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D1ACM7

- D1ACM7_THECD

UniProt

D1ACM7 - D1ACM7_THECD

Protein
Submitted name:

UvrD/REP helicase

Gene

Tcur_3753

Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 37 (01 Oct 2014)
      Sequence version 1 (19 Jan 2010)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + H2O = ADP + phosphate.SAAS annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. ATP-dependent DNA helicase activity Source: InterPro
    3. DNA binding Source: UniProtKB-KW
    4. exonuclease activity Source: UniProtKB-KW

    GO - Biological processi

    1. DNA repair Source: UniProtKB-KW

    Keywords - Molecular functioni

    ExonucleaseSAAS annotation, HelicaseSAAS annotationImported, Hydrolase, Nuclease

    Keywords - Biological processi

    DNA damage, DNA repairSAAS annotation

    Keywords - Ligandi

    ATP-binding, DNA-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciTCUR471852:GHHD-3816-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    UvrD/REP helicaseImported
    Gene namesi
    Ordered Locus Names:Tcur_3753Imported
    OrganismiThermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)Imported
    Taxonomic identifieri471852 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptosporangineaeThermomonosporaceaeThermomonospora
    ProteomesiUP000001918: Chromosome

    Family & Domainsi

    Sequence similaritiesi

    Contains uvrD-like helicase ATP-binding domain.SAAS annotation
    Contains uvrD-like helicase C-terminal domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000247959.
    KOiK03657.
    OMAiTAVGDPC.
    OrthoDBiEOG6S7XR2.

    Family and domain databases

    Gene3Di3.40.50.300. 5 hits.
    InterProiIPR014017. DNA_helicase_UvrD-like_C.
    IPR000212. DNA_helicase_UvrD/REP.
    IPR027417. P-loop_NTPase.
    IPR011335. Restrct_endonuc-II-like.
    IPR014016. UvrD-like_ATP-bd.
    [Graphical view]
    PANTHERiPTHR11070. PTHR11070. 1 hit.
    PfamiPF00580. UvrD-helicase. 1 hit.
    PF13361. UvrD_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 3 hits.
    SSF52980. SSF52980. 1 hit.
    PROSITEiPS51198. UVRD_HELICASE_ATP_BIND. 1 hit.
    PS51217. UVRD_HELICASE_CTER. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D1ACM7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MITPVELARL LELPEPTPEQ ARVISAPLAP MAVIAGAGSG KSETMAARVV     50
    WLVANGLVRP ERVLGLTFTR KAAGELATRI RRRLDQLRDR LPQDELDRLG 100
    GEAALDGEPA VSTYHSYAAR LFGDHALRAA LEPTMRLISP AMAWQLAARV 150
    VDDYDGAMDG IDWRPDTVVR AVLDLSGELA EHLRTPEDVR EIGRRLRAQF 200
    DALPGRRGAA KNVLATQEIR ERLLPLVEAY QRAKIEREVL DYGDQVALAA 250
    RIARDHPDVG MIERSRYAVV LLDEYQDTSH AQLVLLTSLF GGGHPVTAVG 300
    DPCQSIYGWR GAGSGNLTGF PEDFPLAPAV PSRVAAVPPP RPGRRPPRHA 350
    RPAPTATLSI SWRNGERILE VAARIQQGLR ADTANVPRLR PGEGRRGRGR 400
    VECALLPTVT AEAEHIAERI RRLRAADPEL APDGLPWDEG PLKYSHIAVL 450
    VRRRSQIPPL RKALEERDIP VEVVGLGGLL TVPEVQDVVA TLRVVHDPTA 500
    GASLARLLTG PRWRIGPRDL VALGRRARRL ASENTRDITP PPDASELRPE 550
    PAANAEETDP LRQVVIELTQ ETGSLVDALD DLGDPSAYSP EGLARLRRLA 600
    AELRTLRSQV GLPLPDLVAE VERTLGLDIE VAARSGLDPA GARADLDAFI 650
    ETAASFAEES ENPTLGAFLA YLKAAESEEF GLPAGRVSES DSVKLLTVHA 700
    AKGLEWPVVV VPGLCYLPSG SGRPVKGSIF PSPPQQSTRW TDNPRLLPFE 750
    LRGDYEKGNL PRLNGLTKAD LDRFKDECAD RDLREERRLA YVAVTRASHL 800
    LIATGHRWGA TARPLHPSPF LEEIRQACET GAGRVVSWAD PPEEGAANPL 850
    QAEAEPGRWP ATPEGRRYAA IVEGAEMVRD AMVGRIAPWA GDDGLTEADR 900
    RRMTAWARDV ELLLAERDRG RGGDVLQVEL PAKLTVSTLV ALSRDPQEVA 950
    RSIRRPMPRP PAPYARRGTA FHRWLESRWG QQRLLDPDEL PGAADEGAAD 1000
    DSMLTELQRR FEESEWASRR PLDIEVTFET VLGDRVLRGR MDAVFTAPDG 1050
    GYEVVDWKTG RPPADEDFRH AAVQLAAYRL AWADLAGVPL EKVSAAFHYV 1100
    RYNRTIRPAD LLDRAGLTAL LENIRPID 1128
    Length:1,128
    Mass (Da):123,729
    Last modified:January 19, 2010 - v1
    Checksum:iB90C8BE20D7DCE7B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001738 Genomic DNA. Translation: ACY99286.1.
    RefSeqiWP_012854070.1. NC_013510.1.
    YP_003301324.1. NC_013510.1.

    Genome annotation databases

    EnsemblBacteriaiACY99286; ACY99286; Tcur_3753.
    GeneIDi8605106.
    KEGGitcu:Tcur_3753.
    PATRICi32517274. VBITheCur33965_3846.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001738 Genomic DNA. Translation: ACY99286.1 .
    RefSeqi WP_012854070.1. NC_013510.1.
    YP_003301324.1. NC_013510.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACY99286 ; ACY99286 ; Tcur_3753 .
    GeneIDi 8605106.
    KEGGi tcu:Tcur_3753.
    PATRICi 32517274. VBITheCur33965_3846.

    Phylogenomic databases

    HOGENOMi HOG000247959.
    KOi K03657.
    OMAi TAVGDPC.
    OrthoDBi EOG6S7XR2.

    Enzyme and pathway databases

    BioCyci TCUR471852:GHHD-3816-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 5 hits.
    InterProi IPR014017. DNA_helicase_UvrD-like_C.
    IPR000212. DNA_helicase_UvrD/REP.
    IPR027417. P-loop_NTPase.
    IPR011335. Restrct_endonuc-II-like.
    IPR014016. UvrD-like_ATP-bd.
    [Graphical view ]
    PANTHERi PTHR11070. PTHR11070. 1 hit.
    Pfami PF00580. UvrD-helicase. 1 hit.
    PF13361. UvrD_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 3 hits.
    SSF52980. SSF52980. 1 hit.
    PROSITEi PS51198. UVRD_HELICASE_ATP_BIND. 1 hit.
    PS51217. UVRD_HELICASE_CTER. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081Imported.

    Entry informationi

    Entry nameiD1ACM7_THECD
    AccessioniPrimary (citable) accession number: D1ACM7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: January 19, 2010
    Last sequence update: January 19, 2010
    Last modified: October 1, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3