ID   RL36A_CANLF             Reviewed;         106 AA.
AC   D0VWQ4;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   15-DEC-2009, sequence version 1.
DT   27-MAR-2024, entry version 92.
DE   RecName: Full=Large ribosomal subunit protein eL42 {ECO:0000305};
DE   AltName: Full=60S ribosomal protein L36a;
DE   AltName: Full=60S ribosomal protein L44;
GN   Name=Rpl36a; Synonyms=Rpl44;
OS   Canis lupus familiaris (Dog) (Canis familiaris).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis.
OX   NCBI_TaxID=9615;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Boxer;
RX   PubMed=16341006; DOI=10.1038/nature04338;
RA   Lindblad-Toh K., Wade C.M., Mikkelsen T.S., Karlsson E.K., Jaffe D.B.,
RA   Kamal M., Clamp M., Chang J.L., Kulbokas E.J. III, Zody M.C., Mauceli E.,
RA   Xie X., Breen M., Wayne R.K., Ostrander E.A., Ponting C.P., Galibert F.,
RA   Smith D.R., deJong P.J., Kirkness E.F., Alvarez P., Biagi T., Brockman W.,
RA   Butler J., Chin C.-W., Cook A., Cuff J., Daly M.J., DeCaprio D., Gnerre S.,
RA   Grabherr M., Kellis M., Kleber M., Bardeleben C., Goodstadt L., Heger A.,
RA   Hitte C., Kim L., Koepfli K.-P., Parker H.G., Pollinger J.P.,
RA   Searle S.M.J., Sutter N.B., Thomas R., Webber C., Baldwin J., Abebe A.,
RA   Abouelleil A., Aftuck L., Ait-Zahra M., Aldredge T., Allen N., An P.,
RA   Anderson S., Antoine C., Arachchi H., Aslam A., Ayotte L., Bachantsang P.,
RA   Barry A., Bayul T., Benamara M., Berlin A., Bessette D., Blitshteyn B.,
RA   Bloom T., Blye J., Boguslavskiy L., Bonnet C., Boukhgalter B., Brown A.,
RA   Cahill P., Calixte N., Camarata J., Cheshatsang Y., Chu J., Citroen M.,
RA   Collymore A., Cooke P., Dawoe T., Daza R., Decktor K., DeGray S.,
RA   Dhargay N., Dooley K., Dooley K., Dorje P., Dorjee K., Dorris L.,
RA   Duffey N., Dupes A., Egbiremolen O., Elong R., Falk J., Farina A., Faro S.,
RA   Ferguson D., Ferreira P., Fisher S., FitzGerald M., Foley K., Foley C.,
RA   Franke A., Friedrich D., Gage D., Garber M., Gearin G., Giannoukos G.,
RA   Goode T., Goyette A., Graham J., Grandbois E., Gyaltsen K., Hafez N.,
RA   Hagopian D., Hagos B., Hall J., Healy C., Hegarty R., Honan T., Horn A.,
RA   Houde N., Hughes L., Hunnicutt L., Husby M., Jester B., Jones C., Kamat A.,
RA   Kanga B., Kells C., Khazanovich D., Kieu A.C., Kisner P., Kumar M.,
RA   Lance K., Landers T., Lara M., Lee W., Leger J.-P., Lennon N., Leuper L.,
RA   LeVine S., Liu J., Liu X., Lokyitsang Y., Lokyitsang T., Lui A.,
RA   Macdonald J., Major J., Marabella R., Maru K., Matthews C., McDonough S.,
RA   Mehta T., Meldrim J., Melnikov A., Meneus L., Mihalev A., Mihova T.,
RA   Miller K., Mittelman R., Mlenga V., Mulrain L., Munson G., Navidi A.,
RA   Naylor J., Nguyen T., Nguyen N., Nguyen C., Nguyen T., Nicol R., Norbu N.,
RA   Norbu C., Novod N., Nyima T., Olandt P., O'Neill B., O'Neill K., Osman S.,
RA   Oyono L., Patti C., Perrin D., Phunkhang P., Pierre F., Priest M.,
RA   Rachupka A., Raghuraman S., Rameau R., Ray V., Raymond C., Rege F.,
RA   Rise C., Rogers J., Rogov P., Sahalie J., Settipalli S., Sharpe T.,
RA   Shea T., Sheehan M., Sherpa N., Shi J., Shih D., Sloan J., Smith C.,
RA   Sparrow T., Stalker J., Stange-Thomann N., Stavropoulos S., Stone C.,
RA   Stone S., Sykes S., Tchuinga P., Tenzing P., Tesfaye S., Thoulutsang D.,
RA   Thoulutsang Y., Topham K., Topping I., Tsamla T., Vassiliev H.,
RA   Venkataraman V., Vo A., Wangchuk T., Wangdi T., Weiand M., Wilkinson J.,
RA   Wilson A., Yadav S., Yang S., Yang X., Young G., Yu Q., Zainoun J.,
RA   Zembek L., Zimmer A., Lander E.S.;
RT   "Genome sequence, comparative analysis and haplotype structure of the
RT   domestic dog.";
RL   Nature 438:803-819(2005).
