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Protein

Phosphonoacetaldehyde hydrolase

Gene

phnX

Organism
Oleispira antarctica
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Involved in phosphonate degradation.UniRule annotationSAAS annotation

Catalytic activityi

Phosphonoacetaldehyde + H2O = acetaldehyde + phosphate.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei20NucleophileUniRule annotation1
Metal bindingi20MagnesiumUniRule annotation1
Metal bindingi22Magnesium; via carbonyl oxygenUniRule annotation1
Active sitei61Schiff-base intermediate with substrateUniRule annotation1
Metal bindingi194MagnesiumUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Schiff baseUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphonoacetaldehyde hydrolaseUniRule annotation (EC:3.11.1.1UniRule annotation)
Short name:
PhosphonataseUniRule annotation
Alternative name(s):
Phosphonoacetaldehyde phosphonohydrolaseUniRule annotation
Gene namesi
Name:phnXUniRule annotation
OrganismiOleispira antarcticaImported
Taxonomic identifieri188908 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaOceanospirillalesOleispira

Interactioni

Subunit structurei

Homodimer.UniRule annotationSAAS annotation

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3IRUX-ray2.30A/B1-277[»]
ProteinModelPortaliD0VWZ7.
SMRiD0VWZ7.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiD0VWZ7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 212HAD-like_domInterPro annotationAdd BLAST179

Sequence similaritiesi

Belongs to the HAD-like hydrolase superfamily. PhnX family.UniRule annotation

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01422. phosphonatase. 1 hit.

Sequencei

Sequence statusi: Complete.

D0VWZ7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GHMLKANVFC AGPVEALILD WAGTTIDFGS LAPVYAFMEL FKQEGIEVTQ
60 70 80 90 100
AEAREPMGTE KSEHIRRMLG NSRIANAWLS IKGQASNEED IKRLYDLFAP
110 120 130 140 150
IQTRIVAQRS QLIPGWKEVF DKLIAQGIKV GGNTGYGPGM MAPALIAAKE
160 170 180 190 200
QGYTPASTVF ATDVVRGRPF PDMALKVALE LEVGHVNGCI KVDDTLPGIE
210 220 230 240 250
EGLRAGMWTV GVSCSGNEVG LDREDWQALS SDEQQSYRQH AEQRLFNAGA
260 270
HYVIDSVADL ETVITDVNRR LARGEKP
Length:277
Mass (Da):30,302
Last modified:December 15, 2009 - v1
Checksum:iA1FA7397005FC55F
GO

Cross-referencesi

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3IRUX-ray2.30A/B1-277[»]
ProteinModelPortaliD0VWZ7.
SMRiD0VWZ7.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Miscellaneous databases

EvolutionaryTraceiD0VWZ7.

Family and domain databases

Gene3Di1.10.150.240. 1 hit.
3.40.50.1000. 2 hits.
HAMAPiMF_01375. PhnX. 1 hit.
InterProiIPR023214. HAD-like_dom.
IPR006439. HAD-SF_hydro_IA.
IPR023198. PGP_dom2.
IPR006323. Phosphonoacetald_hydro.
[Graphical view]
PfamiPF13419. HAD_2. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 1 hit.
TIGRFAMsiTIGR01509. HAD-SF-IA-v3. 1 hit.
TIGR01422. phosphonatase. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiD0VWZ7_OLEAN
AccessioniPrimary (citable) accession number: D0VWZ7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: November 30, 2016
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sourcesImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.