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D0VKF5 (BGLA_ASPTE) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 18. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable beta-glucosidase A

EC=3.2.1.21
Alternative name(s):
Beta-D-glucoside glucohydrolase A
Cellobiase A
Gentiobiase A
Gene names
Name:bglA
Synonyms:bgl1
OrganismAspergillus terreus
Taxonomic identifier33178 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length861 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Beta-glucosidases are one of a number of cellulolytic enzymes involved in the degradation of cellulosic biomass. Catalyzes the last step releasing glucose from the inhibitory cellobiose By similarity.

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.

Pathway

Glycan metabolism; cellulose degradation.

Subcellular location

Secreted By similarity.

Sequence similarities

Belongs to the glycosyl hydrolase 3 family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Cellular componentSecreted
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentextracellular region

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionbeta-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Potential
Chain20 – 861842Probable beta-glucosidase A
PRO_0000394098

Sites

Active site2811 By similarity

Amino acid modifications

Glycosylation621N-linked (GlcNAc...) Potential
Glycosylation2121N-linked (GlcNAc...) Potential
Glycosylation2531N-linked (GlcNAc...) Potential
Glycosylation3161N-linked (GlcNAc...) Potential
Glycosylation3231N-linked (GlcNAc...) Potential
Glycosylation3551N-linked (GlcNAc...) Potential
Glycosylation5241N-linked (GlcNAc...) Potential
Glycosylation5431N-linked (GlcNAc...) Potential
Glycosylation5651N-linked (GlcNAc...) Potential
Glycosylation6691N-linked (GlcNAc...) Potential
Glycosylation7131N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
D0VKF5 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: F0D2FDF24D07B8D0

FASTA86193,333
        10         20         30         40         50         60 
MKLSILEAAA LTAASVASAQ DDLAYSPPYY PSPWADGHGE WSNAYKRAVD IVSQMTLTEK 

        70         80         90        100        110        120 
VNLTTGTGWE LERCVGQTGS VPRLGIPSLC LQDSPLGIRM SDYNSAFPAG INVAATWDKT 

       130        140        150        160        170        180 
LAYQRGKAMG EEFSDKGIDV QLGPAAGPLG RSPDGGRNWE GFSPDPALTG VLFAETIKGI 

       190        200        210        220        230        240 
QDAGVIATAK HYILNEQEHF RQVGEAQGYG FNITETVSSN VDDKTMHELY LWPFADAVRA 

       250        260        270        280        290        300 
GVGAVMCSYN QINNSYGCQN SLTLNKLLKA ELGFQGFVMS DWSAHHSGVG AALAGLDMSM 

       310        320        330        340        350        360 
PGDISFDSGT SFYGTNLTVG VLNGTIPQWR VDDMAVRIMA AYYKVGRDRL WTPPNFSSWT 

       370        380        390        400        410        420 
RDEYGFAHFF PSEGAYERVN EFVNVQRDHA QVIRRIGADS VVLLKNDGAL PLTGQEKTVG 

       430        440        450        460        470        480 
ILGEDAGSNP KGANGCSDRG CDKGTLAMAW GSGTANFPYL VTPEQAIQNE VLKGRGNVFA 

       490        500        510        520        530        540 
VTDNYDTQQI AAVASQSTVS LVFVNADAGE GYLNVDGNMG DRKNLTLWQN GEEVIKTVTE 

       550        560        570        580        590        600 
HCNNTVVVIH SVGPVLIDEW YAHPNVTGIL WAGLPGQESG NAIADVLYGR VNPGGKTPFT 

       610        620        630        640        650        660 
WGKTRASYGD YLLTEPNNGN GAPQDNFNEG VFIDYRRFDK YNETPIYEFG HGLSYTTFEL 

       670        680        690        700        710        720 
SGLQVQLING SSYVPTTGQT SAAQTFGKVE DASSYLYPEG LKRISKFIYP WLNSTDLKAS 

       730        740        750        760        770        780 
TGDPDYGEPN FEYIPEGATD GSPQPRLPAS GGPGGNPGLY EDLFQVSVTI TNTGKVAGDE 

       790        800        810        820        830        840 
VPQLYVSLGG PNEPKRVLRK FERLHLAPGQ QKVWTTTLNR RDLANWDVVA QDWKITPYAK 

       850        860 
TIFVGTSSRK LPLAGRLPRV Q 

« Hide

References

[1]Abdul Hani A.M., Shaiful Adzni S., Nik Marzuki S.
Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: SUK-1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
GU078571 mRNA. Translation: ACY03273.1.

3D structure databases

ProteinModelPortalD0VKF5.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG1472.

Enzyme and pathway databases

UniPathwayUPA00696.

Family and domain databases

Gene3D3.20.20.300. 1 hit.
3.40.50.1700. 1 hit.
InterProIPR026891. Fn3-like.
IPR026892. Glyco_hydro_3.
IPR019800. Glyco_hydro_3_AS.
IPR002772. Glyco_hydro_3_C.
IPR001764. Glyco_hydro_3_N.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERPTHR30620. PTHR30620. 1 hit.
PfamPF14310. Fn3-like. 1 hit.
PF00933. Glyco_hydro_3. 1 hit.
PF01915. Glyco_hydro_3_C. 1 hit.
[Graphical view]
PRINTSPR00133. GLHYDRLASE3.
SUPFAMSSF51445. SSF51445. 1 hit.
SSF52279. SSF52279. 2 hits.
PROSITEPS00775. GLYCOSYL_HYDROL_F3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameBGLA_ASPTE
AccessionPrimary (citable) accession number: D0VKF5
Entry history
Integrated into UniProtKB/Swiss-Prot: May 18, 2010
Last sequence update: December 15, 2009
Last modified: November 13, 2013
This is version 18 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries