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D0LCT0 (D0LCT0_GORB4) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UvrABC system protein C HAMAP-Rule MF_00203

Short name=Protein UvrC HAMAP-Rule MF_00203
Alternative name(s):
Excinuclease ABC subunit C HAMAP-Rule MF_00203
Gene names
Name:uvrC HAMAP-Rule MF_00203
Ordered Locus Names:Gbro_2359 EMBL ACY21601.1
OrganismGordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) (Rhodococcus bronchialis) [Complete proteome] [HAMAP] EMBL ACY21601.1
Taxonomic identifier526226 [NCBI]
Taxonomic lineageBacteriaActinobacteriaActinobacteridaeActinomycetalesCorynebacterineaeGordoniaceaeGordonia

Protein attributes

Sequence length671 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity. HAMAP-Rule MF_00203 SAAS SAAS027299

Subunit structure

Interacts with UvrB in an incision complex By similarity. HAMAP-Rule MF_00203 SAAS SAAS027299

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00203 SAAS SAAS027299.

Sequence similarities

Belongs to the UvrC family. HAMAP-Rule MF_00203

Contains 1 GIY-YIG domain. HAMAP-Rule MF_00203

Contains 1 UVR domain. HAMAP-Rule MF_00203

Contains GIY-YIG domain. SAAS SAAS027299

Contains UVR domain. SAAS SAAS027299

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain16 – 9580GIY-YIG By similarity HAMAP-Rule MF_00203
Domain208 – 24336UVR By similarity HAMAP-Rule MF_00203

Sequences

Sequence LengthMass (Da)Tools
D0LCT0 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: EB4B09594D872B98

FASTA67174,093
        10         20         30         40         50         60 
MADPTTYRPA PGTIPTEPGV YRFRDAHGRV IYVGKAKSLR SRLTSYFADI ASLHPRTRQM 

        70         80         90        100        110        120 
VTTAASVEWT VVGTEVEALQ LEYNWIKEFD PRFNVRYRDD KSYPMLAVTL NEEYPRLFVY 

       130        140        150        160        170        180 
RGPRRRGVRY FGPYSHAWAI RETVDLLTRV FPARTCSAGV FKRHRQIDRP CLLGYIDKCA 

       190        200        210        220        230        240 
APCVGRVSAE QHREIVDDFC DFLAGRTDQM IRRMEREMSA AATELDFERA ARLRDDIGAM 

       250        260        270        280        290        300 
RRAMEKQAVV LGDGTDADVV AFAGDDLEVS VQIFHVRDGR VRGQRGWVVE RSDNGSVGDL 

       310        320        330        340        350        360 
VGDFLTQFYG QQVDLDATVE IGAGRARGDA VPREVMVPEL PSDAAELEDW LSELRGSRVR 

       370        380        390        400        410        420 
LRVPQRGDKK ALFDTVGRNA SEALAQHKLR RAGDLTTRSA ALTELQESLG LDQAPLRIEC 

       430        440        450        460        470        480 
VDISHVQGTD VVASLVVFED GLPRKSDYRH YSIRHAAGDG HSDDVASIAE VTRRRFLRHR 

       490        500        510        520        530        540 
ADQLPAPPPM ESGPAPTGTP EADVAPPVPK KFAYPPNLFV VDGGAPQVHA AAAVLDELGI 

       550        560        570        580        590        600 
TDVSVIGLAK RLEEVWTPGD DEPIILPRAG EALFLLQRVR DEAHRFAITF HRNKRSKRMT 

       610        620        630        640        650        660 
ESVLDGVPGL GRTRKTALVT HFGSVARLRE ASLEDISGVP GIGMATARAV QAALGEDGRD 

       670 
DAADVSGGDG D 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001802 Genomic DNA. Translation: ACY21601.1.
RefSeqYP_003273494.1. NC_013441.1.

3D structure databases

ProteinModelPortalD0LCT0.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING526226.Gbro_2359.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACY21601; ACY21601; Gbro_2359.
GeneID8551722.
KEGGgbr:Gbro_2359.
PATRIC32184331. VBIGorBro114338_2417.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0322.
HOGENOMHOG000279962.
KOK03703.
OMAAMHEVIT.
OrthoDBEOG6K13R9.

Enzyme and pathway databases

BioCycGBRO526226:GHJF-2391-MONOMER.

Family and domain databases

Gene3D3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPMF_00203. UvrC.
InterProIPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view]
PfamPF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view]
SMARTSM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsTIGR00194. uvrC. 1 hit.
PROSITEPS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0LCT0_GORB4
AccessionPrimary (citable) accession number: D0LCT0
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: May 14, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)