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D0KLP4

- D0KLP4_PECWW

UniProt

D0KLP4 - D0KLP4_PECWW

Protein

Alanine racemase

Gene

Pecwa_3637

Organism
Pectobacterium wasabiae (strain WPP163)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 41 (01 Oct 2014)
      Sequence version 1 (15 Dec 2009)
      Previous versions | rss
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    Functioni

    Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.UniRule annotation

    Catalytic activityi

    L-alanine = D-alanine.UniRule annotationSAAS annotation

    Cofactori

    Pyridoxal phosphate.UniRule annotationSAAS annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei34 – 341Proton acceptor; specific for D-alanineUniRule annotation
    Binding sitei129 – 1291SubstrateUniRule annotation
    Active sitei254 – 2541Proton acceptor; specific for L-alanineUniRule annotation
    Binding sitei302 – 3021Substrate; via amide nitrogenUniRule annotation

    GO - Molecular functioni

    1. alanine racemase activity Source: UniProtKB-HAMAP
    2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

    GO - Biological processi

    1. D-alanine biosynthetic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    IsomeraseUniRule annotationSAAS annotationImported

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotationSAAS annotation

    Enzyme and pathway databases

    BioCyciPWAS561231:GHO0-3714-MONOMER.
    UniPathwayiUPA00042; UER00497.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
    Gene namesi
    Ordered Locus Names:Pecwa_3637Imported
    OrganismiPectobacterium wasabiae (strain WPP163)Imported
    Taxonomic identifieri561231 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium
    ProteomesiUP000000315: Chromosome

    PTM / Processingi

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei34 – 341N6-(pyridoxal phosphate)lysineUniRule annotation

    Proteomic databases

    PRIDEiD0KLP4.

    Interactioni

    Protein-protein interaction databases

    STRINGi561231.Pecwa_3637.

    Structurei

    3D structure databases

    ProteinModelPortaliD0KLP4.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the alanine racemase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0787.
    HOGENOMiHOG000031446.
    KOiK01775.
    OMAiLWQLEAI.
    OrthoDBiEOG6PP9NJ.

    Family and domain databases

    Gene3Di2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPiMF_01201. Ala_racemase.
    InterProiIPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view]
    PfamiPF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view]
    PRINTSiPR00992. ALARACEMASE.
    SMARTiSM01005. Ala_racemase_C. 1 hit.
    [Graphical view]
    SUPFAMiSSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsiTIGR00492. alr. 1 hit.
    PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    D0KLP4-1 [UniParc]FASTAAdd to Basket

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    MKTATAVISR RALRHNLQRI RQLAPGSQVV AVVKANAYGH GMIESAHTFC    50
    DADCYGVARL SEALALRAAG ITKPIVLLEG FFSADDLPLL AEHQLETAVH 100
    SPEQLAALEQ ATLPQPLRVW MKLDTGMHRL GVLPEQADAF WQRLTECRNV 150
    VQPVNIMSHF CRADEPEAGT TERQLACFDA FTQGKPGAQS IAASGGILLW 200
    PQAHRDRVRP GIILYGVSPL DNEDAAHFGF QPAMTFTSHL IAVREHKAGE 250
    AVGYGSTWTS PRDTRLGVVA VGYGDGYPRC APAGTPVLIN GREVPLSGRV 300
    SMDMITIDLG PDAQDKVGDE AILWGPALSV ERIAAHTGVS AYELITRLTQ 350
    RATLEYTDN 359
    Length:359
    Mass (Da):38,876
    Last modified:December 15, 2009 - v1
    Checksum:iD13BCE5F15169B84
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001790 Genomic DNA. Translation: ACX89373.1.
    RefSeqiYP_003260980.1. NC_013421.1.

    Genome annotation databases

    EnsemblBacteriaiACX89373; ACX89373; Pecwa_3637.
    GeneIDi8532063.
    KEGGipwa:Pecwa_3637.
    PATRICi32281562. VBIPecWas23660_3576.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001790 Genomic DNA. Translation: ACX89373.1 .
    RefSeqi YP_003260980.1. NC_013421.1.

    3D structure databases

    ProteinModelPortali D0KLP4.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 561231.Pecwa_3637.

    Proteomic databases

    PRIDEi D0KLP4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACX89373 ; ACX89373 ; Pecwa_3637 .
    GeneIDi 8532063.
    KEGGi pwa:Pecwa_3637.
    PATRICi 32281562. VBIPecWas23660_3576.

    Phylogenomic databases

    eggNOGi COG0787.
    HOGENOMi HOG000031446.
    KOi K01775.
    OMAi LWQLEAI.
    OrthoDBi EOG6PP9NJ.

    Enzyme and pathway databases

    UniPathwayi UPA00042 ; UER00497 .
    BioCyci PWAS561231:GHO0-3714-MONOMER.

    Family and domain databases

    Gene3Di 2.40.37.10. 1 hit.
    3.20.20.10. 1 hit.
    HAMAPi MF_01201. Ala_racemase.
    InterProi IPR000821. Ala_racemase.
    IPR009006. Ala_racemase/Decarboxylase_C.
    IPR011079. Ala_racemase_C.
    IPR001608. Ala_racemase_N.
    IPR020622. Ala_racemase_pyridoxalP-BS.
    IPR029066. PLP-binding_barrel.
    [Graphical view ]
    Pfami PF00842. Ala_racemase_C. 1 hit.
    PF01168. Ala_racemase_N. 1 hit.
    [Graphical view ]
    PRINTSi PR00992. ALARACEMASE.
    SMARTi SM01005. Ala_racemase_C. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50621. SSF50621. 1 hit.
    SSF51419. SSF51419. 1 hit.
    TIGRFAMsi TIGR00492. alr. 1 hit.
    PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: WPP163Imported.

    Entry informationi

    Entry nameiD0KLP4_PECWW
    AccessioniPrimary (citable) accession number: D0KLP4
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2009
    Last sequence update: December 15, 2009
    Last modified: October 1, 2014
    This is version 41 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3