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Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Pectobacterium parmentieri (strain WPP163) (Pectobacterium wasabiae (strain WPP163))
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotationSAAS annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotationSAAS annotation

Pathwayi: NAD(+) biosynthesis

This protein is involved in step 1 of the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate.UniRule annotationSAAS annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Nicotinate phosphoribosyltransferase (pncB)
This subpathway is part of the pathway NAD(+) biosynthesis, which is itself part of Cofactor biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes nicotinate D-ribonucleotide from nicotinate, the pathway NAD(+) biosynthesis and in Cofactor biosynthesis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferaseImported, LigaseUniRule annotationSAAS annotationImported, Transferase
Biological processPyridine nucleotide biosynthesisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotationSAAS annotation (EC:6.3.4.21UniRule annotationSAAS annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotation
Ordered Locus Names:Pecwa_2058Imported
OrganismiPectobacterium parmentieri (strain WPP163) (Pectobacterium wasabiae (strain WPP163))Imported
Taxonomic identifieri561231 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesPectobacteriaceaePectobacterium
Proteomesi
  • UP000000315 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi561231.Pecwa_2058.

Structurei

3D structure databases

ProteinModelPortaliD0KBT5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4107RH7. Bacteria.
COG1488. LUCA.
HOGENOMiHOG000284928.
KOiK00763.
OMAiKLTMQCA.
OrthoDBiPOG091H0197.

Family and domain databases

HAMAPiMF_00570. NAPRTase. 1 hit.
InterProiView protein in InterPro
IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR036068. Nicotinate_pribotase_like_C.
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiView protein in Pfam
PF04095. NAPRTase. 1 hit.
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

D0KBT5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTLHTSPILH SLLDTDAYKL HMQQAVYHHY YHVDVAAEFR CRGDELLGVY
60 70 80 90 100
ADEIAHQVDL MRFLSLSDDE FTYLSSLPFF QQDYLHWLRD FRFNPQQVSI
110 120 130 140 150
KNNAGKLDIR ITGPWREVIL WEVPLLAVIS EVVHRHRSSD VTTKQALAQL
160 170 180 190 200
SASLDNFRQN SKDVDLSRFK LMDFGTRRRF SRDVQQTIVT TLQADFPYLI
210 220 230 240 250
GTSNYDLARR LGITPVGTQA HEWFQAHQQI SPTLANSQRA ALQMWLHEYP
260 270 280 290 300
AHLGIALTDC ITMDAFLRDF DLPFAEAYQG LRHDSGDPVD WGEKAIAHYQ
310 320 330 340 350
HLNIDPMSKT LVFSDNLNLD KALALYRHFG QRVNLVFGMG TRLTCDIPSV
360 370 380 390 400
KPLNIVIKLV ECNGKPVAKL SDSPGKTICQ DQNFVCELRK AFDLPRVKKA

S
Length:401
Mass (Da):45,929
Last modified:December 15, 2009 - v1
Checksum:i2F4CD7C6B4FDCB4A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001790 Genomic DNA. Translation: ACX87837.1.
RefSeqiWP_014699712.1. NC_013421.1.

Genome annotation databases

EnsemblBacteriaiACX87837; ACX87837; Pecwa_2058.
KEGGipwa:Pecwa_2058.

Similar proteinsi

Entry informationi

Entry nameiD0KBT5_PECPW
AccessioniPrimary (citable) accession number: D0KBT5
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: October 25, 2017
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported