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D0KXH0

- D0KXH0_HALNC

UniProt

D0KXH0 - D0KXH0_HALNC

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Protein
Elongation factor Tu
Gene
tuf, Hneap_0321
Organism
Halothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi19 – 268GTP By similarityUniRule annotation
Nucleotide bindingi81 – 855GTP By similarityUniRule annotation
Nucleotide bindingi136 – 1394GTP By similarityUniRule annotation

GO - Molecular functioni

  1. GTP binding Source: UniProtKB-HAMAP
  2. GTPase activity Source: InterPro
  3. translation elongation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Keywords - Molecular functioni

    Elongation factorUniRule annotationImported

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    GTP-bindingUniRule annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciHNEA555778:GIVV-328-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Elongation factor TuUniRule annotation
    Short name:
    EF-TuUniRule annotation
    Gene namesi
    Name:tufUniRule annotation
    Ordered Locus Names:Hneap_0321Imported
    OrganismiHalothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus)Imported
    Taxonomic identifieri555778 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesHalothiobacillaceaeHalothiobacillus
    ProteomesiUP000009102: Chromosome

    Subcellular locationi

    Cytoplasm By similarity UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    Complete GO annotation...

    Keywords - Cellular componenti

    CytoplasmUniRule annotation

    Interactioni

    Subunit structurei

    Monomer By similarity.UniRule annotation

    Protein-protein interaction databases

    STRINGi555778.Hneap_0321.

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    HOGENOMiHOG000229290.
    KOiK02358.
    OMAiMIVELIM.
    OrthoDBiEOG6R5C6X.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    HAMAPiMF_00118_B. EF_Tu_B.
    InterProiIPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view]
    PfamiPF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view]
    PRINTSiPR00315. ELONGATNFCT.
    SUPFAMiSSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEiPS00301. EFACTOR_GTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D0KXH0-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSKEKFERNK PHVNVGTIGH VDHGKTTLTA AITKVMAEMH GGASLGYDQI    50
    DKAPEEKARG ITINTSHVEY ESDTRHYAHV DCPGHADYVK NMITGAAQMD 100
    GAILVCSAAD GPMPQTREHI LLSRQVGVPY IVVFLNKADM VDDPELLELV 150
    EMEIRDLLSK YEFPGDDTPI VTGSALKALE GDTSDIGVPS VIKLVKAMDD 200
    YFPEPERAVD GTFLMPVEDV FSISGRGTVV TGRIERGIVK VGEEVEIVGI 250
    RDTTKTTVTG VEMFRKLLDQ GMAGDNVGIL LRGTKRDDVE RGQVLCKPGS 300
    IKPHTKFEAE VYILGKDEGG RHTPFFNGYR PQFYFRTTDV TGSCVLPEGT 350
    EMVMPGDNVA MTVSLIAPIA MEDGLRFAIR EGGRTVGAGV VSKIIE 396
    Length:396
    Mass (Da):43,097
    Last modified:December 15, 2009 - v1
    Checksum:i4406DAFAC34336B8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001801 Genomic DNA. Translation: ACX95184.1.
    RefSeqiYP_003262231.1. NC_013422.1.

    Genome annotation databases

    EnsemblBacteriaiACX95184; ACX95184; Hneap_0321.
    GeneIDi8533441.
    KEGGihna:Hneap_0321.
    PATRICi32204442. VBIHalNea120669_0322.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001801 Genomic DNA. Translation: ACX95184.1 .
    RefSeqi YP_003262231.1. NC_013422.1.

    3D structure databases

    ModBasei Search...

    Protein-protein interaction databases

    STRINGi 555778.Hneap_0321.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACX95184 ; ACX95184 ; Hneap_0321 .
    GeneIDi 8533441.
    KEGGi hna:Hneap_0321.
    PATRICi 32204442. VBIHalNea120669_0322.

    Phylogenomic databases

    HOGENOMi HOG000229290.
    KOi K02358.
    OMAi MIVELIM.
    OrthoDBi EOG6R5C6X.

    Enzyme and pathway databases

    BioCyci HNEA555778:GIVV-328-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    HAMAPi MF_00118_B. EF_Tu_B.
    InterProi IPR000795. EF_GTP-bd_dom.
    IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR009000. Transl_B-barrel.
    IPR009001. Transl_elong_EF1A/Init_IF2_C.
    IPR004161. Transl_elong_EFTu/EF1A_2.
    IPR004541. Transl_elong_EFTu/EF1A_bac/org.
    IPR004160. Transl_elong_EFTu/EF1A_C.
    [Graphical view ]
    Pfami PF00009. GTP_EFTU. 1 hit.
    PF03144. GTP_EFTU_D2. 1 hit.
    PF03143. GTP_EFTU_D3. 1 hit.
    [Graphical view ]
    PRINTSi PR00315. ELONGATNFCT.
    SUPFAMi SSF50447. SSF50447. 1 hit.
    SSF50465. SSF50465. 1 hit.
    SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00485. EF-Tu. 1 hit.
    TIGR00231. small_GTP. 1 hit.
    PROSITEi PS00301. EFACTOR_GTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 23641 / c2.

    Entry informationi

    Entry nameiD0KXH0_HALNC
    AccessioniPrimary (citable) accession number: D0KXH0
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2009
    Last sequence update: December 15, 2009
    Last modified: June 11, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    External Data

    Dasty 3

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