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D0ZCJ9 (D0ZCJ9_EDWTE) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase RuleBase RU004136
EC=6.3.2.10 RuleBase RU004136
Gene names
Name:murF EMBL ACY83480.1
Ordered Locus Names:ETAE_0633 EMBL ACY83480.1
OrganismEdwardsiella tarda (strain EIB202) [Complete proteome] [HAMAP] EMBL ACY83480.1
Taxonomic identifier498217 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Edwardsiella ›

Protein attributes

Sequence length458 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein By similarity.

Catalytic activity

ATP + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysine + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-gamma-D-glutamyl-L-lysyl-D-alanyl-D-alanine.

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the MurCDEF family. RuleBase RU003630

Sequences

Sequence LengthMass (Da)Tools
D0ZCJ9 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: 45AED09554FDF673

FASTA45847,791
        10         20         30         40         50         60 
MIATTLQTLA DAIGATLIGA DSPVTAVTTD TRKLTPGCLF VALQGDNFDG HDFAAQAREG 

        70         80         90        100        110        120 
GAGALLVNRR LALDVPQLLV ADTRLALGQL GAWVRRQVPA RVVALTGSSG KTSVKEMSAA 

       130        140        150        160        170        180 
ILGLCGNVLY TAGNLNNDIG VPLTLLRLEP QHDFAVIELG ANHVGEIAYS VALTRPHSAL 

       190        200        210        220        230        240 
VNNLAAAHLE GFGSLSGVAQ AKGEIFAGLP PQGTAIVNAD SNDWENWQHA LTEQRVWRFS 

       250        260        270        280        290        300 
PQAGAGVDFY ASAVRSDAAG THFTLHTPAG QCDVLLPLPG RHNIANALAA AALTMSVGAT 

       310        320        330        340        350        360 
LTQVQQGLAG LQAVPGRLFP IRLGEHQLLL DDSYNANVGS MSAAAEVLGH MPGYRVMVVG 

       370        380        390        400        410        420 
DMAELGAEAE ACHRRVGQAA RAAGIDKVLS VGGLSRLIGE ASGCGEHFMD KTALIERLKH 

       430        440        450 
LLCEHAAITI LVKGSRSAAM EQVVRGVSVQ EMQENQSC

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References

[1]"Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches."
Wang Q., Yang M., Xiao J., Wu H., Wang X., Lv Y., Xu L., Zheng H., Wang S., Zhao G., Liu Q., Zhang Y.
PLoS ONE 4:E7646-E7646(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EIB202 EMBL ACY83480.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001135 Genomic DNA. Translation: ACY83480.1.
RefSeqYP_003294691.1. NC_013508.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACY83480; ACY83480; ETAE_0633.
GeneID8606985.
KEGGetr:ETAE_0633.
PATRIC32076562. VBIEdwTar116525_0592.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000268120.
KOK01929.
OMAGNRNNEI.

Enzyme and pathway databases

BioCycETAR498217:GJC4-664-MONOMER.
UniPathwayUPA00219.

Family and domain databases

Gene3D3.40.1190.10. 1 hit.
3.90.190.20. 1 hit.
InterProIPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
IPR000713. Mur_ligase_N.
IPR005863. UDP-N-AcMur-pentapeptide_synth.
[Graphical view]
PANTHERPTHR23135:SF3. PTHR23135:SF3. 1 hit.
PfamPF01225. Mur_ligase. 1 hit.
PF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
SUPFAMSSF53244. Mur_ligase_C. 1 hit.
SSF53623. Mur_ligase_cen. 1 hit.
TIGRFAMsTIGR01143. murF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD0ZCJ9_EDWTE
AccessionPrimary (citable) accession number: D0ZCJ9
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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