D0K6G9 (D0K6G9_STAAD) Unreviewed, UniProtKB/TrEMBL
Last modified
December 14, 2011.
Version 18.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: NH(3)-dependent NAD(+) synthetase HAMAP MF_00193 RuleBase RU003812 EC=6.3.1.5 HAMAP MF_00193 RuleBase RU003812 | ||||
| Gene names |
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| Organism | Staphylococcus aureus (strain ED98) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 681288 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Staphylococcus |
Protein attributes
| Sequence length | 273 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+. HAMAP MF_00193 RuleBase RU003812 SAAS SAAS003694 |
| Pathway | Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1. HAMAP MF_00193 SAAS SAAS003694 RuleBase RU004252 |
| Sequence similarities | Belongs to the NAD synthetase family. HAMAP MF_00193 RuleBase RU003811 |
Ontologies
| Keywords | |
|---|---|
| Ligand | ATP-binding SAAS SAAS003694 HAMAP MF_00193 RuleBase RU003811 NAD HAMAP MF_00193 SAAS SAAS003694 RuleBase RU003811 Nucleotide-binding |
| Molecular function | Ligase HAMAP MF_00193 SAAS SAAS003694 RuleBase RU003811 |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | NAD biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Molecular function | ATP binding Inferred from electronic annotation. Source: HAMAP NAD+ synthase (glutamine-hydrolyzing) activityInferred from electronic annotation. Source: InterPro NAD+ synthase activityInferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Regions | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Nucleotide binding | 47 – 54 | 8 | ATP By similarity HAMAP MF_00193 | ||||||
Sites | |||||||||
| Active site | 49 | 1 | By similarity HAMAP MF_00193 | ||||||
Sequences
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References
| [1] | "Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus." Lowder B.V., Guinane C.M., Ben Zakour N.L., Weinert L.A., Conway-Morris A., Cartwright R.A., Simpson A.J., Rambaut A., Nubel U., Fitzgerald J.R. Proc. Natl. Acad. Sci. U.S.A. 106:19545-19550(2009) [PubMed: 19884497] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP001781 Genomic DNA. Translation: ACY11829.1. |
| RefSeq | YP_003282835.1. NC_013450.1. |
3D structure databases | |
| ProteinModelPortal | D0K6G9. |
| SMR | D0K6G9. Positions 4-268. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | D0K6G9. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBSTAT00000056606; EBSTAP00000054416; EBSTAG00000055146. |
| GeneID | 8614717. |
| GenomeReviews | Gene locus SAAV_1979 in contig CP001781_GR. |
| KEGG | sad:SAAV_1979. |
| PATRIC | 32448026. VBIStaAur139507_1949. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| GeneTree | EBGT00050000025036. |
| OMA | IAQYEIA. |
Family and domain databases | |
| HAMAP | MF_00193. NadE. [Tree] |
| InterPro | IPR022310. NAD/GMP_synthase. IPR003694. NAD_synthase. IPR022926. NH(3)-dep_NAD(+)_synth. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view] |
| Gene3D | G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit. |
| KO | K01916. |
| Pfam | PF02540. NAD_synthase. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00552. NadE. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | D0K6G9_STAAD | ||||||||
| Accession | Primary (citable) accession number: D0K6G9 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

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