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D1AKX9 (D1AKX9_SEBTE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
D-alanine--D-alanine ligase HAMAP-Rule MF_00047

EC=6.3.2.4 HAMAP-Rule MF_00047
Alternative name(s):
D-Ala-D-Ala ligase HAMAP-Rule MF_00047
D-alanylalanine synthetase HAMAP-Rule MF_00047
Gene names
Name:ddl HAMAP-Rule MF_00047
Ordered Locus Names:Sterm_0260 EMBL ACZ07145.1
OrganismSebaldella termitidis (strain ATCC 33386 / NCTC 11300) [Complete proteome] [HAMAP] EMBL ACZ07145.1
Taxonomic identifier526218 [NCBI]
Taxonomic lineageBacteriaFusobacteriaFusobacterialesLeptotrichiaceaeSebaldella

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Catalytic activity

ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. HAMAP-Rule MF_00047 SAAS SAAS011095

Cofactor

Binds 2 magnesium or manganese ions per subunit By similarity. HAMAP-Rule MF_00047 SAAS SAAS011095

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP-Rule MF_00047 SAAS SAAS011095

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00047 SAAS SAAS011095.

Sequence similarities

Belongs to the D-alanine--D-alanine ligase family. HAMAP-Rule MF_00047

Contains 1 ATP-grasp domain. HAMAP-Rule MF_00047

Contains ATP-grasp domain. SAAS SAAS011095

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain102 – 298197ATP-grasp By similarity HAMAP-Rule MF_00047
Nucleotide binding130 – 18556ATP By similarity HAMAP-Rule MF_00047

Sites

Metal binding2531Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2651Magnesium or manganese 1 By similarity HAMAP-Rule MF_00047
Metal binding2651Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047
Metal binding2671Magnesium or manganese 2 By similarity HAMAP-Rule MF_00047

Sequences

Sequence LengthMass (Da)Tools
D1AKX9 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: FC5A0135F03384D4

FASTA30534,090
        10         20         30         40         50         60 
MSKLKIGVVR GGISSEREVS LKSGEGIIRE LNKDKYDVKD IVLNDKNDIF TSLDGVDFVF 

        70         80         90        100        110        120 
LGLHGKFGED GKIQAILETM DIPYTGCGVL ASSLCMDKDI TKHIMRSYGV RTAKWISVRE 

       130        140        150        160        170        180 
GEECDYSEAA AYLGEDIIAK PNSGGSSVGV HFIKNEQEFY EALKDIFTID KEVMIEEVLR 

       190        200        210        220        230        240 
GVEISVPIID GKVYPTLCIE PKAGTFFDYA SKYEVGGADE YVVEFEKELQ DEINELTKTA 

       250        260        270        280        290        300 
YHAVKCEGYA RIDFMLKDNK PYLMEINTLP GMTMTSLVPK SLKHLGVSYS ELLDKLIEVS 


LKIKR 

« Hide

References

[1]"The complete chromosome of Sebaldella termitidis ATCC 33386."
US DOE Joint Genome Institute (JGI-PGF)
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Mikhailova N., Sims D., Meincke L., Brettin T., Detter J.C., Han C. expand/collapse author list , Larimer F., Land M., Hauser L., Markowitz V., Cheng J.F., Hugenholtz P., Woyke T., Wu D., Eisen J.A.
Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 33386 / NCTC 11300.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001739 Genomic DNA. Translation: ACZ07145.1.
RefSeqYP_003307076.1. NC_013517.1.

3D structure databases

ProteinModelPortalD1AKX9.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACZ07145; ACZ07145; Sterm_0260.
GeneID8595756.
KEGGstr:Sterm_0260.
PATRIC32404418. VBISebTer81212_0265.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000011592.
KOK01921.
OMAANDTQYR.
OrthoDBEOG6ND0KB.

Enzyme and pathway databases

BioCycSTER526218:GHLD-266-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.30.1490.20. 1 hit.
3.30.470.20. 2 hits.
3.40.50.20. 1 hit.
HAMAPMF_00047. Dala_Dala_lig.
InterProIPR011761. ATP-grasp.
IPR013815. ATP_grasp_subdomain_1.
IPR013816. ATP_grasp_subdomain_2.
IPR000291. D-Ala_lig_Van_CS.
IPR005905. D_ala_D_ala.
IPR011095. Dala_Dala_lig_C.
IPR011127. Dala_Dala_lig_N.
IPR016185. PreATP-grasp_dom.
[Graphical view]
PANTHERPTHR23132. PTHR23132. 1 hit.
PfamPF07478. Dala_Dala_lig_C. 1 hit.
PF01820. Dala_Dala_lig_N. 2 hits.
[Graphical view]
SUPFAMSSF52440. SSF52440. 1 hit.
TIGRFAMsTIGR01205. D_ala_D_alaTIGR. 1 hit.
PROSITEPS50975. ATP_GRASP. 1 hit.
PS00843. DALA_DALA_LIGASE_1. 1 hit.
PS00844. DALA_DALA_LIGASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD1AKX9_SEBTE
AccessionPrimary (citable) accession number: D1AKX9
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: June 11, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)