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Protein

Ribosomal RNA large subunit methyltransferase I

Gene

rlmI

Organism
Vibrio alginolyticus 40B
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the cytosine at position 1962 (m5C1962) of 23S rRNA.UniRule annotationSAAS annotation

Catalytic activityi

S-adenosyl-L-methionine + cytosine(1962) in 23S rRNA = S-adenosyl-L-homocysteine + 5-methylcytosine(1962) in 23S rRNA.UniRule annotationSAAS annotation

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferaseUniRule annotationSAAS annotation, RNA-bindingUniRule annotationSAAS annotation, Transferase
Biological processrRNA processingUniRule annotationSAAS annotation
LigandS-adenosyl-L-methionineUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA large subunit methyltransferase IUniRule annotationSAAS annotation (EC:2.1.1.191UniRule annotation)
Alternative name(s):
23S rRNA m5C1962 methyltransferaseUniRule annotation
rRNA (cytosine-C(5)-)-methyltransferase RlmIUniRule annotation
Gene namesi
Name:rlmIUniRule annotation
ORF Names:VMC_42050Imported
OrganismiVibrio alginolyticus 40BImported
Taxonomic identifieri674977 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
Proteomesi
  • UP000006248 Componenti: Unassembled WGS sequence

Subcellular locationi

D0X455:
  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi674977.VMC_42050.

Structurei

3D structure databases

ProteinModelPortaliD0X455.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini42 – 119PUAInterPro annotationAdd BLAST78

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RlmI family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105DR4. Bacteria.
COG1092. LUCA.

Family and domain databases

Gene3Di2.30.130.10. 1 hit.
HAMAPiMF_01857. 23SrRNA_methyltr_I. 1 hit.
InterProiView protein in InterPro
IPR002478. PUA.
IPR015947. PUA-like_domain.
IPR036974. PUA_sf.
IPR023542. rRNA_lsu_MeTfrase_I.
IPR019614. SAM-dep_methyl-trfase.
IPR029063. SAM-dependent_MTases.
PfamiView protein in Pfam
PF10672. Methyltrans_SAM. 1 hit.
SMARTiView protein in SMART
SM00359. PUA. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
SSF88697. SSF88697. 1 hit.
PROSITEiView protein in PROSITE
PS50890. PUA. 1 hit.

Sequencei

Sequence statusi: Complete.

D0X455-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTFLFEFKSH YNVLDCRGIL LLPSTSRTIR PFQNSTRANE MTAAIYLVKG
60 70 80 90 100
REKSVKRKHP WIFSRGINKV EGEPALGETV DVFTHDGKWL AKAAYSPASQ
110 120 130 140 150
IRARIWSFEK EEIDTAFFVK RLKDAQLLRE DIIERDGLTG YRLIAAESDG
160 170 180 190 200
LPGVTIDRYQ NFFVCQLLSA GAEHNKQAIV DALVECFPDC NVYERSDVAV
210 220 230 240 250
RKKEGLKEIT GVLHGEEPPQ SVVIEENGVK ISVDIVGGHK TGFYLDQRDS
260 270 280 290 300
RQQAMKYMKG KEVLNCFSYT GGFGLYALKG DAKRVINADV SQPALDTAKF
310 320 330 340 350
NAELNDFDIS KKRAVFLNAD VFKLLREYRD QGTQFDVVIM DPPKFAESKA
360 370 380 390 400
QLNGACRGYK DINMLAMQIL KPGGTLLTYS CSGLMDQVLF QKIIADAAVD
410 420 430
ANRQVKFVER FEQAADHPTD TAYPEGFYLK GFACKVL
Length:437
Mass (Da):49,098
Last modified:January 19, 2010 - v1
Checksum:i120036B4FC7D081A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
ACZB01000130 Genomic DNA. Translation: EEZ80943.1.

Genome annotation databases

EnsemblBacteriaiEEZ80943; EEZ80943; VMC_42050.

Similar proteinsi

Entry informationi

Entry nameiD0X455_VIBAL
AccessioniPrimary (citable) accession number: D0X455
Entry historyiIntegrated into UniProtKB/TrEMBL: January 19, 2010
Last sequence update: January 19, 2010
Last modified: October 25, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Keywords - Technical termi

Complete proteomeImported