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Protein
Submitted name:

Amino Transferase

Gene

RER070207001803

Organism
Eubacterium rectale
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

pyridoxal 5'-phosphateUniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei72 – 721N6-(pyridoxalphosphate)lysineCombined sources
Binding sitei134 – 1341N6-(pyridoxalphosphate)lysineCombined sources
Binding sitei183 – 1831N6-(pyridoxalphosphate)lysineCombined sources
Binding sitei256 – 2561N6-(pyridoxalphosphate)lysineCombined sources

GO - Molecular functioni

  1. pyridoxal phosphate binding Source: InterPro
  2. transaminase activity Source: UniProtKB-KW

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseUniRule annotation, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Amino TransferaseImported
Gene namesi
ORF Names:RER070207001803Imported
OrganismiEubacterium rectaleImported
Taxonomic identifieri39491 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaClostridialesEubacteriaceaeEubacterium

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3ELEX-ray2.10A/B/C/D1-398[»]
ProteinModelPortaliD0VX02.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiD0VX02.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni108 – 1092N6-(pyridoxalphosphate)lysine bindingCombined sources
Regioni217 – 2204N6-(pyridoxalphosphate)lysine bindingCombined sources
Regioni245 – 2484N6-(pyridoxalphosphate)lysine bindingCombined sources

Sequence similaritiesi

Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0VX02-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
GMVVNESMYQ LGSVRSAIRE LFEYGKKRAA IVGKENVYDF SIGNPSIPAP
60 70 80 90 100
QIVNDTIKEL VTDYDSVALH GYTSAQGDVE TRAAIAEFLN NTHGTHFNAD
110 120 130 140 150
NLYMTMGAAA SLSICFRALT SDAYDEFITI APYFPEYKVF VNAAGARLVE
160 170 180 190 200
VPADTEHFQI DFDALEERIN AHTRGVIINS PNNPSGTVYS EETIKKLSDL
210 220 230 240 250
LEKKSKEIGR PIFIIADEPY REIVYDGIKV PFVTKYYDNT LVCYSYSKSL
260 270 280 290 300
SLPGERIGYV LVPDEVYDKA ELYAAVCGAG RALGYVCAPS LFQKMIVKCQ
310 320 330 340 350
GATGDINAYK ENRDLLYEGL TRIGYHCFKP DGAFYMFVKA LEDDSNAFCE
360 370 380 390
KAKEEDVLIV AADGFGCPGW VRISYCVDRE MIKHSMPAFE KIYKKYNK
Length:398
Mass (Da):44,448
Last modified:December 15, 2009 - v1
Checksum:iBF4A60C9277B6FAD
GO

Cross-referencesi

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3ELEX-ray2.10A/B/C/D1-398[»]
ProteinModelPortaliD0VX02.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiD0VX02.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004839. Aminotransferase_I/II.
IPR004838. NHTrfase_class1_PyrdxlP-BS.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PfamiPF00155. Aminotran_1_2. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
PROSITEiPS00105. AA_TRANSFER_CLASS_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Crystal structure of Amino Transferase (RER070207001803) from Eubacterium rectale at 2.10 A resolution."
    Joint Center for Structural Genomics (JCSG)
    Submitted (SEP-2008) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH N6-(PYRIDOXALPHOSPHATE)LYSINE.

Entry informationi

Entry nameiD0VX02_9FIRM
AccessioniPrimary (citable) accession number: D0VX02
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: January 7, 2015
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.