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D1ACM7

- D1ACM7_THECD

UniProt

D1ACM7 - D1ACM7_THECD

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Protein
Submitted name:

UvrD/REP helicase

Gene
Tcur_3753
Organism
Thermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein predictedi

Functioni

Catalytic activityi

ATP + H2O = ADP + phosphate.SAAS annotations

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. ATP-dependent DNA helicase activity Source: InterPro
  3. DNA binding Source: UniProtKB-KW
  4. exonuclease activity Source: UniProtKB-KW

GO - Biological processi

  1. DNA repair Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

ExonucleaseSAAS annotations, HelicaseSAAS annotationsImported, Hydrolase, Nuclease

Keywords - Biological processi

DNA damage, DNA repairSAAS annotations

Keywords - Ligandi

ATP-binding, DNA-bindingSAAS annotations, Nucleotide-binding

Enzyme and pathway databases

BioCyciTCUR471852:GHHD-3816-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
UvrD/REP helicaseImported
Gene namesi
Ordered Locus Names:Tcur_3753Imported
OrganismiThermomonospora curvata (strain ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081)Imported
Taxonomic identifieri471852 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptosporangineaeThermomonosporaceaeThermomonospora
ProteomesiUP000001918: Chromosome

Family & Domainsi

Sequence similaritiesi

Contains uvrD-like helicase ATP-binding domain.SAAS annotations
Contains uvrD-like helicase C-terminal domain.SAAS annotations

Phylogenomic databases

HOGENOMiHOG000247959.
KOiK03657.
OMAiTAVGDPC.
OrthoDBiEOG6S7XR2.

Family and domain databases

Gene3Di3.40.50.300. 5 hits.
InterProiIPR014017. DNA_helicase_UvrD-like_C.
IPR000212. DNA_helicase_UvrD/REP.
IPR027417. P-loop_NTPase.
IPR011335. Restrct_endonuc-II-like.
IPR014016. UvrD-like_ATP-bd.
[Graphical view]
PANTHERiPTHR11070. PTHR11070. 1 hit.
PfamiPF00580. UvrD-helicase. 1 hit.
PF13361. UvrD_C. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 3 hits.
SSF52980. SSF52980. 1 hit.
PROSITEiPS51198. UVRD_HELICASE_ATP_BIND. 1 hit.
PS51217. UVRD_HELICASE_CTER. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D1ACM7-1 [UniParc]FASTAAdd to Basket

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MITPVELARL LELPEPTPEQ ARVISAPLAP MAVIAGAGSG KSETMAARVV     50
WLVANGLVRP ERVLGLTFTR KAAGELATRI RRRLDQLRDR LPQDELDRLG 100
GEAALDGEPA VSTYHSYAAR LFGDHALRAA LEPTMRLISP AMAWQLAARV 150
VDDYDGAMDG IDWRPDTVVR AVLDLSGELA EHLRTPEDVR EIGRRLRAQF 200
DALPGRRGAA KNVLATQEIR ERLLPLVEAY QRAKIEREVL DYGDQVALAA 250
RIARDHPDVG MIERSRYAVV LLDEYQDTSH AQLVLLTSLF GGGHPVTAVG 300
DPCQSIYGWR GAGSGNLTGF PEDFPLAPAV PSRVAAVPPP RPGRRPPRHA 350
RPAPTATLSI SWRNGERILE VAARIQQGLR ADTANVPRLR PGEGRRGRGR 400
VECALLPTVT AEAEHIAERI RRLRAADPEL APDGLPWDEG PLKYSHIAVL 450
VRRRSQIPPL RKALEERDIP VEVVGLGGLL TVPEVQDVVA TLRVVHDPTA 500
GASLARLLTG PRWRIGPRDL VALGRRARRL ASENTRDITP PPDASELRPE 550
PAANAEETDP LRQVVIELTQ ETGSLVDALD DLGDPSAYSP EGLARLRRLA 600
AELRTLRSQV GLPLPDLVAE VERTLGLDIE VAARSGLDPA GARADLDAFI 650
ETAASFAEES ENPTLGAFLA YLKAAESEEF GLPAGRVSES DSVKLLTVHA 700
AKGLEWPVVV VPGLCYLPSG SGRPVKGSIF PSPPQQSTRW TDNPRLLPFE 750
LRGDYEKGNL PRLNGLTKAD LDRFKDECAD RDLREERRLA YVAVTRASHL 800
LIATGHRWGA TARPLHPSPF LEEIRQACET GAGRVVSWAD PPEEGAANPL 850
QAEAEPGRWP ATPEGRRYAA IVEGAEMVRD AMVGRIAPWA GDDGLTEADR 900
RRMTAWARDV ELLLAERDRG RGGDVLQVEL PAKLTVSTLV ALSRDPQEVA 950
RSIRRPMPRP PAPYARRGTA FHRWLESRWG QQRLLDPDEL PGAADEGAAD 1000
DSMLTELQRR FEESEWASRR PLDIEVTFET VLGDRVLRGR MDAVFTAPDG 1050
GYEVVDWKTG RPPADEDFRH AAVQLAAYRL AWADLAGVPL EKVSAAFHYV 1100
RYNRTIRPAD LLDRAGLTAL LENIRPID 1128
Length:1,128
Mass (Da):123,729
Last modified:January 19, 2010 - v1
Checksum:iB90C8BE20D7DCE7B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001738 Genomic DNA. Translation: ACY99286.1.
RefSeqiWP_012854070.1. NC_013510.1.
YP_003301324.1. NC_013510.1.

Genome annotation databases

EnsemblBacteriaiACY99286; ACY99286; Tcur_3753.
GeneIDi8605106.
KEGGitcu:Tcur_3753.
PATRICi32517274. VBITheCur33965_3846.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001738 Genomic DNA. Translation: ACY99286.1 .
RefSeqi WP_012854070.1. NC_013510.1.
YP_003301324.1. NC_013510.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACY99286 ; ACY99286 ; Tcur_3753 .
GeneIDi 8605106.
KEGGi tcu:Tcur_3753.
PATRICi 32517274. VBITheCur33965_3846.

Phylogenomic databases

HOGENOMi HOG000247959.
KOi K03657.
OMAi TAVGDPC.
OrthoDBi EOG6S7XR2.

Enzyme and pathway databases

BioCyci TCUR471852:GHHD-3816-MONOMER.

Family and domain databases

Gene3Di 3.40.50.300. 5 hits.
InterProi IPR014017. DNA_helicase_UvrD-like_C.
IPR000212. DNA_helicase_UvrD/REP.
IPR027417. P-loop_NTPase.
IPR011335. Restrct_endonuc-II-like.
IPR014016. UvrD-like_ATP-bd.
[Graphical view ]
PANTHERi PTHR11070. PTHR11070. 1 hit.
Pfami PF00580. UvrD-helicase. 1 hit.
PF13361. UvrD_C. 1 hit.
[Graphical view ]
SUPFAMi SSF52540. SSF52540. 3 hits.
SSF52980. SSF52980. 1 hit.
PROSITEi PS51198. UVRD_HELICASE_ATP_BIND. 1 hit.
PS51217. UVRD_HELICASE_CTER. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19995 / DSM 43183 / JCM 3096 / NCIMB 10081.

Entry informationi

Entry nameiD1ACM7_THECD
AccessioniPrimary (citable) accession number: D1ACM7
Entry historyi
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: September 3, 2014
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3

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