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Protein

Superoxide dismutase [Cu-Zn]

Gene

Gbro_0664

Organism
Gordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) (Rhodococcus bronchialis)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Destroys radicals which are normally produced within the cells and which are toxic to biological systems.UniRule annotation

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.UniRule annotation

Cofactori

Protein has several cofactor binding sites:
  • Cu cationUniRule annotationNote: Binds 1 copper ion per subunit.UniRule annotation
  • Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

CopperUniRule annotation, Metal-bindingUniRule annotation, ZincUniRule annotation

Enzyme and pathway databases

BioCyciGBRO526226:GHJF-675-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Cu-Zn]UniRule annotation (EC:1.15.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:Gbro_0664Imported
OrganismiGordonia bronchialis (strain ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667) (Rhodococcus bronchialis)Imported
Taxonomic identifieri526226 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesGordoniaceaeGordonia
ProteomesiUP000001219 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2929 PotentialImportedAdd
BLAST
Chaini30 – 218189 PotentialImportedPRO_5000527848Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi526226.Gbro_0664.

Structurei

3D structure databases

ProteinModelPortaliD0L2A2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Cu-Zn superoxide dismutase family.UniRule annotation

Keywords - Domaini

SignalImported

Phylogenomic databases

eggNOGiCOG2032.
HOGENOMiHOG000263448.
KOiK04565.
OMAiYNQTNGT.
OrthoDBiEOG6K13RS.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

D0L2A2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTATTHRPTT LRVIAALASA GAIGAVLAGC TPDEPPTDAK GTTPSVISGP
60 70 80 90 100
PLPPGSVQNE DDVPTGQQAK AEIKNPDGEV VGEATFTARN PDGPVTVNVR
110 120 130 140 150
VTGGDIAPGF HGMHIHANGQ CAPKDGEDFG AAGGHLQVGA ANAHPSSGDL
160 170 180 190 200
VSINILNDHT GETVTTTDRV KLSQIVDKSI IIHEKPDNFG NVPNPSEKTL
210
MTGDAGARVA CGVISLEQ
Length:218
Mass (Da):22,141
Last modified:December 15, 2009 - v1
Checksum:i860FF7E7D213070C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001802 Genomic DNA. Translation: ACY19989.1.
RefSeqiWP_012832576.1. NC_013441.1.
YP_003271882.1. NC_013441.1.

Genome annotation databases

EnsemblBacteriaiACY19989; ACY19989; Gbro_0664.
KEGGigbr:Gbro_0664.
PATRICi32180811. VBIGorBro114338_0686.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001802 Genomic DNA. Translation: ACY19989.1.
RefSeqiWP_012832576.1. NC_013441.1.
YP_003271882.1. NC_013441.1.

3D structure databases

ProteinModelPortaliD0L2A2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi526226.Gbro_0664.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACY19989; ACY19989; Gbro_0664.
KEGGigbr:Gbro_0664.
PATRICi32180811. VBIGorBro114338_0686.

Phylogenomic databases

eggNOGiCOG2032.
HOGENOMiHOG000263448.
KOiK04565.
OMAiYNQTNGT.
OrthoDBiEOG6K13RS.

Enzyme and pathway databases

BioCyciGBRO526226:GHJF-675-MONOMER.

Family and domain databases

Gene3Di2.60.40.200. 1 hit.
InterProiIPR018152. SOD_Cu/Zn_BS.
IPR001424. SOD_Cu_Zn_dom.
[Graphical view]
PfamiPF00080. Sod_Cu. 1 hit.
[Graphical view]
SUPFAMiSSF49329. SSF49329. 1 hit.
PROSITEiPS00332. SOD_CU_ZN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 25592 / DSM 43247 / JCM 3198 / NCTC 10667Imported.

Entry informationi

Entry nameiD0L2A2_GORB4
AccessioniPrimary (citable) accession number: D0L2A2
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: June 24, 2015
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.