" region By similarity HAMAP-Rule MF_00022

Sites

Binding site2201ATP By similarity HAMAP-Rule MF_00022

Sequences

Sequence LengthMass (Da)Tools
D1B5M1 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: 3BF1814709AC0CAD

FASTA44550,593
        10         20         30         40         50         60 
MTEEVRVRFA PSPTGALHIG GAHTALFNWL WAKRTGGKFV LRIEDTDRER STAEYEKTIL 

        70         80         90        100        110        120 
EGLKWLGLDW DEGPDVGGPY GPYRQSERLD TYGRYAEELI EKGLAYREDG AVLFRIPTGE 

       130        140        150        160        170        180 
KVEFNDAVYG PISVMSDHVS VNKDGSIKDM VIIKSDGMPT YNYAVVVDDH CMGINWVIRG 

       190        200        210        220        230        240 
EDHVINTPKQ ILLYRALGWQ VPNFAHLPMI LGKDKKKLSK RHGATSVFEY HGLGYIPEGV 

       250        260        270        280        290        300 
FNFLALLGWS PGADREIITR HEAAKVFDIT KVTKRAAVFD MDKLNHVNQE HLKRLDPMER 

       310        320        330        340        350        360 
LRLVRPFWIE MGLDPSGHGE EYLARTVTLL TSRGKTTREL AEYTDYFVDF RCVLDRYDGS 

       370        380        390        400        410        420 
DLTEETKARL RPFFQEMLRC EPWSASAMEA LARSFGESNA VSLKDVAMPL RFVLSGRRVS 

       430        440 
PGVFEIAELL GPEECRRRLS HFGLL

« Hide

References

[1]"Complete genome sequence of Thermanaerovibrio acidaminovorans type strain (Su883)."
Chovatia M., Sikorski J., Schroder M., Lapidus A., Nolan M., Tice H., Glavina Del Rio T., Copeland A., Cheng J.F., Lucas S., Chen F., Bruce D., Goodwin L., Pitluck S., Ivanova N., Mavromatis K., Ovchinnikova G., Pati A. expand/collapse author list , Chen A., Palaniappan K., Land M., Hauser L., Chang Y.J., Jeffries C.D., Chain P., Saunders E., Detter J.C., Brettin T., Rohde M., Goker M., Spring S., Bristow J., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.P., Eisen J.A.
Stand. Genomic Sci. 1:254-261(2009)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49978 / DSM 6589 / Su883.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001818 Genomic DNA. Translation: ACZ19312.1.
RefSeqYP_003317594.1. NC_013522.1.

3D structure databases

ProteinModelPortalD1B5M1.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ19312; ACZ19312; Taci_1080.
GeneID8630928.
KEGGtai:Taci_1080.
PATRIC32493506. VBITheAci125881_1079.

Phylogenomic databases

HOGENOMHOG000252720.
KOK01885.
OMAFKISEQE.

Enzyme and pathway databases

BioCycTACI525903:GH4K-1119-MONOMER.

Family and domain databases

Gene3D1.10.10.350. 1 hit.
1.10.1160.10. 1 hit.
3.40.50.620. 2 hits.
HAMAPMF_00022_B. Glu_tRNA_synth_B.
InterProIPR008925. aa-tRNA-synth_I_codon-bd.
IPR020751. aa-tRNA-synth_I_codon-bd_sub2.
IPR001412. aa-tRNA-synth_I_CS.
IPR004527. Glu-tRNA-ligase_Ib_bac/mito.
IPR000924. Glu/Gln-tRNA-synth_Ib.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERPTHR10119. PTHR10119. 1 hit.
PTHR10119:SF1. PTHR10119:SF1. 1 hit.
PfamPF00749. tRNA-synt_1c. 2 hits.
[Graphical view]
PRINTSPR00987. TRNASYNTHGLU.
SUPFAMSSF48163. tRNA-synt_bind. 1 hit.
TIGRFAMsTIGR00464. gltX_bact. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD1B5M1_THEAS
AccessionPrimary (citable) accession number: D1B5M1
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: May 29, 2013
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info