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D0KIF9

- D0KIF9_PECWW

UniProt

D0KIF9 - D0KIF9_PECWW

Protein

NAD kinase

Gene

nadK

Organism
Pectobacterium wasabiae (strain WPP163)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 34 (01 Oct 2014)
      Sequence version 1 (15 Dec 2009)
      Previous versions | rss
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    Functioni

    Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.UniRule annotation

    Catalytic activityi

    ATP + NAD+ = ADP + NADP+.UniRule annotationSAAS annotation

    Cofactori

    Divalent metal ions.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei79 – 791Proton acceptorUniRule annotation
    Binding sitei164 – 1641NADUniRule annotation
    Binding sitei181 – 1811NADUniRule annotation
    Binding sitei183 – 1831NADUniRule annotation
    Binding sitei253 – 2531NADUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi79 – 802NADUniRule annotation
    Nucleotide bindingi153 – 1542NADUniRule annotation
    Nucleotide bindingi194 – 1996NADUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. metal ion binding Source: UniProtKB-HAMAP
    3. NAD+ kinase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. NAD metabolic process Source: InterPro
    2. NADP biosynthetic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    KinaseUniRule annotationSAAS annotationImported, Transferase

    Keywords - Ligandi

    ATP-bindingUniRule annotationSAAS annotation, NADUniRule annotationSAAS annotation, NADPUniRule annotationSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciPWAS561231:GHO0-989-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NAD kinaseUniRule annotation (EC:2.7.1.23UniRule annotation)
    Alternative name(s):
    ATP-dependent NAD kinaseUniRule annotation
    Gene namesi
    Name:nadKUniRule annotation
    Ordered Locus Names:Pecwa_0964Imported
    OrganismiPectobacterium wasabiae (strain WPP163)Imported
    Taxonomic identifieri561231 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium
    ProteomesiUP000000315: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Protein-protein interaction databases

    STRINGi561231.Pecwa_0964.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NAD kinase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0061.
    HOGENOMiHOG000227221.
    KOiK00858.
    OMAiTHEMLYH.
    OrthoDBiEOG6PZXDR.

    Family and domain databases

    Gene3Di2.60.200.30. 1 hit.
    3.40.50.10330. 1 hit.
    HAMAPiMF_00361. NAD_kinase.
    InterProiIPR017438. ATP-NAD_kinase_dom_1.
    IPR016064. ATP-NAD_kinase_PpnK-typ.
    IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
    IPR002504. PolyP/ATP_NADK.
    [Graphical view]
    PANTHERiPTHR20275. PTHR20275. 1 hit.
    PfamiPF01513. NAD_kinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF111331. SSF111331. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    D0KIF9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNTPLTMNRP FNCIGIVGHP RHPTALATHE MLYHWLTEKG YSVLIEQQIA    50
    RELNLKNAPT GSLADIGQQA DLAVVVGGDG NMLGAARVLS RYDIKVIGVN 100
    RGNLGFLTDL DPDHAQQQLS DVLDGHYLSE QRFMLEAHVC RANQPDSIST 150
    AINEVVLHPG KVAHMIEFEV YIDDKFAFSQ RSDGLIIATP TGSTAYSLSA 200
    GGPILTPSLE AIALVPMFPH TLSARPLVIN SSSTIRLKFS CITNDLEISC 250
    DSQIALPVQE GEEVLIRRSE HHLNLIHPKN YSYFNTLSSK LGWSKKLF 298
    Length:298
    Mass (Da):32,793
    Last modified:December 15, 2009 - v1
    Checksum:i717EC4F6DB0488B5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001790 Genomic DNA. Translation: ACX86781.1.
    RefSeqiYP_003258388.1. NC_013421.1.

    Genome annotation databases

    EnsemblBacteriaiACX86781; ACX86781; Pecwa_0964.
    GeneIDi8529338.
    KEGGipwa:Pecwa_0964.
    PATRICi32276116. VBIPecWas23660_0905.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP001790 Genomic DNA. Translation: ACX86781.1 .
    RefSeqi YP_003258388.1. NC_013421.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 561231.Pecwa_0964.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ACX86781 ; ACX86781 ; Pecwa_0964 .
    GeneIDi 8529338.
    KEGGi pwa:Pecwa_0964.
    PATRICi 32276116. VBIPecWas23660_0905.

    Phylogenomic databases

    eggNOGi COG0061.
    HOGENOMi HOG000227221.
    KOi K00858.
    OMAi THEMLYH.
    OrthoDBi EOG6PZXDR.

    Enzyme and pathway databases

    BioCyci PWAS561231:GHO0-989-MONOMER.

    Family and domain databases

    Gene3Di 2.60.200.30. 1 hit.
    3.40.50.10330. 1 hit.
    HAMAPi MF_00361. NAD_kinase.
    InterProi IPR017438. ATP-NAD_kinase_dom_1.
    IPR016064. ATP-NAD_kinase_PpnK-typ.
    IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
    IPR002504. PolyP/ATP_NADK.
    [Graphical view ]
    PANTHERi PTHR20275. PTHR20275. 1 hit.
    Pfami PF01513. NAD_kinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF111331. SSF111331. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: WPP163Imported.

    Entry informationi

    Entry nameiD0KIF9_PECWW
    AccessioniPrimary (citable) accession number: D0KIF9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 15, 2009
    Last sequence update: December 15, 2009
    Last modified: October 1, 2014
    This is version 34 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3