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D0RB87

- D0RB87_HUMAN

UniProt

D0RB87 - D0RB87_HUMAN

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Protein
Submitted name:

MHC class II antigen

Gene

HLA-DRB1

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. antigen processing and presentation of peptide or polysaccharide antigen via MHC class II Source: UniProtKB-KW
  2. immune response Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Immunity

Names & Taxonomyi

Protein namesi
Submitted name:
MHC class II antigenImported
Gene namesi
Name:HLA-DRB1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. MHC class II protein complex Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, MHC IIUniRule annotationSAAS annotation

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains Ig-like C1-type (immunoglobulin-like) domain.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProiIPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view]
PfamiPF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
[Graphical view]
ProDomiPD000328. MHC_II_b_N. 1 hit.
[Graphical view] [Entries sharing at least one domain]
SMARTiSM00407. IGc1. 1 hit.
SM00921. MHC_II_beta. 1 hit.
[Graphical view]
SUPFAMiSSF54452. SSF54452. 1 hit.
PROSITEiPS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

D0RB87-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
RFLEYSTSEC HFFNGTERVR YLDRYFHNQE ENVRFDSDVG EFRAVTELGR
60 70 80 90 100
PDAEYWNSQK DLLEQKRGRV DNYCRHNYGV VESFTVQRRV HPKVTVYPSK
110 120 130 140 150
TQPLQHHNLL VCSVSGFYPG SIEVRWFRNG QEEKTGVVST GLIHNGDWTF
160 170 180
QTLVMLETVP RSGEVYTCQV EHPSVTSPLT VEW
Length:183
Mass (Da):21,425
Last modified:December 15, 2009 - v1
Checksum:i3CF9607B4FCCA681
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported
Non-terminal residuei183 – 1831Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN563146 Genomic DNA. Translation: CBH31054.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FN563146 Genomic DNA. Translation: CBH31054.1 .

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Miscellaneous databases

ChiTaRSi HLA-DRB1. human.
NextBioi 35488952.

Family and domain databases

Gene3Di 2.60.40.10. 1 hit.
3.10.320.10. 1 hit.
InterProi IPR007110. Ig-like_dom.
IPR013783. Ig-like_fold.
IPR003006. Ig/MHC_CS.
IPR003597. Ig_C1-set.
IPR011162. MHC_I/II-like_Ag-recog.
IPR014745. MHC_II_a/b_N.
IPR000353. MHC_II_b_N.
[Graphical view ]
Pfami PF07654. C1-set. 1 hit.
PF00969. MHC_II_beta. 1 hit.
[Graphical view ]
ProDomi PD000328. MHC_II_b_N. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
SMARTi SM00407. IGc1. 1 hit.
SM00921. MHC_II_beta. 1 hit.
[Graphical view ]
SUPFAMi SSF54452. SSF54452. 1 hit.
PROSITEi PS50835. IG_LIKE. 1 hit.
PS00290. IG_MHC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "New sequences found during HLA sequence typing."
    Anholts J.D.H.
    Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BloodImported.

Entry informationi

Entry nameiD0RB87_HUMAN
AccessioniPrimary (citable) accession number: D0RB87
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: October 29, 2014
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.