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D0KLP4 (D0KLP4_PECWW) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 32. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Alanine racemase RuleBase RU000608 HAMAP-Rule MF_01201
EC=5.1.1.1 RuleBase RU000608 HAMAP-Rule MF_01201
Gene names
Ordered Locus Names:Pecwa_3637
OrganismPectobacterium wasabiae (strain WPP163) [Complete proteome] [HAMAP] EMBL ACX89373.1
Taxonomic identifier561231 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Pectobacterium ›

Protein attributes

Sequence length359 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity. HAMAP-Rule MF_01201

Catalytic activity

L-alanine = D-alanine. RuleBase RU000608 HAMAP-Rule MF_01201 SAAS SAAS020622

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000608 HAMAP-Rule MF_01201 SAAS SAAS020622

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP-Rule MF_01201 SAAS SAAS020622

Sequence similarities

Belongs to the alanine racemase family. HAMAP-Rule MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site341Proton acceptor; specific for D-alanine By similarity HAMAP-Rule MF_01201
Active site2541Proton acceptor; specific for L-alanine By similarity HAMAP-Rule MF_01201
Binding site1291Substrate By similarity HAMAP-Rule MF_01201
Binding site3021Substrate; via amide nitrogen By similarity HAMAP-Rule MF_01201

Amino acid modifications

Modified residue341N6-(pyridoxal phosphate)lysine By similarity HAMAP-Rule MF_01201

Sequences

Sequence LengthMass (Da)Tools
D0KLP4 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: D13BCE5F15169B84

FASTA35938,876
        10         20         30         40         50         60 
MKTATAVISR RALRHNLQRI RQLAPGSQVV AVVKANAYGH GMIESAHTFC DADCYGVARL 

        70         80         90        100        110        120 
SEALALRAAG ITKPIVLLEG FFSADDLPLL AEHQLETAVH SPEQLAALEQ ATLPQPLRVW 

       130        140        150        160        170        180 
MKLDTGMHRL GVLPEQADAF WQRLTECRNV VQPVNIMSHF CRADEPEAGT TERQLACFDA 

       190        200        210        220        230        240 
FTQGKPGAQS IAASGGILLW PQAHRDRVRP GIILYGVSPL DNEDAAHFGF QPAMTFTSHL 

       250        260        270        280        290        300 
IAVREHKAGE AVGYGSTWTS PRDTRLGVVA VGYGDGYPRC APAGTPVLIN GREVPLSGRV 

       310        320        330        340        350 
SMDMITIDLG PDAQDKVGDE AILWGPALSV ERIAAHTGVS AYELITRLTQ RATLEYTDN

« Hide

References

[1]"Complete sequence of Pectobacterium wasabiae WPP163."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Balakrishnan V., Glasner J., Perna N.T.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WPP163.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001790 Genomic DNA. Translation: ACX89373.1.
RefSeqYP_003260980.1. NC_013421.1.

3D structure databases

ProteinModelPortalD0KLP4.
ModBaseSearch...

Protein-protein interaction databases

STRING561231.Pecwa_3637.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACX89373; ACX89373; Pecwa_3637.
GeneID8532063.
KEGGpwa:Pecwa_3637.
PATRIC32281562. VBIPecWas23660_3576.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHOG000031446.
KOK01775.
OMAHQLETAV.

Enzyme and pathway databases

BioCycPWAS561231:GHO0-3714-MONOMER.
UniPathwayUPA00042; UER00497.

Family and domain databases

Gene3D2.40.37.10. 1 hit.
HAMAPMF_01201. Ala_racemase.
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
[Graphical view]
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. alr. 1 hit.
PROSITEPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0KLP4_PECWW
AccessionPrimary (citable) accession number: D0KLP4
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: May 29, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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