D0RB87 (D0RB87_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
MHC class II antigen EMBL CBH31054.1

Gene names

Name:

HLA-DRB1 EMBL CBH31054.1

Organism

Homo sapiens (Human) EMBL CBH31054.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	183 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 Ig-like C1-type (immunoglobulin-like) domain. SAAS SAAS003597

Ontologies

Keywords
Biological process	Immunity
Cellular component	MHC II SAAS SAAS003597 RuleBase RU000321 Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS014745
Gene Ontology (GO)
Biological_process	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Inferred from electronic annotation. Source: UniProtKB-KW immune response Inferred from electronic annotation. Source: InterPro
Cellular_component	MHC class II protein complex Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	1	1	EMBL CBH31054.1
	Non-terminal residue	183	1	EMBL CBH31054.1

Sequences

	Sequence		Length	Mass (Da)
	D0RB87 [UniParc]. Last modified December 15, 2009. Version 1. Checksum: 3CF9607B4FCCA681	FASTA	183	21,425
	10 20 30 40 50 60 RFLEYSTSEC HFFNGTERVR YLDRYFHNQE ENVRFDSDVG EFRAVTELGR PDAEYWNSQK 70 80 90 100 110 120 DLLEQKRGRV DNYCRHNYGV VESFTVQRRV HPKVTVYPSK TQPLQHHNLL VCSVSGFYPG 130 140 150 160 170 180 SIEVRWFRNG QEEKTGVVST GLIHNGDWTF QTLVMLETVP RSGEVYTCQV EHPSVTSPLT VEW

References

[1]	"New sequences found during HLA sequence typing." Anholts J.D.H. Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Blood EMBL CBH31054.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	FN563146 Genomic DNA. Translation: CBH31054.1.
IPI	IPI00956491.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	D0RB87.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Gene expression databases
ArrayExpress	D0RB87.
Family and domain databases
Gene3D	2.60.40.10. 1 hit. 3.10.320.10. 1 hit.
InterPro	IPR007110. Ig-like_dom. IPR013783. Ig-like_fold. IPR003006. Ig/MHC_CS. IPR003597. Ig_C1-set. IPR011162. MHC_I/II-like_Ag-recog. IPR014745. MHC_II_a/b_N. IPR000353. MHC_II_b_N. [Graphical view]
Pfam	PF07654. C1-set. 1 hit. PF00969. MHC_II_beta. 1 hit. [Graphical view]
ProDom	PD000328. MHC_II_b_N. 1 hit. [Graphical view] [Entries sharing at least one domain]
SMART	SM00407. IGc1. 1 hit. SM00921. MHC_II_beta. 1 hit. [Graphical view]
SUPFAM	SSF54452. MHC_I/II-like_Ag-recog. 1 hit.
PROSITE	PS50835. IG_LIKE. 1 hit. PS00290. IG_MHC. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	HLA-DRB1. human.
NextBio	35488952.

Entry information

Entry name

D0RB87_HUMAN

Accession

Primary (citable) accession number: D0RB87

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2009
Last sequence update:	December 15, 2009
Last modified:	April 3, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.