Skip Header

Contribute Send feedback
Read comments (?) or add your own

D0R4F1 (D0R4F1_LACJF) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 25. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Ribonuclease HII HAMAP-Rule MF_00052
Short name=RNase HII HAMAP-Rule MF_00052
EC=3.1.26.4 HAMAP-Rule MF_00052
Gene names
Name:rnhB HAMAP-Rule MF_00052 EMBL CAX66964.1
Ordered Locus Names:FI9785_1100 EMBL CAX66964.1
OrganismLactobacillus johnsonii (strain FI9785) [Complete proteome] [HAMAP] EMBL CAX66964.1
Taxonomic identifier633699 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus ›

Protein attributes

Sequence length250 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids By similarity. RuleBase RU003515 SAAS SAAS022898 HAMAP-Rule MF_00052

Catalytic activity

Endonucleolytic cleavage to 5'-phosphomonoester. RuleBase RU003515 SAAS SAAS022898 HAMAP-Rule MF_00052

Cofactor

Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding By similarity. SAAS SAAS022898 HAMAP-Rule MF_00052

Subcellular location

Cytoplasm By similarity SAAS SAAS022898 HAMAP-Rule MF_00052.

Sequence similarities

Belongs to the RNase HII family. RuleBase RU003515 HAMAP-Rule MF_00052

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding721Divalent metal cation By similarity HAMAP-Rule MF_00052
Metal binding731Divalent metal cation By similarity HAMAP-Rule MF_00052
Metal binding1641Divalent metal cation By similarity HAMAP-Rule MF_00052

Sequences

Sequence LengthMass (Da)Tools
D0R4F1 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: 9D8A0E00E8901CE9

FASTA25027,948
        10         20         30         40         50         60 
MTITEIKNLL QGEVSKEQLE ELKADERKGV QKLLISYEKR QAKYAKALAQ FQSRFSYEKE 

        70         80         90        100        110        120 
FWQKDQLVAG VDEVGRGPLA GPVVTAAVIL PHDFDLIDVN DSKKLSPKKR QALFPKILEK 

       130        140        150        160        170        180 
AVSVSVGLAN NDLIDQINIY EADRVAMAHA VQGLKVKPDA LLVDAMNVPL NIPQVKLIHG 

       190        200        210        220        230        240 
DAKSNSIAAA SIVAKVFRDN LMDAYGELYP EYDFKHNAGY GTREHMEALK KYGPTPIHRR 

       250 
SFAPVSEYEK

« Hide

References

[1]"Complete genome sequence of Lactobacillus johnsonii FI9785, a competitive exclusion agent against pathogens in poultry."
Wegmann U., Overweg K., Horn N., Goesmann A., Narbad A., Gasson M.J., Shearman C.
J. Bacteriol. 191:7142-7143(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: FI9785 EMBL CAX66964.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FN298497 Genomic DNA. Translation: CAX66964.1.
RefSeqYP_003293231.1. NC_013504.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING633699.FI9785_1100.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAX66964; CAX66964; FI9785_1100.
GeneID8570867.
KEGGljf:FI9785_1100.
PATRIC32246789. VBILacJoh137736_1025.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0164.
HOGENOMHOG000100288.
KOK03470.

Enzyme and pathway databases

BioCycLJOH633699:GJ95-1033-MONOMER.

Family and domain databases

HAMAPMF_00052_B. RNase_HII_B.
InterProIPR022898. RNase_HII.
IPR001352. RNase_HII/HIII.
IPR024567. RNase_HII/HIII_dom.
IPR012337. RNaseH-like_dom.
[Graphical view]
PANTHERPTHR10954. PTHR10954. 1 hit.
PfamPF01351. RNase_HII. 1 hit.
[Graphical view]
SUPFAMSSF53098. RNaseH_fold. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD0R4F1_LACJF
AccessionPrimary (citable) accession number: D0R4F1
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: May 1, 2013
This is version 25 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info