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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) (Rhodococcus bronchialis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei169 – 1691UniRule annotation
Active sitei607 – 6071UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciGBRO526226:GHJF-2399-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Gbro_2367Imported
OrganismiGordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) (Rhodococcus bronchialis)Imported
Taxonomic identifieri526226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeGordoniaceaeGordonia
ProteomesiUP000001219 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi526226.Gbro_2367.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0LCT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQSVPSRGA PAWRPSISIV DHITVDDEGR ALTEPLREDI RLLGGLLGDV
60 70 80 90 100
IREHSGDEVF ELVEAARVAA FRIRRNEIDR GELADMFSGV SLDVVMPVIR
110 120 130 140 150
AFSNFALLAN LAEDIHRERR RAIHLRAGDP PQDSSLAATY TKLAEAGLDD
160 170 180 190 200
EQVGRALADA TVVPVITAHP TETRRRSVFE AQNRITELMR YRSRSELTPA
210 220 230 240 250
EDDVVIKAIR RQILTLWQTA LIRLERLTIQ DEIRSGLRYY DASFFDVVPK
260 270 280 290 300
INTSVRASLR AAYPDAGLAD DPMIRMGSWI GGDRDGNPFV TDEIVEMATT
310 320 330 340 350
LAARTAIGHH LSELHKLAEE LSMSTRLMDP GEALYELAGV PADDPKADEP
360 370 380 390 400
FRLALRHIRS RLATTATEMF GEEVMKAADL FLVNGKPAYA DAAELLADLD
410 420 430 440 450
VIDAALRHGK DDILADDRLL TLRESVRTFG FNLSGLDMRQ NSDMHEEVIA
460 470 480 490 500
ELLAWAGVHP DYASLDEDER VAILSEELQK RRPLTRPDAD LSELAVKELG
510 520 530 540 550
IVRAAARAVA TFGPQAVPNY IISMCTSVSD MLEPMILLKE AGLIDIDAES
560 570 580 590 600
GTLTSTVRIV PLFETIEDLQ QGATTLLAAL DLPFYRGLVD SQAGMQEIML
610 620 630 640 650
GYSDSNKDGG YMAANWALYR GELDLVEAAA KAGIRLRLFH GRGGTVGRGG
660 670 680 690 700
GPSYDAILAQ PPGAVQGSLR ITEQGEIIAA KYAEPVSAER NLETLLAATI
710 720 730 740 750
ESSLLDVEGL GDDSEDAYAI MDELAALARS AYSKLVHDTP GFVEYFTTST
760 770 780 790 800
PLSEIGALNI GSRPASRKQT EKISDLRAIP WVLSWTQSRA MLPGWYGTGS
810 820 830 840 850
AFAEWIGDSD DRLATLQRYY TEWPFFRSVM SNMAQVLAKS DMNLAHRYAQ
860 870 880 890 900
LVPDEELRDK VFGMIVGEHE RTIAMYSKIT GTDDLLADNA ALKRSVYNRF
910 920 930 940
PYLEPLNLLQ VELLRRFRAG DDEPRIRRGI QLTMNGLATA LRNSG
Length:945
Mass (Da):104,194
Last modified:December 15, 2009 - v1
Checksum:iE94F28109F5A0BBC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001802 Genomic DNA. Translation: ACY21609.1.
RefSeqiYP_003273502.1. NC_013441.1.

Genome annotation databases

EnsemblBacteriaiACY21609; ACY21609; Gbro_2367.
KEGGigbr:Gbro_2367.
PATRICi32184347. VBIGorBro114338_2425.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001802 Genomic DNA. Translation: ACY21609.1.
RefSeqiYP_003273502.1. NC_013441.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi526226.Gbro_2367.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACY21609; ACY21609; Gbro_2367.
KEGGigbr:Gbro_2367.
PATRICi32184347. VBIGorBro114338_2425.

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiCGMGVIA.
OrthoDBiEOG6TJ7T8.

Enzyme and pathway databases

BioCyciGBRO526226:GHJF-2399-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667Imported.

Entry informationi

Entry nameiD0LCT8_GORB4
AccessioniPrimary (citable) accession number: D0LCT8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: April 29, 2015
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.