D0KQJ8 (D0KQJ8_SULS9) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
NH(3)-dependent NAD(+) synthetase HAMAP MF_00193 RuleBase RU003812
EC=6.3.1.5 HAMAP MF_00193 RuleBase RU003812

Gene names

Name:	nadE HAMAP MF_00193
Ordered Locus Names:	Ssol_2901

Organism

Sulfolobus solfataricus (strain 98/2) [Complete proteome] [HAMAP]

Taxonomic identifier

555311 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	304 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+. HAMAP MF_00193 RuleBase RU003812
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1. RuleBase RU004252 HAMAP MF_00193
Sequence similarities	Belongs to the NAD synthetase family. HAMAP MF_00193 RuleBase RU003811

Ontologies

Keywords
Ligand	ATP-binding HAMAP MF_00193 RuleBase RU003811 NAD HAMAP MF_00193 RuleBase RU003811 Nucleotide-binding
Molecular function	Ligase HAMAP MF_00193 RuleBase RU003811 EMBL ACX92975.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP NAD+ synthase (glutamine-hydrolyzing) activity Inferred from electronic annotation. Source: InterPro NAD+ synthase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Regions
	Nucleotide binding	65 – 72	8	ATP By similarity HAMAP MF_00193
Sites
	Active site	67	1	By similarity HAMAP MF_00193

Sequences

	Sequence		Length	Mass (Da)
	D0KQJ8 [UniParc]. Last modified December 15, 2009. Version 1. Checksum: 31CBF400D1F00CEA	FASTA	304	34,711
	10 20 30 40 50 60 MAFSKFSSFR WYYTLNICST NILIMVMHEY IRKSLTIDCE AVTNYIVERI REYLEFSNKK 70 80 90 100 110 120 GGVIGVSGGV DSAVTATLLA KATDNFFILL MPSSSTPKID LDDSFEMIKF LNAQNKYKLI 130 140 150 160 170 180 NIDEIVKSFS NKIETENKYI IGNIKARVRM IILYAYAQML DYLVVGTGDK SELLLGYFTK 190 200 210 220 230 240 YGDGGVDVLP IGDLYKTQVR MLGKCLGLPE RIVTKPSSPA LWEGQTAEGE LGIDYETIDS 250 260 270 280 290 300 ILYLRFDEMR SEDEIVKMLG IPIDIVKKVD RLVKISQHKR LPPEIFRLSG RAINSDWRFP RRWA

References

[1]

"Complete sequence of Sulfolobus solfataricus 98/2." Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Munk A.C., Brettin T., Detter J.C., Han C., Tapia R., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Mead D. Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 98/2.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001800 Genomic DNA. Translation: ACX92975.1.
3D structure databases
ProteinModelPortal	D0KQJ8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GenomeReviews	Gene locus Ssol_2901 in contig CP001800_GR.
Organism-specific databases
CMR	Search...
Phylogenomic databases
OMA	DGAVDCH.
Family and domain databases
HAMAP	MF_00193. NadE. [Tree]
InterPro	IPR022310. NAD/GMP_synthase. IPR003694. NAD_synthase. IPR022926. NH(3)-dep_NAD(+)_synth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
Pfam	PF02540. NAD_synthase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00552. NadE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

D0KQJ8_SULS9

Accession

Primary (citable) accession number: D0KQJ8

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2009
Last sequence update:	December 15, 2009
Last modified:	December 14, 2011
This is version 16 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)