D0L9Z1 (D0L9Z1_GORB4) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Indole-3-glycerol phosphate synthase HAMAP-Rule MF_00134
Short name=IGPS HAMAP-Rule MF_00134
EC=4.1.1.48 HAMAP-Rule MF_00134

Gene names

Name:	trpC HAMAP-Rule MF_00134
Ordered Locus Names:	Gbro_2948 EMBL ACY22156.1

Organism

Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) (Rhodococcus bronchialis) [Complete proteome] [HAMAP] EMBL ACY22156.1

Taxonomic identifier

526226 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Actinobacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Corynebacterineae › Gordoniaceae › Gordonia › Gordonia bronchialis

Protein attributes

Sequence length	272 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. SAAS SAAS001468 HAMAP-Rule MF_00134
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. SAAS SAAS001468 HAMAP-Rule MF_00134
Sequence similarities	Belongs to the TrpC family. HAMAP-Rule MF_00134

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis SAAS SAAS001468 HAMAP-Rule MF_00134
Molecular function	Decarboxylase SAAS SAAS001468 HAMAP-Rule MF_00134 Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D0L9Z1 [UniParc]. Last modified December 15, 2009. Version 1. Checksum: BEDC056B604E10D2	FASTA	272	28,171
	10 20 30 40 50 60 MSTPTVLDSI IEGVKADVAA REAVVDYAAV KAASAKAPAP RDALAALRKP GIGVIAEVKR 70 80 90 100 110 120 ASPSKGALAD IPDPAELATM YESAGARIIS VLTEERRFHG SLADLDSVRA AVDIPVLRKD 130 140 150 160 170 180 FIVGPYQIHE ARAHGADVIL LIVAALEQNV LAALLDRTES LGMTALVEVH TEEEASRALE 190 200 210 220 230 240 AGASVIGVNN RNLKTLEVDR DCFGRIAPGL PTETIRIAES GVRGTADLLA FAGAGADAVL 250 260 270 VGEALVTSGN PRAAVSELVT AGTHPSCPKP VR

References

[1]

"The complete chromosome of Gordonia bronchialis DSM 43247." US DOE Joint Genome Institute (JGI-PGF) Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Bruce D., Goodwin L., Pitluck S., Kyrpides N., Mavromatis K., Ivanova N., Ovchinnikova G., Saunders E., Brettin T., Detter J.C., Han C., Larimer F. , Land M., Hauser L., Markowitz V., Cheng J.-F., Hugenholtz P., Woyke T., Wu D., Jando M., Schneider S., Goeker M., Klenk H.-P., Eisen J.A. Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001802 Genomic DNA. Translation: ACY22156.1.
RefSeq	YP_003274049.1. NC_013441.1.
3D structure databases
ProteinModelPortal	D0L9Z1.
ModBase	Search...
Protein-protein interaction databases
STRING	526226.Gbro_2948.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ACY22156; ACY22156; Gbro_2948.
GeneID	8552317.
KEGG	gbr:Gbro_2948.
PATRIC	32185523. VBIGorBro114338_3007.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0134.
HOGENOM	HOG000230462.
KO	K01609.
OMA	YQAGGAR.
Enzyme and pathway databases
BioCyc	GBRO526226:GHJF-2980-MONOMER.
UniPathway	UPA00035; UER00043.
Family and domain databases
Gene3D	3.20.20.70. 1 hit.
HAMAP	MF_00134_B. IGPS_B.
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR001468. Indole-3-GlycerolPSynthase_CS. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
PROSITE	PS00614. IGPS. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D0L9Z1_GORB4

Accession

Primary (citable) accession number: D0L9Z1

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2009
Last sequence update:	December 15, 2009
Last modified:	May 29, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)