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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Vibrio sp. (strain Ex25)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei138 – 1381UniRule annotation
Active sitei544 – 5441UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciVSP150340:GJJG-758-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:VEA_002310Imported
OrganismiVibrio sp. (strain Ex25)Imported
Taxonomic identifieri150340 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio
ProteomesiUP000002571 Componenti: Chromosome 1

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi150340.VEA_002310.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0M6D1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNEKYAALKS NVRMLGHLLG NTIRDAHGEE IFEKVETIRK LSKSAQAGNQ
60 70 80 90 100
ADRDSLIEEI KHLPDEQLTP VTRAFNQFLN LTNIAEQYHT ISRHCEEHIC
110 120 130 140 150
EPDAINSLFS KLVQNDVSKL DTAQAVRDLN IELVLTAHPT EITRRTMINK
160 170 180 190 200
LVKINECLSK LELSDLSSKE RKKTERRLEQ LIAQSWHSDV IRQQRPTPLD
210 220 230 240 250
EAKWGFAVVE NSLWEAVPDF LREMHDRLKS YLGEGLPIDA RPVHFSSWMG
260 270 280 290 300
GDRDGNPFVT HSVTREVLLL SRWKAADLYL NDINELISEL SMTVSNDQVR
310 320 330 340 350
ELAGEDQHEP YRAILKQLRT LLNETKDILD AKIHGQKLAV KAPLQKVEQL
360 370 380 390 400
WEPLYACYQS LNECGMGVIA NGSLLDTLRR VKAFGIHLVR LDIRQESTRH
410 420 430 440 450
SDVLSELTRY LGIGDYEQWS EQDKIAFLTN ELASKRPLLP RDWEPSEPVK
460 470 480 490 500
EVLDTCKIIA AQPREAFGAY VISMARTASD VLAVHLLLQE AGCPYRMDVC
510 520 530 540 550
PLFETLDDLN NAESVIKQLM GIDLYRGFIQ NHQMVMIGYS DSAKDAGVMS
560 570 580 590 600
AGWAQYHAME SLVKVAEEEG VELTLFHGRG GTVGRGGAPA HAALLSQPPK
610 620 630 640 650
SLKGGLRVTE QGEMIRFKLG LPDVAVNSFN LYASAILEAN LLPPPEPKQE
660 670 680 690 700
WRDLMEVLSE VSCESYRNVV RGEPDFVPYF RQATPELELG KLPLGSRPAK
710 720 730 740 750
RNPKGGVESL RAIPWIFSWS QNRLVLPAWL GAGEAIQYSI DKGHQALLEE
760 770 780 790 800
MCREWPFFST RLGMLEMVYS KCNIDISRYY DERLVDESLR PLGEKLRAQL
810 820 830 840 850
QEDIKAVLNV ENNENLMQHD PWGLESIRLR NIYVEPLNML QAELLYRTRQ
860 870
TEEASANLEE ALMVTIAGIA AGMRNTG
Length:877
Mass (Da):99,255
Last modified:December 15, 2009 - v1
Checksum:iB1149A59D4C58BD6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001805 Genomic DNA. Translation: ACY50472.1.
RefSeqiWP_012841346.1. NC_013456.1.
YP_003284937.1. NC_013456.1.

Genome annotation databases

EnsemblBacteriaiACY50472; ACY50472; VEA_002310.
KEGGivex:VEA_002310.
PATRICi32534561. VBIVibSp203755_0701.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001805 Genomic DNA. Translation: ACY50472.1.
RefSeqiWP_012841346.1. NC_013456.1.
YP_003284937.1. NC_013456.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi150340.VEA_002310.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACY50472; ACY50472; VEA_002310.
KEGGivex:VEA_002310.
PATRICi32534561. VBIVibSp203755_0701.

Phylogenomic databases

HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciVSP150340:GJJG-758-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Sequence of the deep-sea isolate Vibrio sp. strain Ex25."
    Munk A.C., Tapia R., Green L., Rogers Y., Detter J.C., Bruce D., Brettin T.S., Colwell R., Huq A., Grim C.J., Hasan N.A., Vonstein V., Bartels D.
    Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ex25Imported.

Entry informationi

Entry nameiD0M6D1_VIBSE
AccessioniPrimary (citable) accession number: D0M6D1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: April 1, 2015
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.