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D0KT41 (D0KT41_SULS9) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 11. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylformylglycinamidine synthase 2 HAMAP MF_00420
EC=6.3.5.3 HAMAP MF_00420
Alternative name(s):
Phosphoribosylformylglycinamidine synthase II HAMAP MF_00420
Gene names
Name:purL HAMAP MF_00420
Ordered Locus Names:Ssol_1693
OrganismSulfolobus solfataricus (strain 98/2) [Complete proteome] [HAMAP]
Taxonomic identifier555311 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length709 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate. HAMAP MF_00420

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2. HAMAP MF_00420

Subunit structure

Heterodimer of two subunits, PurQ and PurL By similarity. HAMAP MF_00420

Subcellular location

Cytoplasm By similarity HAMAP MF_00420.

Sequence similarities

Belongs to the FGAMS family. HAMAP MF_00420

Ontologies

Keywords
   Biological processPurine biosynthesis HAMAP MF_00420
   Cellular componentCytoplasm HAMAP MF_00420
   LigandATP-binding HAMAP MF_00420
Nucleotide-binding
   Molecular functionLigase HAMAP MF_00420
   Technical termComplete proteome
Gene Ontology (GO)
   Biological process'de novo' IMP biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred from electronic annotation. Source: HAMAP

phosphoribosylformylglycinamidine synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
D0KT41 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: 150777DE8D23E5CA

FASTA70977,089
        10         20         30         40         50         60 
MGINLLPIEM DEIRKRLGRE PNETEWRVID AVWSEHCSYK SSKIFLKSFS IDSPNVIMGI 

        70         80         90        100        110        120 
KDWQDAGAVD IGDGWAVVIK VESHNHPSAI DPFNGAATGV GGIIRDIISK GAKPIALMDM 

       130        140        150        160        170        180 
IRVGNLKIKK NVWLLKNIIA GIAAYGNSIG VPVVGGELSF DDTYNDNPLV DVAAIGIVRK 

       190        200        210        220        230        240 
DKIKPSIVDK AGLKLVLAGL TGVDGLGGAS FASRKLSGED EIGAVQIADP FAGKIILDVT 

       250        260        270        280        290        300 
LEIADKVEAI KDLGGGGLAV AVTEITNGLG ATVDIEKIPL RVKNMNPSDV IISETQERML 

       310        320        330        340        350        360 
YAVEEKNVKE VCEAFEEYEY PCSVIGEITN EPVIKFRYIG KDLVSLPTNV LLNPPRFLWP 

       370        380        390        400        410        420 
IKNTKKNVEE KIVDLPLESA IYTVLTHPDL VSKGWAYSQF DYEVNTSTVV KPGDADSAVV 

       430        440        450        460        470        480 
SLPNGKLLAI KADANPDMCA EDGYECGKGI VAEAYRNLAT VGARGMVAVD HLQFGDPKKA 

       490        500        510        520        530        540 
EVYYTFVEAI RGIGEATRFF NIPIVGGKVS FYNENNQGRP IKPTPLIVMA GLVQDKLLKN 

       550        560        570        580        590        600 
RVEDNLYVVS VGYTRKELGG SLLSKIFKIP SQAPKVRLQE DLLSSEVVID SINEGKITFA 

       610        620        630        640        650        660 
KDVSRGGLAA SLFSILVHGY GVEISTKSIL SDTDNVIENL FSESSGRFIV LTNEPEWIVE 

       670        680        690        700 
KSKSKGIVAS IIGRVNKKTN ILTIDNIDYN LKNIVDNYFN FLEEVMGNG

« Hide

References

[1]"Complete sequence of Sulfolobus solfataricus 98/2."
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Mead D.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 98/2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001800 Genomic DNA. Translation: ACX91910.1.

3D structure databases

ProteinModelPortalD0KT41.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GenomeReviewsGene locus Ssol_1693 in contig CP001800_GR.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAYGNSFGV.

Family and domain databases

HAMAPMF_00420. PurL_2.
[Tree]
InterProIPR000728. AIR_synth.
IPR010918. AIR_synth_C.
IPR010074. PRibForGlyAmidine_synth_II.
IPR016188. PurM_N-like.
[Graphical view]
PfamPF00586. AIRS. 2 hits.
PF02769. AIRS_C. 2 hits.
[Graphical view]
SUPFAMSSF56042. AIR_synth_C. 2 hits.
SSF55326. PurM_N-like. 2 hits.
TIGRFAMsTIGR01736. FGAM_synth_II. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD0KT41_SULS9
AccessionPrimary (citable) accession number: D0KT41
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: January 25, 2012
This is version 11 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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