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D0KZW9

- D0KZW9_HALNC

UniProt

D0KZW9 - D0KZW9_HALNC

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Protein
Submitted name:

FolC bifunctional protein

Gene
Hneap_1156
Organism
Halothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus)
Status
Unreviewed - Annotation score: 1 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. dihydrofolate synthase activity Source: UniProtKB-EC
  3. tetrahydrofolylpolyglutamate synthase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHNEA555778:GIVV-1196-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
FolC bifunctional proteinImported (EC:6.3.2.12Imported)
Gene namesi
Ordered Locus Names:Hneap_1156Imported
OrganismiHalothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus)Imported
Taxonomic identifieri555778 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesHalothiobacillaceaeHalothiobacillus
ProteomesiUP000009102: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi555778.Hneap_1156.

Family & Domainsi

Sequence similaritiesi

Belongs to the folylpolyglutamate synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0285.
HOGENOMiHOG000019982.
KOiK11754.
OMAiHRDVASA.
OrthoDBiEOG6ZPSW2.

Family and domain databases

Gene3Di3.40.1190.10. 1 hit.
3.90.190.20. 1 hit.
InterProiIPR001645. Folylpolyglutamate_synth.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
[Graphical view]
PANTHERiPTHR11136. PTHR11136. 1 hit.
PfamiPF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
PIRSFiPIRSF001563. Folylpolyglu_synth. 1 hit.
SUPFAMiSSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
TIGRFAMsiTIGR01499. folC. 1 hit.

Sequencei

Sequence statusi: Complete.

D0KZW9-1 [UniParc]FASTAAdd to Basket

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MSHAPAEQAA LAEWLLWLEA RNPARIDLGL DRVADVWRKL KQEGNLVVPK    50
VITVAGTNGK GSSVALLEAI LLAEGYRVGA YTSPHIERFN ERIRLMGADI 100
QDHELVVAMC QLAATDGSEA LTYYEWATLA AFLAFCRANL DIWILEVGLG 150
GRLDAVNILD ADLALITNIG LDHQAYLGDT RTQIGYEKAG VLRKGQAAVY 200
ADTDPIESVI DHANAIGCPL IVRGRDFMVE ADATGWRLEQ GDRSSYWPLP 250
GMFGRTQVDN AASVVALLQH PKSTLNLRAS SIEAGVRSAK NRGRFEIWVH 300
EGRQVILDVA HNLESVRVLL DNLHALATPS RRLAVFGALD DKPIEAMISL 350
CRPEFDEWYL GQLDSVRSAS IARLSSALDR PQISETSITS AYNAAFAHSA 400
VGDQIIAFGS FYTVSAIRHV LSQSGAHLV 429
Length:429
Mass (Da):46,801
Last modified:December 15, 2009 - v1
Checksum:i1DC1AE3123753081
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001801 Genomic DNA. Translation: ACX95992.1.
RefSeqiWP_012824028.1. NC_013422.1.
YP_003263039.1. NC_013422.1.

Genome annotation databases

EnsemblBacteriaiACX95992; ACX95992; Hneap_1156.
GeneIDi8534308.
KEGGihna:Hneap_1156.
PATRICi32206194. VBIHalNea120669_1168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP001801 Genomic DNA. Translation: ACX95992.1 .
RefSeqi WP_012824028.1. NC_013422.1.
YP_003263039.1. NC_013422.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 555778.Hneap_1156.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACX95992 ; ACX95992 ; Hneap_1156 .
GeneIDi 8534308.
KEGGi hna:Hneap_1156.
PATRICi 32206194. VBIHalNea120669_1168.

Phylogenomic databases

eggNOGi COG0285.
HOGENOMi HOG000019982.
KOi K11754.
OMAi HRDVASA.
OrthoDBi EOG6ZPSW2.

Enzyme and pathway databases

BioCyci HNEA555778:GIVV-1196-MONOMER.

Family and domain databases

Gene3Di 3.40.1190.10. 1 hit.
3.90.190.20. 1 hit.
InterProi IPR001645. Folylpolyglutamate_synth.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
[Graphical view ]
PANTHERi PTHR11136. PTHR11136. 1 hit.
Pfami PF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view ]
PIRSFi PIRSF001563. Folylpolyglu_synth. 1 hit.
SUPFAMi SSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
TIGRFAMsi TIGR01499. folC. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23641 / c2.

Entry informationi

Entry nameiD0KZW9_HALNC
AccessioniPrimary (citable) accession number: D0KZW9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: September 3, 2014
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome

External Data

Dasty 3