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D1B1V5 (D1B1V5_SULD5) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Sdel_1050 EMBL ACZ12075.1
OrganismSulfurospirillum deleyianum (strain ATCC 51133 / DSM 6946 / 5175) [Complete proteome] [HAMAP] EMBL ACZ12075.1
Taxonomic identifier525898 [NCBI]
Taxonomic lineageBacteriaProteobacteriaEpsilonproteobacteriaCampylobacteralesCampylobacteraceaeSulfurospirillum

Protein attributes

Sequence length344 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain133 – 327195ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding160 – 21152ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2831Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2951Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2951Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2971Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D1B1V5 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: 6E7C9A0A46123D99

FASTA34438,978
        10         20         30         40         50         60 
MKIAVLFGAQ SFEHEISVVS AIALKKVLKS EIVYIFCDYE RNFYLIPTDK ITSKRFSSGE 

        70         80         90        100        110        120 
YKKDKALHVK QGGFYAKKML GEEQISFDVM INLVHGRDGE DGKLSALLDF FGIPYIGPRM 

       130        140        150        160        170        180 
EACSISYNKL FTKLYAKEVG VNVLPYQLLH KGSNEAISIA YPFIVKPLRL GSSIGIGIVK 

       190        200        210        220        230        240 
EEKELAYALD VAFEFDDTVL IEPFISGVKE YNLAGCKTDS FTFSIIEEPQ KEAFLDFDKK 

       250        260        270        280        290        300 
YLDFSRTKRV NEASLEVTLE KEIQTSFIKL YDPLFLGALI RCDFFVIDGV VYLNEINPVP 

       310        320        330        340 
GSMANYLFDD FDGVIKRLVN YLPHTTTVTK EYRYINSIQA AKGK 

« Hide

References

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001816 Genomic DNA. Translation: ACZ12075.1.
RefSeqYP_003304110.1. NC_013512.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ12075; ACZ12075; Sdel_1050.
GeneID8592588.
KEGGsdl:Sdel_1050.
PATRIC32482885. VBISulDel109514_1066.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000102494.
KOK01921.
OMAYVGCDIP.
OrthoDBEOG6ND0KB.

Enzyme and pathway databases

BioCycSDEL525898:GHVA-1079-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 1 hit.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD1B1V5_SULD5
AccessionPrimary (citable) accession number: D1B1V5
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: June 11, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)