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D0PBB7 (D0PBB7_BRUSS) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Pyridoxine/pyridoxamine 5'-phosphate oxidase HAMAP MF_01629
EC=1.4.3.5 HAMAP MF_01629
Alternative name(s):
PNP/PMP oxidase HAMAP MF_01629
Pyridoxal 5'-phosphate synthase HAMAP MF_01629
Gene names
Name:pdxH HAMAP MF_01629
ORF Names:BAEG_00749 EMBL EEY29441.1
OrganismBrucella suis bv. 5 str. 513 EMBL EEY29441.1
Taxonomic identifier520489 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Brucellaceae › Brucella

Protein attributes

Sequence length208 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) By similarity. HAMAP MF_01629 SAAS SAAS019740

Catalytic activity

Pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + H2O2. HAMAP MF_01629 SAAS SAAS019740

Pyridoxine 5'-phosphate + O2 = pyridoxal 5'-phosphate + H2O2. HAMAP MF_01629 SAAS SAAS019740

Cofactor

Binds 1 FMN per subunit By similarity. HAMAP MF_01629 SAAS SAAS019740

Pathway

Cofactor biosynthesis; B6 vitamer interconversion; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1. HAMAP MF_01629 SAAS SAAS019740

Cofactor biosynthesis; B6 vitamer interconversion; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1. HAMAP MF_01629 SAAS SAAS019740

Subunit structure

Homodimer By similarity. HAMAP MF_01629 SAAS SAAS019740

Sequence similarities

Belongs to the pyridoxamine 5'-phosphate oxidase family. HAMAP MF_01629

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding70 – 712FMN By similarity HAMAP MF_01629
Nucleotide binding134 – 1352FMN By similarity HAMAP MF_01629
Region185 – 1873Substrate binding By similarity HAMAP MF_01629

Sites

Binding site551FMN By similarity HAMAP MF_01629
Binding site581FMN; via amide nitrogen By similarity HAMAP MF_01629
Binding site601Substrate By similarity HAMAP MF_01629
Binding site771FMN By similarity HAMAP MF_01629
Binding site1171Substrate By similarity HAMAP MF_01629
Binding site1211Substrate By similarity HAMAP MF_01629
Binding site1251Substrate By similarity HAMAP MF_01629

Sequences

Sequence LengthMass (Da)Tools
D0PBB7 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: CB1F50BC9612DE28

FASTA20823,866
        10         20         30         40         50         60 
MEPVKMTNSS DDFTQSAEPF KLFAEWLADA AKSEPNDPNA VALATVDPDG LPNVRMVLLK 

        70         80         90        100        110        120 
DFDETGFVFY TNYESKKGQE ILSAEKAAMC FHWKSLRRQV RVRGPVEKVS DAEADAYYAS 

       130        140        150        160        170        180 
RPRGSRIGAW ASKQSRPLES RFALEKAVAE YTAKYAIGDI PRPPYWSGFR IRPVSIEFWH 

       190        200 
DRPFRLHDRV LFTRPTPEGD WNKDRLYP

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		DS999724 Genomic DNA. Translation: EEY29441.1.

3D structure databases

ProteinModelPortalD0PBB7.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

OMAHWSGFRI.

Family and domain databases

HAMAPMF_01629. PdxH.
[Tree]
InterProIPR000659. Pyridox_Oxase.
IPR019740. Pyridox_Oxase_CS.
IPR011576. Pyridox_Oxase_FMN-bd.
IPR019576. Pyridoxamine_oxidase_dimer_C.
IPR012349. Split_barrel_FMN-bd.
IPR009002. Split_barrel_FMN-bd-related.
[Graphical view]
Gene3DG3DSA:2.30.110.10. PNPOx_FMN_bd. 1 hit.
PANTHERPTHR10851. Pyridox_oxidase. 1 hit.
PfamPF10590. PNPOx_C. 1 hit.
PF01243. Pyridox_oxidase. 1 hit.
[Graphical view]
PIRSFPIRSF000190. Pyd_amn-ph_oxd. 1 hit.
SUPFAMSSF50475. FMN_binding. 1 hit.
TIGRFAMsTIGR00558. PdxH. 1 hit.
PROSITEPS01064. PYRIDOX_OXIDASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0PBB7_BRUSS
AccessionPrimary (citable) accession number: D0PBB7
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: December 14, 2011
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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