D0MCT3 (D0MCT3_RHOM4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
D-alanine--D-alanine ligase EMBL ACY47043.1
EC=6.3.2.4 EMBL ACY47043.1

Gene names

Ordered Locus Names:

Rmar_0135 EMBL ACY47043.1

Organism

Rhodothermus marinus (strain ATCC 43812 / DSM 4252 / R-10) (Rhodothermus obamensis) [Complete proteome] [HAMAP] EMBL ACY47043.1

Taxonomic identifier

518766 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Bacteroidetes/Chlorobi group › Bacteroidetes › Bacteroidetes Order II. Incertae sedis › Rhodothermaceae › Rhodothermus › Rhodothermus marinus

Protein attributes

Sequence length	336 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Cell wall formation By similarity. SAAS SAAS005905
Catalytic activity	ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine. SAAS SAAS005905
Cofactor	Binds 2 magnesium or manganese ions per subunit By similarity. SAAS SAAS005905
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. SAAS SAAS005905
Subcellular location	Cytoplasm By similarity SAAS SAAS005905.
Sequence similarities	Contains 1 ATP-grasp domain. SAAS SAAS005905

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation SAAS SAAS005905 Peptidoglycan synthesis SAAS SAAS005905
Cellular component	Cytoplasm SAAS SAAS005905
Ligand	ATP-binding SAAS SAAS005905 Magnesium SAAS SAAS005905 Manganese SAAS SAAS005905 Metal-binding SAAS SAAS005905 Nucleotide-binding
Molecular function	Ligase SAAS SAAS005905 EMBL ACY47043.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	peptidoglycan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW D-alanine-D-alanine ligase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D0MCT3 [UniParc]. Last modified December 15, 2009. Version 1. Checksum: 77C050818A9843E9	FASTA	336	37,128
	10 20 30 40 50 60 MHPNGLMRIG IVYDLFDDYP WEVGEPPDAD AENEPPETVD VLAAAIRKLG HKPVRIGTAY 70 80 90 100 110 120 DLLVELPDLR IDCGISIAEG ARGRNREAYA PMLFEMAGIP YIGSDPLTLS LSLDKAWTKD 130 140 150 160 170 180 LVAAAGVPTP PYRTYAGPED VDPHDLPGPF PLFVKPRYEG SSKGITAASK VHSLEALREQ 190 200 210 220 230 240 VARLTATYRQ EVIVEPFIEG SEFTVAVIGN NPPEPLPVLQ RAVEATTGIG LHALEHRGMK 250 260 270 280 290 300 PAAALEAAPY VPLTDELERC LQQLAVRVYE KLQCRDFARL DFRVDREGKP WFLEINPLPT 310 320 330 FAPDGTFAIL AELMQRPYVE FLAEILQRGL RRLGLA

References

[1]

"Complete genome sequence of Rhodothermus marinus type strain (R-10)." Nolan M., Tindall B.J., Pomrenke H., Lapidus A., Copeland A., Glavina Del Rio T., Lucas S., Chen F., Tice H., Cheng J.-F., Saunders E., Han C., Bruce D., Goodwin L., Chain P., Pitluck S., Pati A., Ivanova N. , Mavromatis K., Chen A., Palaniappan K., Land M., Hauser L., Chang Y.-J., Jeffries C.D., Brettin T., Goeker M., Bristow J., Eisen J.A., Markowitz V., Hugenholtz P., Kyrpides N.C., Klenk H.-P., Detter J.C. Stand. Genomic Sci. 1:283-290(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 43812 / DSM 4252 / R-10.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001807 Genomic DNA. Translation: ACY47043.1.
RefSeq	YP_003289431.1. NC_013501.1.
3D structure databases
ProteinModelPortal	D0MCT3.
ModBase	Search...
Protein-protein interaction databases
STRING	518766.Rmar_0135.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACY47043; ACY47043; Rmar_0135.
GeneID	8566760.
KEGG	rmr:Rmar_0135.
PATRIC	32314281. VBIRhoMar93821_0134.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1181.
HOGENOM	HOG000011592.
KO	K01921.
Enzyme and pathway databases
BioCyc	RMAR518766:GJJ8-140-MONOMER.
UniPathway	UPA00219.
Family and domain databases
Gene3D	3.30.1490.20. 1 hit. 3.30.470.20. 2 hits.
InterPro	IPR011761. ATP-grasp. IPR013815. ATP_grasp_subdomain_1. IPR013816. ATP_grasp_subdomain_2. IPR005905. D_ala_D_ala. IPR011095. Dala_Dala_lig_C. IPR016185. PreATP-grasp_dom. [Graphical view]
PANTHER	PTHR23132. PTHR23132. 1 hit.
Pfam	PF07478. Dala_Dala_lig_C. 1 hit. [Graphical view]
SUPFAM	SSF52440. PreATP-grasp-like. 1 hit.
PROSITE	PS50975. ATP_GRASP. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D0MCT3_RHOM4

Accession

Primary (citable) accession number: D0MCT3

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2009
Last sequence update:	December 15, 2009
Last modified:	May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)