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D0KRN9 (D0KRN9_SULS9) Unreviewed, UniProtKB/TrEMBL

Last modified May 1, 2013. Version 27. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DNA ligase HAMAP-Rule MF_00407 RuleBase RU000617
EC=6.5.1.1 HAMAP-Rule MF_00407 RuleBase RU000617
Alternative name(s):
Polydeoxyribonucleotide synthase [ATP] HAMAP-Rule MF_00407
Gene names
Name:lig HAMAP-Rule MF_00407
Ordered Locus Names:Ssol_1170
OrganismSulfolobus solfataricus (strain 98/2) [Complete proteome] [HAMAP]
Taxonomic identifier555311 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus ›

Protein attributes

Sequence length601 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair By similarity. HAMAP-Rule MF_00407

Catalytic activity

ATP + (deoxyribonucleotide)(n) + (deoxyribonucleotide)(m) = AMP + diphosphate + (deoxyribonucleotide)(n+m). HAMAP-Rule MF_00407 RuleBase RU000617

Cofactor

Divalent metal cations By similarity. HAMAP-Rule MF_00407

Sequence similarities

Belongs to the ATP-dependent DNA ligase family. HAMAP-Rule MF_00407 RuleBase RU004196

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site2601N6-AMP-lysine intermediate By similarity HAMAP-Rule MF_00407
Binding site2581ATP By similarity HAMAP-Rule MF_00407
Binding site2651ATP By similarity HAMAP-Rule MF_00407
Binding site2801ATP By similarity HAMAP-Rule MF_00407
Binding site3101ATP By similarity HAMAP-Rule MF_00407
Binding site3501ATP By similarity HAMAP-Rule MF_00407
Binding site4271ATP By similarity HAMAP-Rule MF_00407
Binding site4331ATP By similarity HAMAP-Rule MF_00407

Sequences

Sequence LengthMass (Da)Tools
D0KRN9 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: DA6814F4A6F0546E

FASTA60167,733
        10         20         30         40         50         60 
MEFKVIAEYF DKLEKISSRL QLTALLADLL SKSDKTIIDK VVYIIQGKLW PDFLGYPELG 

        70         80         90        100        110        120 
IGEKFLIKAI SIATNTDENS VENLYKTIGD LGEVARRLKS KQQSTGILGF LGTTSKESLT 

       130        140        150        160        170        180 
VDEVYSTLSK VALTTGEGSR DLKIRLLAGL LKKADPLEAK FLVRFVEGRL RVGIGDATVL 

       190        200        210        220        230        240 
DAMAIAFGGG QSASEIIERA YNLRADLGNI AKIIVEKGIE ALKTLKPQVG IPIRPMLAER 

       250        260        270        280        290        300 
LSNPEEILKK MGGNAIVDYK YDGERAQIHK KEDKIFIFSR RLENITSQYP DVVDYVSKYI 

       310        320        330        340        350        360 
EGKEFIIEGE IVAIDPESGE MRPFQELMHR KRKSDIYEAI KEYPVNVFLF DLMYYEDVDY 

       370        380        390        400        410        420 
TTKPLEARRK LLESIVKPND YVKIAHHIQA NNVEDLKSFF YRAISEGGEG VMVKAIGKDA 

       430        440        450        460        470        480 
IYQAGARGWL WIKLKRDYQS EMADTVDLVV VGGFYGKGKR GGKISSLLMA AYNPKTDSFE 

       490        500        510        520        530        540 
SVCKVASGFS DEQLDELQKK LMEIKRDVKH PRVNSKMEPD IWVEPVYVAE IIGSEITISP 

       550        560        570        580        590        600 
LHTCCQDVVE KDAGLSIRFP RFIRWRDDKS PEDATTTDEI LEMYNKQPKK KIESPAVDES 


V

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References

[1]"Complete sequence of Sulfolobus solfataricus 98/2."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Mead D.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 98/2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001800 Genomic DNA. Translation: ACX91408.1.
RefSeqYP_005643009.1. NC_017274.1.

3D structure databases

ProteinModelPortalD0KRN9.
SMRD0KRN9. Positions 1-590.
ModBaseSearch...

Proteomic databases

PRIDED0KRN9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACX91408; ACX91408; Ssol_1170.
GeneID12258559.
KEGGsol:Ssol_1170.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000036008.
KOK10747.
OMAAQVACLY.

Family and domain databases

Gene3D1.10.3260.10. 1 hit.
2.40.50.140. 1 hit.
HAMAPMF_00407. DNA_ligase.
InterProIPR022865. DNA_ligae_ATP-dep_bac/arc.
IPR000977. DNA_ligase_ATP-dep.
IPR012309. DNA_ligase_ATP-dep_C.
IPR012310. DNA_ligase_ATP-dep_cent.
IPR016059. DNA_ligase_ATP-dep_CS.
IPR012308. DNA_ligase_ATP-dep_N.
IPR012340. NA-bd_OB-fold.
[Graphical view]
PfamPF04679. DNA_ligase_A_C. 1 hit.
PF01068. DNA_ligase_A_M. 1 hit.
PF04675. DNA_ligase_A_N. 1 hit.
[Graphical view]
SUPFAMSSF50249. Nucleic_acid_OB. 1 hit.
SSF117018. SSF117018. 1 hit.
TIGRFAMsTIGR00574. dnl1. 1 hit.
PROSITEPS00697. DNA_LIGASE_A1. 1 hit.
PS00333. DNA_LIGASE_A2. 1 hit.
PS50160. DNA_LIGASE_A3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0KRN9_SULS9
AccessionPrimary (citable) accession number: D0KRN9
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: May 1, 2013
This is version 27 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info