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D0ZB76 (D0ZB76_EDWTE) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 24. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
tRNA pseudouridine synthase B HAMAP-Rule MF_01080
EC=5.4.99.25 HAMAP-Rule MF_01080
Alternative name(s):
tRNA pseudouridine(55) synthase HAMAP-Rule MF_01080
tRNA pseudouridylate synthase HAMAP-Rule MF_01080
tRNA-uridine isomerase HAMAP-Rule MF_01080
Gene names
Name:truB HAMAP-Rule MF_01080 EMBL ACY83254.1
Ordered Locus Names:ETAE_0407 EMBL ACY83254.1
OrganismEdwardsiella tarda (strain EIB202) [Complete proteome] [HAMAP] EMBL ACY83254.1
Taxonomic identifier498217 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Edwardsiella ›

Protein attributes

Sequence length320 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs By similarity. HAMAP-Rule MF_01080 SAAS SAAS014780

Catalytic activity

tRNA uridine55 = tRNA pseudouridine55. HAMAP-Rule MF_01080 SAAS SAAS014780

Sequence similarities

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. HAMAP-Rule MF_01080

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site481Nucleophile By similarity HAMAP-Rule MF_01080
Binding site431Substrate By similarity HAMAP-Rule MF_01080
Binding site761Substrate By similarity HAMAP-Rule MF_01080
Binding site1791Substrate By similarity HAMAP-Rule MF_01080
Binding site2001Substrate By similarity HAMAP-Rule MF_01080

Sequences

Sequence LengthMass (Da)Tools
D0ZB76 [UniParc].

Last modified January 19, 2010. Version 1.
Checksum: 3B287CAACE80EB57

FASTA32035,623
        10         20         30         40         50         60 
MSRPRRRGRD INGVLLLDKG QGMSSNDVLQ KVKRIYNANK AGHTGALDPL ATGMLPICLG 

        70         80         90        100        110        120 
EATKFSQFLL DADKRYRVIA RLGQRTDTSD ADGQVVCERP LSFSEAELAQ ALEGFRGPGR 

       130        140        150        160        170        180 
QVPSMYSALK YQGRPLYEYA RQGIDVPRES REITVFELRF IRWEGDELEL EIHCSKGTYI 

       190        200        210        220        230        240 
RTIIDDLGEV LGCGAHVIYL RRLQVSGYPS ERMVTLEQLQ ALLAQAQQQE RDPRLLLDPL 

       250        260        270        280        290        300 
LLPMDTAAAH LPEVNLSEIV AGYVQLGQPV QTPDLPQSGM VRISVGAAHR FIGVGEVDDQ 

       310        320 
GRLAPRRMVV ESRLSEDDPT

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References

[1]"Genome sequence of the versatile fish pathogen Edwardsiella tarda provides insights into its adaptation to broad host ranges and intracellular niches."
Wang Q., Yang M., Xiao J., Wu H., Wang X., Lv Y., Xu L., Zheng H., Wang S., Zhao G., Liu Q., Zhang Y.
PLoS ONE 4:E7646-E7646(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: EIB202 EMBL ACY83254.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001135 Genomic DNA. Translation: ACY83254.1.
RefSeqYP_003294465.1. NC_013508.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACY83254; ACY83254; ETAE_0407.
GeneID8606759.
KEGGetr:ETAE_0407.
PATRIC32076114. VBIEdwTar116525_0376.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000231223.
KOK03177.
OMALGCGAYV.

Enzyme and pathway databases

BioCycETAR498217:GJC4-430-MONOMER.

Family and domain databases

HAMAPMF_01080. TruB_bact.
InterProIPR002501. PsdUridine_synth.
IPR020103. PsdUridine_synth_cat_dom.
IPR015947. PUA-like_domain.
IPR014780. tRNA_psdUridine_synth_TruB.
IPR015240. tRNA_sdUridine_synth_fam1_C.
[Graphical view]
PANTHERPTHR13767. PTHR13767. 1 hit.
PfamPF09157. TruB-C_2. 1 hit.
PF01509. TruB_N. 1 hit.
[Graphical view]
SUPFAMSSF55120. PsdUridine_synth_cat_dom. 1 hit.
SSF88697. PUA-like. 1 hit.
TIGRFAMsTIGR00431. TruB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD0ZB76_EDWTE
AccessionPrimary (citable) accession number: D0ZB76
Entry history
Integrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: May 1, 2013
This is version 24 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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