D0MXT4 (D0MXT4_PHYIT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA ligase RuleBase RU000617
EC=6.5.1.1 RuleBase RU000617

Gene names

ORF Names:

PITG_03514 EMBL EEY65982.1

Organism

Phytophthora infestans (strain T30-4) (Potato late blight fungus) [Reference proteome]

Taxonomic identifier

403677 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Stramenopiles › Oomycetes › Peronosporales › Phytophthora › Phytophthora infestans

Protein attributes

Sequence length	971 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). RuleBase RU000617
Sequence similarities	Belongs to the ATP-dependent DNA ligase family. RuleBase RU004196

Ontologies

Keywords
Biological process	DNA damage DNA recombination RuleBase RU000617 DNA repair RuleBase RU000617 DNA replication RuleBase RU000617
Ligand	ATP-binding RuleBase RU000617 Nucleotide-binding
Molecular function	Ligase RuleBase RU000617 EMBL EEY65982.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	DNA ligation involved in DNA repair Inferred from electronic annotation. Source: InterPro DNA recombination Inferred from electronic annotation. Source: UniProtKB-KW DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW DNA binding Inferred from electronic annotation. Source: InterPro DNA ligase (ATP) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D0MXT4 [UniParc]. Last modified December 15, 2009. Version 1. Checksum: B36315463F7AD926	FASTA	971	109,708
	10 20 30 40 50 60 MASVEDAALD QSAALGLSFT ALCSVLKAVE ATRKNDSKLD MLFSSSLRAQ VGGGDLYPLI 70 80 90 100 110 120 RLVLPQLDRE RTYMLKEKKI AKIYIDVLGL APISKDAQKL EHFNDPKIVD SKSVGDFAAV 130 140 150 160 170 180 LFDVVLYQSA RTKSKTHHTL EDVNTLLDRL VQADNNAARK KVFMKLATEY SADEQKWIIR 190 200 210 220 230 240 VILKDLKIGL RHERVLKFIH PDAMEMYNHT NDLHKVCKEL RNSAVRYVPQ LEPFQVFTPM 250 260 270 280 290 300 LAKRVNFGEC ISAINADAFV MEPKLDGERI TCHVQGKEVQ FISRNGINYT ENYAPSIKPH 310 320 330 340 350 360 VLSQLEPGID CILDGEMMVW DNTEYRLREF GLLKNTANAV RKGEATNRWL CYVVWDVVYV 370 380 390 400 410 420 GGGPKAEQLI REVFKDPGEI SAVMGLPLHA RRKLLLRILK PLDHRIIIIE QKLVNDKSAK 430 440 450 460 470 480 ERHEKVMAEV DQQVSNGGEG VIMKDLNAHY MCGESSRKAK KWLKLKPDYA GMTTDLDVII 490 500 510 520 530 540 VGGFYGTGRR RSGNVSVFLL GVLAHSLDEK KAAEATKPGA ACPVVYTFAK VGTGYNLEEL 550 560 570 580 590 600 EQMRQELEPY WQPWDDDNVP SHLNGWKPQK SDLRPDVWID PRHSKILEVY GFELSFTTLY 610 620 630 640 650 660 QTGLTIRFPR CKAIRNDKEW YQCIDLQDLN AARGSLSTKR ASEVALGQKS ATKRIKKRQT 670 680 690 700 710 720 VSARRPNGVL QDYSRADLEG IEQERNVFEG MEFCVLPGKY QKPPQDLASS FPDGIFEKNA 730 740 750 760 770 780 MQLSKQTVEK LLHSFGGAIV QNPIAGSTHY VVAAGDSGFK VVNLKKQGLF NVVHIRWVFN 790 800 810 820 830 840 CIVASRLVSL KAGDFISATD LQRQLLAKEY DRYGDHFTEH VTPDDLRRIL QELSSASERK 850 860 870 880 890 900 HTSLPWQFKL KELEMEEAEA MDSAFTFLAH CVVYFHNSSS SEDKDIDVLA MGQMKLIEQQ 910 920 930 940 950 960 LKLYGGVVAR EIDSSATHVV ADPAQVEQLA PAIRNLRHQG LPEPRVVTKE WVQECVEQRT 970 QVPDNNFVVH V

References

[1]

"Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans." The Broad Institute Genome Sequencing Platform Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M., Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O., Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A., Baxter L., Beynon J. , Boevink P.C., Bollmann S.R., Bos J.I., Bulone V., Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S., Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S., Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K., Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D., Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L., Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J., Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M., Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S., Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D., Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J., Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S., Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P., Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S., Nusbaum C. Nature 461:393-398(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: T30-4.

Cross-references

Sequence databases
EMBL GenBank DDBJ	DS028121 Genomic DNA. Translation: EEY65982.1.
RefSeq	XP_002906581.1. XM_002906535.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	PITG_03514T0; PITG_03514T0; PITG_03514.
GeneID	9467476.
KEGG	pif:PITG_03514.
Phylogenomic databases
HOGENOM	HOG000179646.
KO	K10777.
Family and domain databases
Gene3D	1.10.3260.10. 1 hit. 2.40.50.140. 1 hit.
InterPro	IPR001357. BRCT_dom. IPR000977. DNA_ligase_ATP-dep. IPR012309. DNA_ligase_ATP-dep_C. IPR012310. DNA_ligase_ATP-dep_cent. IPR016059. DNA_ligase_ATP-dep_CS. IPR012308. DNA_ligase_ATP-dep_N. IPR012340. NA-bd_OB-fold. [Graphical view]
Pfam	PF04679. DNA_ligase_A_C. 1 hit. PF01068. DNA_ligase_A_M. 1 hit. PF04675. DNA_ligase_A_N. 1 hit. [Graphical view]
SMART	SM00292. BRCT. 2 hits. [Graphical view]
SUPFAM	SSF52113. BRCT. 2 hits. SSF50249. Nucleic_acid_OB. 1 hit.
TIGRFAMs	TIGR00574. dnl1. 1 hit.
PROSITE	PS50172. BRCT. 2 hits. PS00697. DNA_LIGASE_A1. 1 hit. PS50160. DNA_LIGASE_A3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D0MXT4_PHYIT

Accession

Primary (citable) accession number: D0MXT4

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2009
Last sequence update:	December 15, 2009
Last modified:	March 6, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)