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D0KIF9 (D0KIF9_PECWW) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
NAD kinase HAMAP-Rule MF_00361

EC=2.7.1.23 HAMAP-Rule MF_00361
Alternative name(s):
ATP-dependent NAD kinase HAMAP-Rule MF_00361
Gene names
Name:nadK HAMAP-Rule MF_00361
Ordered Locus Names:Pecwa_0964 EMBL ACX86781.1
OrganismPectobacterium wasabiae (strain WPP163) [Complete proteome] [HAMAP] EMBL ACX86781.1
Taxonomic identifier561231 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaePectobacterium

Protein attributes

Sequence length298 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP By similarity. HAMAP-Rule MF_00361

Catalytic activity

ATP + NAD+ = ADP + NADP+. HAMAP-Rule MF_00361 SAAS SAAS002504

Cofactor

Divalent metal ions By similarity. HAMAP-Rule MF_00361

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00361 SAAS SAAS002504.

Sequence similarities

Belongs to the NAD kinase family. HAMAP-Rule MF_00361

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding79 – 802NAD By similarity HAMAP-Rule MF_00361
Nucleotide binding153 – 1542NAD By similarity HAMAP-Rule MF_00361
Nucleotide binding194 – 1996NAD By similarity HAMAP-Rule MF_00361

Sites

Active site791Proton acceptor By similarity HAMAP-Rule MF_00361
Binding site1641NAD By similarity HAMAP-Rule MF_00361
Binding site1811NAD By similarity HAMAP-Rule MF_00361
Binding site1831NAD By similarity HAMAP-Rule MF_00361
Binding site2531NAD By similarity HAMAP-Rule MF_00361

Sequences

Sequence LengthMass (Da)Tools
D0KIF9 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: 717EC4F6DB0488B5

FASTA29832,793
        10         20         30         40         50         60 
MNTPLTMNRP FNCIGIVGHP RHPTALATHE MLYHWLTEKG YSVLIEQQIA RELNLKNAPT 

        70         80         90        100        110        120 
GSLADIGQQA DLAVVVGGDG NMLGAARVLS RYDIKVIGVN RGNLGFLTDL DPDHAQQQLS 

       130        140        150        160        170        180 
DVLDGHYLSE QRFMLEAHVC RANQPDSIST AINEVVLHPG KVAHMIEFEV YIDDKFAFSQ 

       190        200        210        220        230        240 
RSDGLIIATP TGSTAYSLSA GGPILTPSLE AIALVPMFPH TLSARPLVIN SSSTIRLKFS 

       250        260        270        280        290 
CITNDLEISC DSQIALPVQE GEEVLIRRSE HHLNLIHPKN YSYFNTLSSK LGWSKKLF 

« Hide

References

[1]"Complete sequence of Pectobacterium wasabiae WPP163."
US DOE Joint Genome Institute
Lucas S., Copeland A., Lapidus A., Glavina del Rio T., Tice H., Bruce D., Goodwin L., Pitluck S., Chertkov O., Brettin T., Detter J.C., Han C., Larimer F., Land M., Hauser L., Kyrpides N., Ovchinnikova G., Balakrishnan V., Glasner J., Perna N.T.
Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WPP163 EMBL ACX86781.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001790 Genomic DNA. Translation: ACX86781.1.
RefSeqYP_003258388.1. NC_013421.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING561231.Pecwa_0964.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACX86781; ACX86781; Pecwa_0964.
GeneID8529338.
KEGGpwa:Pecwa_0964.
PATRIC32276116. VBIPecWas23660_0905.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0061.
HOGENOMHOG000227221.
KOK00858.
OMATHEMLYH.
OrthoDBEOG6PZXDR.

Enzyme and pathway databases

BioCycPWAS561231:GHO0-989-MONOMER.

Family and domain databases

Gene3D2.60.200.30. 1 hit.
3.40.50.10330. 1 hit.
HAMAPMF_00361. NAD_kinase.
InterProIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR017437. ATP-NAD_kinase_PpnK-typ_all-b.
IPR002504. PolyP/ATP_NADK.
[Graphical view]
PANTHERPTHR20275. PTHR20275. 1 hit.
PfamPF01513. NAD_kinase. 1 hit.
[Graphical view]
SUPFAMSSF111331. SSF111331. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD0KIF9_PECWW
AccessionPrimary (citable) accession number: D0KIF9
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: July 9, 2014
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)