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Protein

Nicotinate phosphoribosyltransferase

Gene

Rmar_0195

Organism
Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) (Rhodothermus obamensis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotationSAAS annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
  3. nicotinate phosphoribosyltransferase activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide salvage Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseImported, LigaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciRMAR518766:GJJ8-205-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotationSAAS annotation (EC:6.3.4.21UniRule annotationSAAS annotation)
Gene namesi
Ordered Locus Names:Rmar_0195Imported
OrganismiRhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) (Rhodothermus obamensis)Imported
Taxonomic identifieri518766 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidetes Order II. Incertae sedisRhodothermaceaeRhodothermus
ProteomesiUP000002221 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi518766.Rmar_0195.

Structurei

3D structure databases

ProteinModelPortaliD0MCZ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000001113.
KOiK00763.
OrthoDBiEOG6D2KVQ.

Family and domain databases

InterProiIPR007229. Nic_PRibTrfase-Fam.
IPR006405. Nic_PRibTrfase_pncB.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01513. NAPRTase_put. 1 hit.

Sequencei

Sequence statusi: Complete.

D0MCZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHWVTDENAV LFTDLYELTM LQAYYREGLD TAVATFDLFV RQTPGRNYLL
60 70 80 90 100
ACGLDTVLHY LETLHFTQEA LDYLASLGRF EPDFLDYLAR FRFTGDVYAV
110 120 130 140 150
PEGTPVFAGE PLLQVVAPIG QAQLIETFVL NQITFQTGIA SKASRVVQAA
160 170 180 190 200
QGRLVADFGA RRMHGADAAL KAVRAYYIAG IQATSLVLGG QMFGVPVTGT
210 220 230 240 250
MAHSYVEAHP TEEDAFRAFA GLYPGTTLLV DTYDTLEGVR KVIALCKEQG
260 270 280 290 300
DRFQVGAIRI DSGDLAALAK EARRMLDEAG LTHIKIFASG SLDEYRIAEL
310 320 330 340 350
LAQGAPIDGF GVGTRMGTIS DRPYLDSAYK LSEFEGEGRM KLSLEKANLP
360 370 380 390 400
GRKQVFRFYG EDGRATHDVI ACHDEQLEGG EPLLHCVMRG GRRTEAGRDT
410 420 430 440 450
LEAARERARQ DLARLPERLL ALEEADPPYP VHISERLQTL GEAVRHRLMQ

QET
Length:453
Mass (Da):50,114
Last modified:December 15, 2009 - v1
Checksum:i06B1FA49EF0D5021
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001807 Genomic DNA. Translation: ACY47101.1.
RefSeqiYP_003289489.1. NC_013501.1.

Genome annotation databases

EnsemblBacteriaiACY47101; ACY47101; Rmar_0195.
KEGGirmr:Rmar_0195.
PATRICi32314403. VBIRhoMar93821_0190.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001807 Genomic DNA. Translation: ACY47101.1.
RefSeqiYP_003289489.1. NC_013501.1.

3D structure databases

ProteinModelPortaliD0MCZ1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi518766.Rmar_0195.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACY47101; ACY47101; Rmar_0195.
KEGGirmr:Rmar_0195.
PATRICi32314403. VBIRhoMar93821_0190.

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000001113.
KOiK00763.
OrthoDBiEOG6D2KVQ.

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457.
BioCyciRMAR518766:GJJ8-205-MONOMER.

Family and domain databases

InterProiIPR007229. Nic_PRibTrfase-Fam.
IPR006405. Nic_PRibTrfase_pncB.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01513. NAPRTase_put. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43812 / DSM 4252 / R-10Imported.

Entry informationi

Entry nameiD0MCZ1_RHOM4
AccessioniPrimary (citable) accession number: D0MCZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: April 29, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.