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D0MXT4

- D0MXT4_PHYIT

UniProt

D0MXT4 - D0MXT4_PHYIT

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Protein

DNA ligase

Gene
PITG_03514
Organism
Phytophthora infestans (strain T30-4) (Potato late blight fungus)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. DNA binding Source: InterPro
  3. DNA ligase (ATP) activity Source: UniProtKB-EC

GO - Biological processi

  1. DNA ligation involved in DNA repair Source: InterPro
  2. DNA recombination Source: UniProtKB-KW
  3. DNA replication Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Biological processi

DNA damage, DNA recombinationUniRule annotation, DNA repairUniRule annotation, DNA replicationUniRule annotation

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
DNA ligaseUniRule annotation (EC:6.5.1.1UniRule annotation)
Gene namesi
ORF Names:PITG_03514Imported
OrganismiPhytophthora infestans (strain T30-4) (Potato late blight fungus)
Taxonomic identifieri403677 [NCBI]
Taxonomic lineageiEukaryotaStramenopilesOomycetesPeronosporalesPhytophthora
ProteomesiUP000006643: Partially assembled WGS sequence

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000179646.
KOiK10777.
OMAiHMCPSTK.

Family and domain databases

Gene3Di1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProiIPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamiPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SMARTiSM00292. BRCT. 2 hits.
[Graphical view]
SUPFAMiSSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsiTIGR00574. dnl1. 1 hit.
PROSITEiPS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0MXT4-1 [UniParc]FASTAAdd to Basket

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MASVEDAALD QSAALGLSFT ALCSVLKAVE ATRKNDSKLD MLFSSSLRAQ    50
VGGGDLYPLI RLVLPQLDRE RTYMLKEKKI AKIYIDVLGL APISKDAQKL 100
EHFNDPKIVD SKSVGDFAAV LFDVVLYQSA RTKSKTHHTL EDVNTLLDRL 150
VQADNNAARK KVFMKLATEY SADEQKWIIR VILKDLKIGL RHERVLKFIH 200
PDAMEMYNHT NDLHKVCKEL RNSAVRYVPQ LEPFQVFTPM LAKRVNFGEC 250
ISAINADAFV MEPKLDGERI TCHVQGKEVQ FISRNGINYT ENYAPSIKPH 300
VLSQLEPGID CILDGEMMVW DNTEYRLREF GLLKNTANAV RKGEATNRWL 350
CYVVWDVVYV GGGPKAEQLI REVFKDPGEI SAVMGLPLHA RRKLLLRILK 400
PLDHRIIIIE QKLVNDKSAK ERHEKVMAEV DQQVSNGGEG VIMKDLNAHY 450
MCGESSRKAK KWLKLKPDYA GMTTDLDVII VGGFYGTGRR RSGNVSVFLL 500
GVLAHSLDEK KAAEATKPGA ACPVVYTFAK VGTGYNLEEL EQMRQELEPY 550
WQPWDDDNVP SHLNGWKPQK SDLRPDVWID PRHSKILEVY GFELSFTTLY 600
QTGLTIRFPR CKAIRNDKEW YQCIDLQDLN AARGSLSTKR ASEVALGQKS 650
ATKRIKKRQT VSARRPNGVL QDYSRADLEG IEQERNVFEG MEFCVLPGKY 700
QKPPQDLASS FPDGIFEKNA MQLSKQTVEK LLHSFGGAIV QNPIAGSTHY 750
VVAAGDSGFK VVNLKKQGLF NVVHIRWVFN CIVASRLVSL KAGDFISATD 800
LQRQLLAKEY DRYGDHFTEH VTPDDLRRIL QELSSASERK HTSLPWQFKL 850
KELEMEEAEA MDSAFTFLAH CVVYFHNSSS SEDKDIDVLA MGQMKLIEQQ 900
LKLYGGVVAR EIDSSATHVV ADPAQVEQLA PAIRNLRHQG LPEPRVVTKE 950
WVQECVEQRT QVPDNNFVVH V 971
Length:971
Mass (Da):109,708
Last modified:December 15, 2009 - v1
Checksum:iB36315463F7AD926
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS028121 Genomic DNA. Translation: EEY65982.1.
RefSeqiXP_002906581.1. XM_002906535.1.

Genome annotation databases

EnsemblProtistsiPITG_03514T0; PITG_03514T0; PITG_03514.
GeneIDi9467476.
KEGGipif:PITG_03514.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
DS028121 Genomic DNA. Translation: EEY65982.1 .
RefSeqi XP_002906581.1. XM_002906535.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblProtistsi PITG_03514T0 ; PITG_03514T0 ; PITG_03514 .
GeneIDi 9467476.
KEGGi pif:PITG_03514.

Phylogenomic databases

HOGENOMi HOG000179646.
KOi K10777.
OMAi HMCPSTK.

Family and domain databases

Gene3Di 1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
3.40.50.10190. 2 hits.
InterProi IPR001357. BRCT_dom.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view ]
Pfami PF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view ]
SMARTi SM00292. BRCT. 2 hits.
[Graphical view ]
SUPFAMi SSF117018. SSF117018. 1 hit.
SSF50249. SSF50249. 1 hit.
SSF52113. SSF52113. 2 hits.
TIGRFAMsi TIGR00574. dnl1. 1 hit.
PROSITEi PS50172. BRCT. 2 hits.
PS00697. DNA_LIGASE_A1. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence and analysis of the Irish potato famine pathogen Phytophthora infestans."
    The Broad Institute Genome Sequencing Platform
    Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., Cano L.M., Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., Bozkurt T.O., Ah-Fong A.M., Alvarado L., Anderson V.L., Armstrong M.R., Avrova A., Baxter L., Beynon J.
    , Boevink P.C., Bollmann S.R., Bos J.I., Bulone V., Cai G., Cakir C., Carrington J.C., Chawner M., Conti L., Costanzo S., Ewan R., Fahlgren N., Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S., Green P.J., Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K., Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D., Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L., Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J., Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M., Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S., Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D., Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., Studholme D.J., Sykes S., Thines M., van de Vondervoort P.J., Phuntumart V., Wawra S., Weide R., Win J., Young C., Zhou S., Fry W., Meyers B.C., van West P., Ristaino J., Govers F., Birch P.R., Whisson S.C., Judelson H.S., Nusbaum C.
    Nature 461:393-398(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: T30-4.

Entry informationi

Entry nameiD0MXT4_PHYIT
AccessioniPrimary (citable) accession number: D0MXT4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: November 13, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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