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D1B1Z3

- D1B1Z3_SULD5

UniProt

D1B1Z3 - D1B1Z3_SULD5

Protein
Submitted name:

Isocitrate dehydrogenase, NADP-dependent

Gene

Sdel_1089

Organism
Sulfurospirillum deleyianum (strain ATCC 51133 / DSM 6946 / 5175)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (19 Jan 2010)
      Previous versions | rss
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    Functioni

    Cofactori

    Binds 1 magnesium or manganese ion per subunit.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei147 – 1471Substrate
    Sitei257 – 2571Critical for catalysisUniRule annotation
    Metal bindingi352 – 3521Magnesium or manganeseUniRule annotation
    Sitei422 – 4221Critical for catalysisUniRule annotation
    Binding sitei550 – 5501SubstrateUniRule annotation
    Metal bindingi551 – 5511Magnesium or manganeseUniRule annotation
    Metal bindingi555 – 5551Magnesium or manganeseUniRule annotation

    GO - Molecular functioni

    1. isocitrate dehydrogenase (NADP+) activity Source: UniProtKB-EC
    2. metal ion binding Source: UniProtKB-KW

    GO - Biological processi

    1. tricarboxylic acid cycle Source: InterPro

    Keywords - Molecular functioni

    OxidoreductaseImported

    Keywords - Ligandi

    MagnesiumUniRule annotation, Metal-bindingUniRule annotation

    Enzyme and pathway databases

    BioCyciSDEL525898:GHVA-1118-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Isocitrate dehydrogenase, NADP-dependentImported (EC:1.1.1.42Imported)
    Gene namesi
    Ordered Locus Names:Sdel_1089Imported
    OrganismiSulfurospirillum deleyianum (strain ATCC 51133 / DSM 6946 / 5175)Imported
    Taxonomic identifieri525898 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeSulfurospirillum
    ProteomesiUP000002222: Chromosome

    Structurei

    3D structure databases

    ProteinModelPortaliD1B1Z3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni134 – 1418Substrate binding

    Phylogenomic databases

    HOGENOMiHOG000240860.
    KOiK00031.
    OMAiEEQRIGD.
    OrthoDBiEOG6DVJPP.

    Family and domain databases

    Gene3Di3.40.718.10. 3 hits.
    InterProiIPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view]
    PfamiPF03971. IDH. 1 hit.
    [Graphical view]
    PIRSFiPIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsiTIGR00178. monomer_idh. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D1B1Z3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAHTPHKIIY TQVDEAPALA TYSLLPIIKA FVKRSSIKIE TRDISLSGRI    50
    LAHFSDYLTN EQRVNDDLAY LGTLANTPEA NIIKLPNISA SLPQLNAAIK 100
    ELQDKGYLIP SYPENPANEK EQEIKARYAK VLGSAVNPVL REGNSDRRAP 150
    LCVKEYVRKN PHRMGEWHQN SRSHVAYMHE GDFYGNEKSI TMDKATTLRI 200
    ELLSSEGKTT VLKEKLELLE GEIIDGTYMS ASKLAQFYET QMEEAKAQNL 250
    LLSLHLKATM MKVSDPIMFG YAVKTYFKEV FEKYAATFER LGVNANNGLG 300
    DVYAKIATLP EREKNAIEAD IEACYTKRAS LAMVNSDKGI TNLHVPSDVI 350
    IDASMPACIR ESGKMWGKDG ALHETKALIP DRAYARIYEE TMNFCRQNGA 400
    LDPKTMGSVP NVGLMAQKAE EYGSHDKTFE IPYAGVVRMV ESENGAVLME 450
    HRVEKGDIYR ACQAKDAPIR DWVKLAISRA RLSQTPAIFW LDDKRAHDAQ 500
    MIKKVEHYLK AYDLSGLDIK IMSPEDAIKL SLERIVKGLD TIAVTGNVLR 550
    DYLTDLFPIL EVGTSAKMLS IVPLMKGGGL FETGAGGSAP KHVQQFVEEN 600
    HLRWDSLGEF MALSASLEHL STVMGNKQAA ILAKTLDSAT GKVLDEKKSP 650
    SPKVGELDNR GSHFYLALYW AEALSQQDDD ENLAIAFQPL AEALRVNEKT 700
    IVEELNSVQG KRVDLGGYYK LDVEKVNKAM RPSPTFNHAL EIFNA 745
    Length:745
    Mass (Da):82,954
    Last modified:January 19, 2010 - v1
    Checksum:i5ED66FBE19E81145
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001816 Genomic DNA. Translation: ACZ12113.1.
    RefSeqiWP_012856871.1. NC_013512.1.
    YP_003304148.1. NC_013512.1.

    Genome annotation databases

    EnsemblBacteriaiACZ12113; ACZ12113; Sdel_1089.
    GeneIDi8592627.
    KEGGisdl:Sdel_1089.
    PATRICi32482965. VBISulDel109514_1106.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001816 Genomic DNA. Translation: ACZ12113.1 .
    RefSeqi WP_012856871.1. NC_013512.1.
    YP_003304148.1. NC_013512.1.

    3D structure databases

    ProteinModelPortali D1B1Z3.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACZ12113 ; ACZ12113 ; Sdel_1089 .
    GeneIDi 8592627.
    KEGGi sdl:Sdel_1089.
    PATRICi 32482965. VBISulDel109514_1106.

    Phylogenomic databases

    HOGENOMi HOG000240860.
    KOi K00031.
    OMAi EEQRIGD.
    OrthoDBi EOG6DVJPP.

    Enzyme and pathway databases

    BioCyci SDEL525898:GHVA-1118-MONOMER.

    Family and domain databases

    Gene3Di 3.40.718.10. 3 hits.
    InterProi IPR004436. Isocitrate_DH_NADP_mono.
    IPR024084. IsoPropMal-DH-like_dom.
    [Graphical view ]
    Pfami PF03971. IDH. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF009407. IDH_monmr. 1 hit.
    TIGRFAMsi TIGR00178. monomer_idh. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 51133 / DSM 6946 / 5175Imported.

    Entry informationi

    Entry nameiD1B1Z3_SULD5
    AccessioniPrimary (citable) accession number: D1B1Z3
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 19, 2010
    Last sequence update: January 19, 2010
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3