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Protein
Submitted name:

Lysyl oxidase

Gene

LOX

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Lysyl oxidaseImported
Gene namesi
Name:LOXImported
ORF Names:hCG_37363Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000113083.12.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30427.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501108903122 – 417Sequence analysisAdd BLAST396

Expressioni

Gene expression databases

BgeeiENSG00000113083.

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IHTH. Eukaryota.
ENOG41101E4. LUCA.
KOiK00277.
OMAiYSDDNPY.
OrthoDBiEOG091G02XD.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
InterProiView protein in InterPro
IPR013783. Ig-like_fold.
IPR001695. Lysyl_oxidase.
IPR019828. Lysyl_oxidase_CS.
PfamiView protein in Pfam
PF01186. Lysyl_oxidase. 1 hit.
PRINTSiPR00074. LYSYLOXIDASE.
PROSITEiView protein in PROSITE
PS00926. LYSYL_OXIDASE. 1 hit.

Sequencei

Sequence statusi: Complete.

D0PNI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFAWTVLLL GPLQLCALVH CAPPAAGQQQ PPREPPAAPG AWRQQIQWEN
60 70 80 90 100
NGQVFSLLSL GSQYQPQRRR DPGAAVPGAA NASAQQPRTP ILLIRDNRTA
110 120 130 140 150
AARTRTAGSS GVTAGRPRPT ARHWFQAGYS TSRAREAGAS RAENQTAPGE
160 170 180 190 200
VPALSNLRPP SRVDGMVGDD PYNPYKYSDD NPYYNYYDTY ERPRPGGRYR
210 220 230 240 250
PGYGTGYFQY GLPDLVADPY YIQASTYVQK MSMYNLRCAA EENCLASTAY
260 270 280 290 300
RADVRDYDHR VLLRFPQRVK NQGTSDFLPS RPRYSWEWHS CHQHYHSMDE
310 320 330 340 350
FSHYDLLDAN TQRRVAEGHK ASFCLEDTSC DYGYHRRFAC TAHTQGLSPG
360 370 380 390 400
CYDTYGADID CQWIDITDVK PGNYILKVSV NPSYLVPESD YTNNVVRCDI
410
RYTGHHAYAS GCTISPY
Length:417
Mass (Da):46,944
Last modified:December 15, 2009 - v1
Checksum:i6412A78443E03F04
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF094938 Genomic DNA. Translation: ABO15004.1.
CH471086 Genomic DNA. Translation: EAW48898.1.
RefSeqiNP_002308.2. NM_002317.6.
UniGeneiHs.102267.

Genome annotation databases

GeneIDi4015.
KEGGihsa:4015.

Similar proteinsi

Entry informationi

Entry nameiD0PNI2_HUMAN
AccessioniPrimary (citable) accession number: D0PNI2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: October 25, 2017
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.