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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

Hneap_2371

Organism
Halothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: InterPro
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciHNEA555778:GIVV-2423-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported
Gene namesi
Ordered Locus Names:Hneap_2371Imported
OrganismiHalothiobacillus neapolitanus (strain ATCC 23641 / c2) (Thiobacillus neapolitanus)Imported
Taxonomic identifieri555778 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaChromatialesHalothiobacillaceaeHalothiobacillus
ProteomesiUP000009102: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi555778.Hneap_2371.

Structurei

3D structure databases

ProteinModelPortaliD0KX60.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK00823.
OMAiGQRLTNT.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0KX60-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTAHAMTKSA QTTAPNDQSM NADLQARRLA ATPRGVGVMA GFYIDRAQNA
60 70 80 90 100
EVWDVEGNRY IDFAGGIAVL NTGHRHPALV AAIEEQLKRF THTCYQVLPY
110 120 130 140 150
ESYVRLAERI NALVPGHYAK KTAFFSSGAE AVENAVKIAR SSTGRPGIIA
160 170 180 190 200
FSGGFHGRTM MGCALTGKVV PYKVGFGPFP SEVYHLPFPM ELHGVTVEDS
210 220 230 240 250
LHALETLFKA EIEPSRVAAI IIEPVQGEGG FYVAPPQLLH GLRKVCDEHG
260 270 280 290 300
ILLIFDEVQT GFGRTGKLFA TEYYDVLPDI VTMAKSMAGG MTLSAVCGRA
310 320 330 340 350
EVMDAPAPGG LGGTYAGNPL AIAAALAVID VMEKEQLVER SNFLGEKLMA
360 370 380 390 400
RLNAAQAAVP ALKEVRGLGS MVAAEFCDPA TGAPSPDAVK RVQQAALEEG
410 420 430 440
LILLTCGVYA NVIRFLYPLT TEDTVFDEAL DILDRALAKA
Length:440
Mass (Da):47,057
Last modified:December 15, 2009 - v1
Checksum:i6810A67453CF4384
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001801 Genomic DNA. Translation: ACX97180.1.
RefSeqiYP_003264227.1. NC_013422.1.

Genome annotation databases

EnsemblBacteriaiACX97180; ACX97180; Hneap_2371.
GeneIDi8535535.
KEGGihna:Hneap_2371.
PATRICi32208764. VBIHalNea120669_2441.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001801 Genomic DNA. Translation: ACX97180.1.
RefSeqiYP_003264227.1. NC_013422.1.

3D structure databases

ProteinModelPortaliD0KX60.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi555778.Hneap_2371.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACX97180; ACX97180; Hneap_2371.
GeneIDi8535535.
KEGGihna:Hneap_2371.
PATRICi32208764. VBIHalNea120669_2441.

Phylogenomic databases

eggNOGiCOG0160.
HOGENOMiHOG000020206.
KOiK00823.
OMAiGQRLTNT.
OrthoDBiEOG6QVRHN.

Enzyme and pathway databases

BioCyciHNEA555778:GIVV-2423-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 23641 / c2Imported.

Entry informationi

Entry nameiD0KX60_HALNC
AccessioniPrimary (citable) accession number: D0KX60
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: January 7, 2015
This is version 29 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.