Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Nicotinate phosphoribosyltransferase

Gene

Rmar_0195

Organism
Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) (Rhodothermus obamensis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.SAAS annotation

Pathwayi: NAD(+) biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate.SAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Nicotinate phosphoribosyltransferase (Rmar_0195)
This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate, the pathway NAD(+) biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseImported, LigaseSAAS annotation, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesisSAAS annotation

Enzyme and pathway databases

BioCyciRMAR518766:GJJ8-205-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseSAAS annotation (EC:6.3.4.21SAAS annotation)
Gene namesi
Ordered Locus Names:Rmar_0195Imported
OrganismiRhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) (Rhodothermus obamensis)Imported
Taxonomic identifieri518766 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesBacteroidetes Order II. Incertae sedisRhodothermaceaeRhodothermus
Proteomesi
  • UP000002221 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi518766.Rmar_0195.

Structurei

3D structure databases

ProteinModelPortaliD0MCZ1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini139 – 313175QRPTase_CInterPro annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili398 – 42528Sequence analysisAdd
BLAST

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4107QI7. Bacteria.
COG1488. LUCA.
HOGENOMiHOG000001113.
KOiK00763.
OMAiGTANRKC.
OrthoDBiEOG6D2KVQ.

Family and domain databases

InterProiIPR007229. Nic_PRibTrfase-Fam.
IPR006405. Nic_PRibTrfase_pncB.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF01729. QRPTase_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01513. NAPRTase_put. 1 hit.

Sequencei

Sequence statusi: Complete.

D0MCZ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHWVTDENAV LFTDLYELTM LQAYYREGLD TAVATFDLFV RQTPGRNYLL
60 70 80 90 100
ACGLDTVLHY LETLHFTQEA LDYLASLGRF EPDFLDYLAR FRFTGDVYAV
110 120 130 140 150
PEGTPVFAGE PLLQVVAPIG QAQLIETFVL NQITFQTGIA SKASRVVQAA
160 170 180 190 200
QGRLVADFGA RRMHGADAAL KAVRAYYIAG IQATSLVLGG QMFGVPVTGT
210 220 230 240 250
MAHSYVEAHP TEEDAFRAFA GLYPGTTLLV DTYDTLEGVR KVIALCKEQG
260 270 280 290 300
DRFQVGAIRI DSGDLAALAK EARRMLDEAG LTHIKIFASG SLDEYRIAEL
310 320 330 340 350
LAQGAPIDGF GVGTRMGTIS DRPYLDSAYK LSEFEGEGRM KLSLEKANLP
360 370 380 390 400
GRKQVFRFYG EDGRATHDVI ACHDEQLEGG EPLLHCVMRG GRRTEAGRDT
410 420 430 440 450
LEAARERARQ DLARLPERLL ALEEADPPYP VHISERLQTL GEAVRHRLMQ

QET
Length:453
Mass (Da):50,114
Last modified:December 15, 2009 - v1
Checksum:i06B1FA49EF0D5021
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001807 Genomic DNA. Translation: ACY47101.1.
RefSeqiWP_012842713.1. NC_013501.1.

Genome annotation databases

EnsemblBacteriaiACY47101; ACY47101; Rmar_0195.
KEGGirmr:Rmar_0195.
PATRICi32314403. VBIRhoMar93821_0190.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001807 Genomic DNA. Translation: ACY47101.1.
RefSeqiWP_012842713.1. NC_013501.1.

3D structure databases

ProteinModelPortaliD0MCZ1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi518766.Rmar_0195.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACY47101; ACY47101; Rmar_0195.
KEGGirmr:Rmar_0195.
PATRICi32314403. VBIRhoMar93821_0190.

Phylogenomic databases

eggNOGiENOG4107QI7. Bacteria.
COG1488. LUCA.
HOGENOMiHOG000001113.
KOiK00763.
OMAiGTANRKC.
OrthoDBiEOG6D2KVQ.

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457.
BioCyciRMAR518766:GJJ8-205-MONOMER.

Family and domain databases

InterProiIPR007229. Nic_PRibTrfase-Fam.
IPR006405. Nic_PRibTrfase_pncB.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF01729. QRPTase_C. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01513. NAPRTase_put. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 43812 / DSM 4252 / R-10Imported.

Entry informationi

Entry nameiD0MCZ1_RHOM4
AccessioniPrimary (citable) accession number: D0MCZ1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: March 16, 2016
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.