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D0KZH2 (D0KZH2_HALNC) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 23. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Ribonucleoside-diphosphate reductase subunit beta PIRNR PIRNR000355
EC=1.17.4.1 PIRNR PIRNR000355
Gene names
Ordered Locus Names:Hneap_1009
OrganismHalothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus) [Complete proteome] [HAMAP]
Taxonomic identifier555778 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Chromatiales › Halothiobacillaceae › Halothiobacillus ›

Protein attributes

Sequence length398 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides By similarity. PIRNR PIRNR000355

Catalytic activity

2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. PIRNR PIRNR000355

Cofactor

Binds 2 iron ions per subunit By similarity. PIRNR PIRNR000355

Pathway

Genetic information processing; DNA replication. PIRNR PIRNR000355

Sequence similarities

Belongs to the ribonucleoside diphosphate reductase small chain family. PIRNR PIRNR000355

Sequences

Sequence LengthMass (Da)Tools
D0KZH2 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: 92B37C0F244D2306

FASTA39845,034
        10         20         30         40         50         60 
MLNWNELEAK SNPNAGMTPE MMSNMTSAMD DTTDVTQAVD SGDHASPHGQ TGLEGIAQGA 

        70         80         90        100        110        120 
GRVDVSAKRI INATADVNQL LPMKYTWAWE KYLAGCNNHW MPTEVSMQAD IALWKGRDGG 

       130        140        150        160        170        180 
LTADERAMIM RNLGFFATAE SLVANNIVLA IYKQVTNPEC RQYLLRQAFE EAVHTHTFQY 

       190        200        210        220        230        240 
IVESLGLAEG ELFNMYREIP SITAKDEWAL KYTKNLADGD FDTSTTKGAQ DFLRDLVAFY 

       250        260        270        280        290        300 
VVFEGMWFYT GFAQILSLGR RNKMTGIAEQ YQYIMRDESI HMNFGIDVIN QIKIENPHLW 

       310        320        330        340        350        360 
TEDFKAEVTR MLKEAAELEI AYARDTMPHG LLGLNAEMCA EYLHFIANRR CNQIGLAELF 

       370        380        390 
PGATNPFPWM SEVIDLKKEK NFFETRVTDY QTGGALNW

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References

[1]"Complete sequence of Halothiobacillus neapolitanus c2."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Davenport K., Brettin T., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Mikhailova N. expand/collapse author list , Kerfeld C., Cannon G., Heinhort S.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 23641 / c2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001801 Genomic DNA. Translation: ACX95845.1.
RefSeqYP_003262892.1. NC_013422.1.

3D structure databases

ProteinModelPortalD0KZH2.
ModBaseSearch...

Protein-protein interaction databases

STRING555778.Hneap_1009.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACX95845; ACX95845; Hneap_1009.
GeneID8534156.
KEGGhna:Hneap_1009.
PATRIC32205878. VBIHalNea120669_1015.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0208.
HOGENOMHOG000255976.
KOK00526.
OMAICNRRCQ.

Enzyme and pathway databases

BioCycHNEA555778:GIVV-1044-MONOMER.
UniPathwayUPA00326.

Family and domain databases

Gene3D1.10.620.20. 1 hit.
InterProIPR009078. Ferritin-like_SF.
IPR012348. RNR-rel.
IPR026023. RNR_bsu_prok.
IPR000358. RNR_small.
[Graphical view]
PANTHERPTHR23409. PTHR23409. 1 hit.
PfamPF00268. Ribonuc_red_sm. 1 hit.
[Graphical view]
PIRSFPIRSF000355. NrdB. 1 hit.
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD0KZH2_HALNC
AccessionPrimary (citable) accession number: D0KZH2
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: May 1, 2013
This is version 23 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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