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D0M4F5 (D0M4F5_VIBSE) Unreviewed, UniProtKB/TrEMBL

Last modified June 11, 2014. Version 30. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Thymidine kinase HAMAP-Rule MF_00124 RuleBase RU000544

EC=2.7.1.21 HAMAP-Rule MF_00124 RuleBase RU000544
Gene names
Name:tdk HAMAP-Rule MF_00124
Ordered Locus Names:VEA_003836 EMBL ACY51996.1
OrganismVibrio sp. (strain Ex25) [Complete proteome] [HAMAP] EMBL ACY51996.1
Taxonomic identifier150340 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeVibrio

Protein attributes

Sequence length192 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + thymidine = ADP + thymidine 5'-phosphate. HAMAP-Rule MF_00124 RuleBase RU000544 SAAS SAAS020634

Subunit structure

Homotetramer By similarity. HAMAP-Rule MF_00124 SAAS SAAS020634

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00124 SAAS SAAS020634.

Sequence similarities

Belongs to the thymidine kinase family. HAMAP-Rule MF_00124

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding9 – 168ATP By similarity HAMAP-Rule MF_00124
Nucleotide binding87 – 904ATP By similarity HAMAP-Rule MF_00124

Sites

Active site881Proton acceptor By similarity HAMAP-Rule MF_00124
Metal binding1451Zinc By similarity HAMAP-Rule MF_00124
Metal binding1471Zinc By similarity HAMAP-Rule MF_00124
Metal binding1821Zinc By similarity HAMAP-Rule MF_00124
Metal binding1851Zinc By similarity HAMAP-Rule MF_00124

Sequences

Sequence LengthMass (Da)Tools
D0M4F5 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: 2E51D744123E3783

FASTA19221,775
        10         20         30         40         50         60 
MAQMYFYYSA MNAGKSTTLL QSSFNYQERG MTPVIFTAAL DDRFGVGKVS SRIGLQSDAH 

        70         80         90        100        110        120 
LFRQDTNLYQ EIAALNEVEK RHCILVDECQ FLSKEQVYQL TEVVDKLHIP VLCYGLRTDF 

       130        140        150        160        170        180 
LGELFEGSKY LLSWADKLVE LKTICHCGRK ANMVIRTDEH GVAIKEGDQV AIGGNDKYVS 

       190 
VCRQHYKEAL GK 

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References

[1]"Sequence of the deep-sea isolate Vibrio sp. strain Ex25."
Munk A.C., Tapia R., Green L., Rogers Y., Detter J.C., Bruce D., Brettin T.S., Colwell R., Huq A., Grim C.J., Hasan N.A., Vonstein V., Bartels D.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ex25.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001805 Genomic DNA. Translation: ACY51996.1.
RefSeqYP_003286461.1. NC_013456.1.

3D structure databases

ProteinModelPortalD0M4F5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING150340.VEA_003836.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACY51996; ACY51996; VEA_003836.
GeneID8557571.
KEGGvex:VEA_003836.
PATRIC32537725. VBIVibSp203755_2232.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1435.
HOGENOMHOG000076391.
KOK00857.
OMAELKTVCH.
OrthoDBEOG69D3J2.

Enzyme and pathway databases

BioCycVSP150340:GJJG-2334-MONOMER.

Family and domain databases

HAMAPMF_00124. Thymidine_kinase.
InterProIPR027417. P-loop_NTPase.
IPR001267. Thymidine_kinase.
IPR020633. Thymidine_kinase_CS.
IPR020634. Thymidine_kinase_subgr.
[Graphical view]
PANTHERPTHR11441. PTHR11441. 1 hit.
PfamPF00265. TK. 1 hit.
[Graphical view]
PIRSFPIRSF035805. TK_cell. 1 hit.
SUPFAMSSF52540. SSF52540. 1 hit.
PROSITEPS00603. TK_CELLULAR_TYPE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0M4F5_VIBSE
AccessionPrimary (citable) accession number: D0M4F5
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: June 11, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)