D0K9U7 (D0K9U7_STAAD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Fructose-bisphosphate aldolase class 1 HAMAP MF_00729
EC=4.1.2.13 HAMAP MF_00729

Alternative name(s):
Fructose-biphosphate aldolase class I HAMAP MF_00729

Gene names

Name:	fdaB EMBL ACY12502.1
Synonyms:	fda HAMAP MF_00729
Ordered Locus Names:	SAAV_2672

Organism

Staphylococcus aureus (strain ED98) [Complete proteome] [HAMAP]

Taxonomic identifier

681288 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	296 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate. HAMAP MF_00729
Pathway	Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4. HAMAP MF_00729
Sequence similarities	Belongs to the class I fructose-bisphosphate aldolase family. HAMAP MF_00729

Ontologies

Keywords
Biological process	Glycolysis HAMAP MF_00729
Ligand	Schiff base HAMAP MF_00729
Molecular function	Lyase HAMAP MF_00729
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular function	fructose-bisphosphate aldolase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	175	1	Proton acceptor By similarity HAMAP MF_00729
	Active site	212	1	Schiff-base intermediate with dihydroxyacetone-P By similarity HAMAP MF_00729

Sequences

	Sequence		Length	Mass (Da)
	D0K9U7 [UniParc]. Last modified December 15, 2009. Version 1. Checksum: D63B1A3C7646725B	FASTA	296	33,042
	10 20 30 40 50 60 MNKEQLEKMK NGKGFIAALD QSGGSTPKAL KEYGVNEDQY SNEDEMFQLV HDMRTRVVTS 70 80 90 100 110 120 PSFSPDKILG AILFEQTMDR EVEGKYTADY LADKGVVPFL KVDKGLAEEQ NGVQLMKPID 130 140 150 160 170 180 NLDSLLDRAN ERHIFGTKMR SNILELNEQG IKDVVEQQFE VAKQIIAKGL VPIIEPEVNI 190 200 210 220 230 240 NAKDKAEIEK VLKAELKKGL DSLNADQLVM LKLTIPTEPN LYKELAEHPN VVRVVVLSGG 250 260 270 280 290 YSREKANELL KDNDELIASF SRALASDLRA DQSKEEFDKA LGDAVESIYD ASVNKN

References

[1]

"Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus." Lowder B.V., Guinane C.M., Ben Zakour N.L., Weinert L.A., Conway-Morris A., Cartwright R.A., Simpson A.J., Rambaut A., Nubel U., Fitzgerald J.R. Proc. Natl. Acad. Sci. U.S.A. 106:19545-19550(2009) [PubMed: 19884497] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001781 Genomic DNA. Translation: ACY12502.1.
RefSeq	YP_003283508.1. NC_013450.1.
3D structure databases
ProteinModelPortal	D0K9U7.
SMR	D0K9U7. Positions 1-294.
ModBase	Search...
Protein-protein interaction databases
STRING	D0K9U7.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000055988; EBSTAP00000053501; EBSTAG00000057483.
GeneID	8615406.
GenomeReviews	Gene locus SAAV_2672 in contig CP001781_GR.
KEGG	sad:SAAV_2672.
PATRIC	32449432. VBIStaAur139507_2638.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000024908.
OMA	GTKMRSV.
Family and domain databases
HAMAP	MF_00729. FBP_aldolase_1. [Tree]
InterPro	IPR000741. Aldolase_I. IPR013785. Aldolase_TIM. IPR023014. FBP_aldolase_I_bac. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01623.
Pfam	PF00274. Glycolytic. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D0K9U7_STAAD

Accession

Primary (citable) accession number: D0K9U7

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2009
Last sequence update:	December 15, 2009
Last modified:	December 14, 2011
This is version 15 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)