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Protein

Glutamate decarboxylase

Gene

gadB2

Organism
Edwardsiella tarda (strain EIB202)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciETAR498217:GJC4-2954-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Name:gadB2Imported
Ordered Locus Names:ETAE_2868Imported
OrganismiEdwardsiella tarda (strain EIB202)Imported
Taxonomic identifieri498217 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEdwardsiella
ProteomesiUP000002634 Componenti: Chromosome

Structurei

3D structure databases

ProteinModelPortaliD0ZDS2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0ZDS2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKGTDTRGG YLDSRFGSEA IRTAAEAHHF PQGEMREDIA FQVINDELFL
60 70 80 90 100
DGNARQNLAT FCQTWDDDYV HRLMDISINK NWIDKEEYPQ SAAIDLRCVN
110 120 130 140 150
MVADLWHAPR PADGQAVGTN TIGSSEACML GGMAMKWRWR AKRLAQGKSV
160 170 180 190 200
DKPNMVCGPV QVCWHKFARY WDVELREIPM APGKLFMDPE RMIAACDENT
210 220 230 240 250
IGVVPTFGVT YTGNYEMPDV LHKALDDLQA RTGLDIDMHV DAASGGFLAP
260 270 280 290 300
FCAPDIVWDF RLPRVKSISA SGHKFGLAPL GCGWVVWRDA ASLPDDLIFK
310 320 330 340 350
VDYLGGQVGT FAINFSRPAG QVIAQYYEFL RLGREGYTKV HTASYQVAQF
360 370 380 390 400
LAAEIAKLGP YEFICSGDPQ QGIPAVCFRI PAGKALGYSL YDLSERLRLR
410 420 430 440 450
GWQVPAFALN GEMSDVVVMR IMCRRGFEMD FAQLLMEDFR AALAYLKAHP
460
AVANVAHQNS FKHS
Length:464
Mass (Da):51,801
Last modified:January 19, 2010 - v1
Checksum:i4C91197AC5608011
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001135 Genomic DNA. Translation: ACY85701.1.
RefSeqiWP_012849691.1. NC_013508.1.
YP_003296912.1. NC_013508.1.

Genome annotation databases

EnsemblBacteriaiACY85701; ACY85701; ETAE_2868.
KEGGietr:ETAE_2868.
PATRICi32080804. VBIEdwTar116525_2650.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001135 Genomic DNA. Translation: ACY85701.1.
RefSeqiWP_012849691.1. NC_013508.1.
YP_003296912.1. NC_013508.1.

3D structure databases

ProteinModelPortaliD0ZDS2.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACY85701; ACY85701; ETAE_2868.
KEGGietr:ETAE_2868.
PATRICi32080804. VBIEdwTar116525_2650.

Phylogenomic databases

HOGENOMiHOG000070228.
KOiK01580.
OMAiDPDLVWD.
OrthoDBiEOG6TFCPW.

Enzyme and pathway databases

BioCyciETAR498217:GJC4-2954-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches."
    Wang Q., Yang M., Xiao J., Wu H., Wang X., Lv Y., Xu L., Zheng H., Wang S., Zhao G., Liu Q., Zhang Y.
    PLoS ONE 4:E7646-E7646(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: EIB202Imported.

Entry informationi

Entry nameiD0ZDS2_EDWTE
AccessioniPrimary (citable) accession number: D0ZDS2
Entry historyi
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: May 27, 2015
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.