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D0LCT0

- D0LCT0_GORB4

UniProt

D0LCT0 - D0LCT0_GORB4

Protein

UvrABC system protein C

Gene

uvrC

Organism
Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) (Rhodococcus bronchialis)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 36 (01 Oct 2014)
      Sequence version 1 (15 Dec 2009)
      Previous versions | rss
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    Functioni

    The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.UniRule annotationSAAS annotation

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-HAMAP
    2. excinuclease ABC activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. nucleotide-excision repair Source: UniProtKB-HAMAP
    2. SOS response Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Excision nucleaseUniRule annotationSAAS annotation

    Keywords - Biological processi

    DNA damage, DNA excisionUniRule annotationSAAS annotation, DNA repair, SOS responseUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciGBRO526226:GHJF-2391-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    UvrABC system protein CUniRule annotation
    Short name:
    Protein UvrCUniRule annotation
    Alternative name(s):
    Excinuclease ABC subunit CUniRule annotation
    Gene namesi
    Name:uvrCUniRule annotation
    Ordered Locus Names:Gbro_2359Imported
    OrganismiGordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) (Rhodococcus bronchialis)Imported
    Taxonomic identifieri526226 [NCBI]
    Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeGordoniaceaeGordonia
    ProteomesiUP000001219: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. excinuclease repair complex Source: InterPro

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Interacts with UvrB in an incision complex.UniRule annotationSAAS annotation

    Protein-protein interaction databases

    STRINGi526226.Gbro_2359.

    Structurei

    3D structure databases

    ProteinModelPortaliD0LCT0.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini16 – 9580GIY-YIGUniRule annotationAdd
    BLAST
    Domaini208 – 24336UVRUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the UvrC family.UniRule annotation
    Contains 1 GIY-YIG domain.UniRule annotation
    Contains 1 UVR domain.UniRule annotation
    Contains GIY-YIG domain.SAAS annotation
    Contains UVR domain.SAAS annotation

    Phylogenomic databases

    eggNOGiCOG0322.
    HOGENOMiHOG000279962.
    KOiK03703.
    OMAiAMHEVIT.
    OrthoDBiEOG6K13R9.

    Family and domain databases

    Gene3Di3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPiMF_00203. UvrC.
    InterProiIPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view]
    PfamiPF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view]
    SMARTiSM00465. GIYc. 1 hit.
    SM00278. HhH1. 2 hits.
    [Graphical view]
    SUPFAMiSSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsiTIGR00194. uvrC. 1 hit.
    PROSITEiPS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D0LCT0-1 [UniParc]FASTAAdd to Basket

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    MADPTTYRPA PGTIPTEPGV YRFRDAHGRV IYVGKAKSLR SRLTSYFADI    50
    ASLHPRTRQM VTTAASVEWT VVGTEVEALQ LEYNWIKEFD PRFNVRYRDD 100
    KSYPMLAVTL NEEYPRLFVY RGPRRRGVRY FGPYSHAWAI RETVDLLTRV 150
    FPARTCSAGV FKRHRQIDRP CLLGYIDKCA APCVGRVSAE QHREIVDDFC 200
    DFLAGRTDQM IRRMEREMSA AATELDFERA ARLRDDIGAM RRAMEKQAVV 250
    LGDGTDADVV AFAGDDLEVS VQIFHVRDGR VRGQRGWVVE RSDNGSVGDL 300
    VGDFLTQFYG QQVDLDATVE IGAGRARGDA VPREVMVPEL PSDAAELEDW 350
    LSELRGSRVR LRVPQRGDKK ALFDTVGRNA SEALAQHKLR RAGDLTTRSA 400
    ALTELQESLG LDQAPLRIEC VDISHVQGTD VVASLVVFED GLPRKSDYRH 450
    YSIRHAAGDG HSDDVASIAE VTRRRFLRHR ADQLPAPPPM ESGPAPTGTP 500
    EADVAPPVPK KFAYPPNLFV VDGGAPQVHA AAAVLDELGI TDVSVIGLAK 550
    RLEEVWTPGD DEPIILPRAG EALFLLQRVR DEAHRFAITF HRNKRSKRMT 600
    ESVLDGVPGL GRTRKTALVT HFGSVARLRE ASLEDISGVP GIGMATARAV 650
    QAALGEDGRD DAADVSGGDG D 671
    Length:671
    Mass (Da):74,093
    Last modified:December 15, 2009 - v1
    Checksum:iEB4B09594D872B98
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001802 Genomic DNA. Translation: ACY21601.1.
    RefSeqiYP_003273494.1. NC_013441.1.

    Genome annotation databases

    EnsemblBacteriaiACY21601; ACY21601; Gbro_2359.
    GeneIDi8551722.
    KEGGigbr:Gbro_2359.
    PATRICi32184331. VBIGorBro114338_2417.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001802 Genomic DNA. Translation: ACY21601.1 .
    RefSeqi YP_003273494.1. NC_013441.1.

    3D structure databases

    ProteinModelPortali D0LCT0.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 526226.Gbro_2359.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACY21601 ; ACY21601 ; Gbro_2359 .
    GeneIDi 8551722.
    KEGGi gbr:Gbro_2359.
    PATRICi 32184331. VBIGorBro114338_2417.

    Phylogenomic databases

    eggNOGi COG0322.
    HOGENOMi HOG000279962.
    KOi K03703.
    OMAi AMHEVIT.
    OrthoDBi EOG6K13R9.

    Enzyme and pathway databases

    BioCyci GBRO526226:GHJF-2391-MONOMER.

    Family and domain databases

    Gene3Di 3.40.1440.10. 1 hit.
    4.10.860.10. 1 hit.
    HAMAPi MF_00203. UvrC.
    InterProi IPR027299. GIY-YIG_dom.
    IPR000305. GIY-YIG_SF.
    IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
    IPR010994. RuvA_2-like.
    IPR001943. UVR_dom.
    IPR004791. UvrC.
    IPR001162. UvrC_homol_region.
    [Graphical view ]
    Pfami PF01541. GIY-YIG. 1 hit.
    PF02151. UVR. 1 hit.
    PF08459. UvrC_HhH_N. 1 hit.
    [Graphical view ]
    SMARTi SM00465. GIYc. 1 hit.
    SM00278. HhH1. 2 hits.
    [Graphical view ]
    SUPFAMi SSF46600. SSF46600. 1 hit.
    SSF47781. SSF47781. 1 hit.
    SSF82771. SSF82771. 1 hit.
    TIGRFAMsi TIGR00194. uvrC. 1 hit.
    PROSITEi PS50164. GIY_YIG. 1 hit.
    PS50151. UVR. 1 hit.
    PS50165. UVRC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667Imported.

    Entry informationi

    Entry nameiD0LCT0_GORB4
    AccessioniPrimary (citable) accession number: D0LCT0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2009
    Last sequence update: December 15, 2009
    Last modified: October 1, 2014
    This is version 36 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3