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Protein
Submitted name:

Epididymis luminal protein 4

Gene

YWHAZ

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMonooxygenaseImported, Oxidoreductase

Names & Taxonomyi

Protein namesi
Submitted name:
Epididymis luminal protein 4Imported
Submitted name:
Epididymis secretory protein Li 3Imported
Submitted name:
Epididymis secretory protein Li 93Imported
Submitted name:
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta polypeptideImported
Submitted name:
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide, isoform CRA_aImported
Gene namesi
Name:YWHAZImported
Synonyms:HEL-S-3Imported, HEL-S-93Imported, HEL4Imported
ORF Names:hCG_2009146Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA37444.

Expressioni

Gene expression databases

BgeeiENSG00000164924.
ExpressionAtlasiD0PNI1. baseline and differential.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

IntActiD0PNI1. 1 interactor.

Structurei

3D structure databases

SMRiD0PNI1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 24214_3_3InterPro annotationAdd BLAST240

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili65 – 92Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the 14-3-3 family.UniRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0841. Eukaryota.
COG5040. LUCA.
KOiK16197.

Family and domain databases

Gene3Di1.20.190.20. 1 hit.
InterProiView protein in InterPro
IPR000308. 14-3-3.
IPR023409. 14-3-3_CS.
IPR023410. 14-3-3_domain.
PANTHERiPTHR18860. PTHR18860. 1 hit.
PfamiView protein in Pfam
PF00244. 14-3-3. 1 hit.
PIRSFiPIRSF000868. 14-3-3. 1 hit.
PRINTSiPR00305. 1433ZETA.
SMARTiView protein in SMART
SM00101. 14_3_3. 1 hit.
SUPFAMiSSF48445. SSF48445. 1 hit.
PROSITEiView protein in PROSITE
PS00796. 1433_1. 1 hit.
PS00797. 1433_2. 1 hit.

Sequencei

Sequence statusi: Complete.

D0PNI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDKNELVQKA KLAEQAERYD DMAACMKSVT EQGAELSNEE RNLLSVAYKN
60 70 80 90 100
VVGARRSSWR VVSSIEQKTE GAEKKQQMAR EYREKIETEL RDICNDVLSL
110 120 130 140 150
LEKFLIPNAS QAESKVFYLK MKGDYYRYLA EVAAGDDKKG IVDQSQQAYQ
160 170 180 190 200
EAFEISKKEM QPTHPIRLGL ALNFSVFYYE ILNSPEKACS LAKTAFDEAI
210 220 230 240
AELDTLSEES YKDSTLIMQL LRDNLTLWTS DTQGDEAEAG EGGEN
Length:245
Mass (Da):27,745
Last modified:December 15, 2009 - v1
Checksum:iD464DF2286BBFE60
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EF094937 Genomic DNA. Translation: ABO15003.1.
EU794582 mRNA. Translation: ACJ13636.1.
EU794583 mRNA. Translation: ACJ13637.1.
GQ472215 mRNA. Translation: ACV87190.1.
CH471060 Genomic DNA. Translation: EAW91824.1.
CH471060 Genomic DNA. Translation: EAW91825.1.
CH471060 Genomic DNA. Translation: EAW91826.1.
CH471060 Genomic DNA. Translation: EAW91827.1.
CH471060 Genomic DNA. Translation: EAW91828.1.
CH471060 Genomic DNA. Translation: EAW91829.1.
RefSeqiNP_001129171.1. NM_001135699.1.
NP_001129172.1. NM_001135700.1.
NP_001129173.1. NM_001135701.1.
NP_001129174.1. NM_001135702.1.
NP_003397.1. NM_003406.3.
NP_663723.1. NM_145690.2.
XP_005251118.1. XM_005251061.3.
XP_005251120.1. XM_005251063.3.
XP_016869299.1. XM_017013810.1.
XP_016869300.1. XM_017013811.1.
UniGeneiHs.492407.

Genome annotation databases

GeneIDi7534.
KEGGihsa:7534.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiD0PNI1_HUMAN
AccessioniPrimary (citable) accession number: D0PNI1
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: July 5, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.