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D0KZG1

- D0KZG1_HALNC

UniProt

D0KZG1 - D0KZG1_HALNC

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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Halothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Note: Magnesium.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei147 – 1471UniRule annotation
Active sitei595 – 5951UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciHNEA555778:GIVV-1033-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:Hneap_0998Imported
OrganismiHalothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus)Imported
Taxonomic identifieri555778 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesHalothiobacillaceaeHalothiobacillus
ProteomesiUP000009102: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi555778.Hneap_0998.

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG2352.
HOGENOMiHOG000238647.
KOiK01595.
OMAiISCQHYR.
OrthoDBiEOG6TJ7T8.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0KZG1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKKNSKDNDK ALRARVRLFG NLLGEVLKEQ TGDHVFDTVE TLRRGFIKLR
60 70 80 90 100
LKHNPKLHAK LMVLLRTLDP DTLNFVVRAY NLYFSLVNIA EEDFMHQHRR
110 120 130 140 150
KQVRLGLRLW RGSFYDTMRE FSKQGMSPDD LQTLLNRLIY MPVFTAHPTE
160 170 180 190 200
AKRRTVMDLQ RKIFLLCAEL DHPEAKGIER DRLHQQVKSV ILSLLKTNEV
210 220 230 240 250
RTTRPEVHDE IRLGLYYFST SIFDAVPLAY RYLERAVDVN FNEKFPDAPV
260 270 280 290 300
TVPSLFRFGS WIGGDRDGNP YVTHEVTTFA VCSATQTILQ EYLDRLAGMD
310 320 330 340 350
RVLTHSCRLC PEIDLEGLGL HQDAVELGLA SPENSGDSFF TEEPYRLKLR
360 370 380 390 400
IIGQRLKHNL DYVTALLDKK PINLSAHAYA HKDQFLSDLY RIRDTLISTG
410 420 430 440 450
DQLLADGEIK DLIRLAETFG WHLFKLDIRQ ESTRHTQTVA DILKQLQPKT
460 470 480 490 500
DYMALDEAGR MTLLTQLINK SRHKAIDMAA LSAESAETLE VFKVKRELID
510 520 530 540 550
TISRECFGTY VISMTHAASH VMEVMFLAVL AGLAGKRKSQ WFCDIQISPL
560 570 580 590 600
FETIEDLHQI ENVLSVLFEN PVYRELIRVS GDLQEAMLGY SDSCKDGGSL
610 620 630 640 650
ASVWSLYNAQ KRVLSITQKN GIECRLFHGR GGTVARGGGP THESILSLPA
660 670 680 690 700
GTVEGQIKFT EQGEVLSSKY SNTETAIYEI TMGATGLMKA SAHLVMENNP
710 720 730 740 750
APAEHEQVVA ELATYGEKAY RELTDETPFF FNYFFEATPV RELGLLNIGS
760 770 780 790 800
RPASRKVGDL SKASVRAIPW VFGWSQSRHT LPAWYGIGSA LRAWRQSHKD
810 820 830 840 850
QPELLHTLFN EWPFFHSMLR NTQLSLTKGE MTIAREYASL VADQAQALPV
860 870 880 890 900
YDKISTEYYR TLDELLRVAR VDSLVEIDEY IGTSMMRRNP YLDVLNHIQI
910 920 930
VLLRRYRDDS EPEAERQKWL LPLLRSINAI ASGMRNTG
Length:938
Mass (Da):106,985
Last modified:December 15, 2009 - v1
Checksum:i7103A2F2471FFF93
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001801 Genomic DNA. Translation: ACX95834.1.
RefSeqiYP_003262881.1. NC_013422.1.

Genome annotation databases

EnsemblBacteriaiACX95834; ACX95834; Hneap_0998.
GeneIDi8534145.
KEGGihna:Hneap_0998.
PATRICi32205858. VBIHalNea120669_1005.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001801 Genomic DNA. Translation: ACX95834.1 .
RefSeqi YP_003262881.1. NC_013422.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 555778.Hneap_0998.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACX95834 ; ACX95834 ; Hneap_0998 .
GeneIDi 8534145.
KEGGi hna:Hneap_0998.
PATRICi 32205858. VBIHalNea120669_1005.

Phylogenomic databases

eggNOGi COG2352.
HOGENOMi HOG000238647.
KOi K01595.
OMAi ISCQHYR.
OrthoDBi EOG6TJ7T8.

Enzyme and pathway databases

BioCyci HNEA555778:GIVV-1033-MONOMER.

Family and domain databases

HAMAPi MF_00595. PEPcase_type1.
InterProi IPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view ]
Pfami PF00311. PEPcase. 1 hit.
[Graphical view ]
PRINTSi PR00150. PEPCARBXLASE.
SUPFAMi SSF51621. SSF51621. 1 hit.
PROSITEi PS00781. PEPCASE_1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23641 / c2Imported.

Entry informationi

Entry nameiD0KZG1_HALNC
AccessioniPrimary (citable) accession number: D0KZG1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: November 26, 2014
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3