Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

FolC bifunctional protein

Gene

Hneap_1156

Organism
Halothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. dihydrofolate synthase activity Source: UniProtKB-EC
  3. tetrahydrofolylpolyglutamate synthase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationImported

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciHNEA555778:GIVV-1196-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
FolC bifunctional proteinImported (EC:6.3.2.12Imported)
Gene namesi
Ordered Locus Names:Hneap_1156Imported
OrganismiHalothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus)Imported
Taxonomic identifieri555778 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesHalothiobacillaceaeHalothiobacillus
ProteomesiUP000009102: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi555778.Hneap_1156.

Family & Domainsi

Sequence similaritiesi

Belongs to the folylpolyglutamate synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0285.
HOGENOMiHOG000019982.
KOiK11754.
OMAiFWLFERA.
OrthoDBiEOG6ZPSW2.

Family and domain databases

Gene3Di3.40.1190.10. 1 hit.
3.90.190.20. 1 hit.
InterProiIPR001645. Folylpolyglutamate_synth.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
[Graphical view]
PANTHERiPTHR11136. PTHR11136. 1 hit.
PfamiPF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
PIRSFiPIRSF001563. Folylpolyglu_synth. 1 hit.
SUPFAMiSSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
TIGRFAMsiTIGR01499. folC. 1 hit.

Sequencei

Sequence statusi: Complete.

D0KZW9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSHAPAEQAA LAEWLLWLEA RNPARIDLGL DRVADVWRKL KQEGNLVVPK
60 70 80 90 100
VITVAGTNGK GSSVALLEAI LLAEGYRVGA YTSPHIERFN ERIRLMGADI
110 120 130 140 150
QDHELVVAMC QLAATDGSEA LTYYEWATLA AFLAFCRANL DIWILEVGLG
160 170 180 190 200
GRLDAVNILD ADLALITNIG LDHQAYLGDT RTQIGYEKAG VLRKGQAAVY
210 220 230 240 250
ADTDPIESVI DHANAIGCPL IVRGRDFMVE ADATGWRLEQ GDRSSYWPLP
260 270 280 290 300
GMFGRTQVDN AASVVALLQH PKSTLNLRAS SIEAGVRSAK NRGRFEIWVH
310 320 330 340 350
EGRQVILDVA HNLESVRVLL DNLHALATPS RRLAVFGALD DKPIEAMISL
360 370 380 390 400
CRPEFDEWYL GQLDSVRSAS IARLSSALDR PQISETSITS AYNAAFAHSA
410 420
VGDQIIAFGS FYTVSAIRHV LSQSGAHLV
Length:429
Mass (Da):46,801
Last modified:December 15, 2009 - v1
Checksum:i1DC1AE3123753081
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001801 Genomic DNA. Translation: ACX95992.1.
RefSeqiWP_012824028.1. NC_013422.1.
YP_003263039.1. NC_013422.1.

Genome annotation databases

EnsemblBacteriaiACX95992; ACX95992; Hneap_1156.
GeneIDi8534308.
KEGGihna:Hneap_1156.
PATRICi32206194. VBIHalNea120669_1168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001801 Genomic DNA. Translation: ACX95992.1.
RefSeqiWP_012824028.1. NC_013422.1.
YP_003263039.1. NC_013422.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi555778.Hneap_1156.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACX95992; ACX95992; Hneap_1156.
GeneIDi8534308.
KEGGihna:Hneap_1156.
PATRICi32206194. VBIHalNea120669_1168.

Phylogenomic databases

eggNOGiCOG0285.
HOGENOMiHOG000019982.
KOiK11754.
OMAiFWLFERA.
OrthoDBiEOG6ZPSW2.

Enzyme and pathway databases

BioCyciHNEA555778:GIVV-1196-MONOMER.

Family and domain databases

Gene3Di3.40.1190.10. 1 hit.
3.90.190.20. 1 hit.
InterProiIPR001645. Folylpolyglutamate_synth.
IPR004101. Mur_ligase_C.
IPR013221. Mur_ligase_cen.
[Graphical view]
PANTHERiPTHR11136. PTHR11136. 1 hit.
PfamiPF02875. Mur_ligase_C. 1 hit.
PF08245. Mur_ligase_M. 1 hit.
[Graphical view]
PIRSFiPIRSF001563. Folylpolyglu_synth. 1 hit.
SUPFAMiSSF53244. SSF53244. 1 hit.
SSF53623. SSF53623. 1 hit.
TIGRFAMsiTIGR01499. folC. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23641 / c2Imported.

Entry informationi

Entry nameiD0KZW9_HALNC
AccessioniPrimary (citable) accession number: D0KZW9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: February 4, 2015
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.