RN   [2]
RP   STRUCTURE BY ELECTRON MICROSCOPY (8.70 ANGSTROMS).
RX   PubMed=18400176; DOI=10.1016/j.str.2008.01.007;
RA   Chandramouli P., Topf M., Menetret J.F., Eswar N., Cannone J.J.,
RA   Gutell R.R., Sali A., Akey C.W.;
RT   "Structure of the mammalian 80S ribosome at 8.7 A resolution.";
RL   Structure 16:535-548(2008).
CC   -!- FUNCTION: Component of the large ribosomal subunit. The ribosome is a
CC       large ribonucleoprotein complex responsible for the synthesis of
CC       proteins in the cell. {ECO:0000250|UniProtKB:P83881}.
CC   -!- SUBUNIT: Component of the large ribosomal subunit.
CC       {ECO:0000250|UniProtKB:P83881}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P83881}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL42 family.
CC       {ECO:0000305}.
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DR   RefSeq; NP_001300729.1; NM_001313800.1.
DR   PDB; 4V5Z; EM; 8.70 A; 4=1-106.
DR   PDBsum; 4V5Z; -.
DR   AlphaFoldDB; D0VWQ4; -.
DR   SMR; D0VWQ4; -.
DR   STRING; 9615.ENSCAFP00000026100; -.
DR   PaxDb; 9612-ENSCAFP00000034850; -.
DR   Ensembl; ENSCAFT00030001028.1; ENSCAFP00030000891.1; ENSCAFG00030000628.1.
DR   GeneID; 480311; -.
DR   KEGG; cfa:480311; -.
DR   CTD; 6166; -.
DR   eggNOG; KOG3464; Eukaryota.
DR   HOGENOM; CLU_114645_2_1_1; -.
DR   InParanoid; D0VWQ4; -.
DR   OMA; CKCHKVH; -.
DR   OrthoDB; 145007at2759; -.
DR   TreeFam; TF300213; -.
DR   Reactome; R-CFA-156827; L13a-mediated translational silencing of Ceruloplasmin expression.
DR   Reactome; R-CFA-1799339; SRP-dependent cotranslational protein targeting to membrane.
DR   Reactome; R-CFA-6791226; Major pathway of rRNA processing in the nucleolus and cytosol.
DR   Reactome; R-CFA-72689; Formation of a pool of free 40S subunits.
DR   Reactome; R-CFA-72706; GTP hydrolysis and joining of the 60S ribosomal subunit.
DR   Reactome; R-CFA-975956; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
DR   Reactome; R-CFA-975957; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
DR   EvolutionaryTrace; D0VWQ4; -.
DR   Proteomes; UP000002254; Unplaced.
DR   Proteomes; UP000694429; Chromosome 8.
DR   Proteomes; UP000694542; Unplaced.
DR   Proteomes; UP000805418; Unplaced.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR   GO; GO:0006412; P:translation; IEA:InterPro.
DR   Gene3D; 3.10.450.80; -; 1.
DR   InterPro; IPR000552; Ribosomal_eL44.
DR   InterPro; IPR011332; Ribosomal_zn-bd.
DR   PANTHER; PTHR10369:SF3; 60S RIBOSOMAL PROTEIN L36A; 1.
DR   PANTHER; PTHR10369; 60S RIBOSOMAL PROTEIN L36A/L44; 1.
DR   Pfam; PF00935; Ribosomal_L44; 1.
DR   SUPFAM; SSF57829; Zn-binding ribosomal proteins; 1.
DR   PROSITE; PS01172; RIBOSOMAL_L44E; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Reference proteome; Ribonucleoprotein;
KW   Ribosomal protein.
FT   CHAIN           1..106
FT                   /note="Large ribosomal subunit protein eL42"
FT                   /id="PRO_0000405592"
FT   REGION          34..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   106 AA;  12441 MW;  AE3308265D70BD26 CRC64;
     MVNVPKTRRT FCKKCGKHQP HKVTQYKKGK DSLYAQGKRR YDRKQSGYGG QTKPIFRKKA
     KTTKKIVLRL ECVEPNCRSK RMLAIKRCKH FELGGDKKRK GQVIQF
//