D0K5V2 (D0K5V2_STAAD) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Acetate kinase HAMAP MF_00020
EC=2.7.2.1 HAMAP MF_00020

Alternative name(s):
Acetokinase HAMAP MF_00020

Gene names

Name:	ackA HAMAP MF_00020 EMBL ACY11612.1
Ordered Locus Names:	SAAV_1721

Organism

Staphylococcus aureus (strain ED98) [Complete proteome] [HAMAP]

Taxonomic identifier

681288 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Staphylococcus

Protein attributes

Sequence length	400 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + acetate = ADP + acetyl phosphate. HAMAP MF_00020 SAAS SAAS000890 ATP + propanoate = ADP + propanoyl phosphate. HAMAP MF_00020 SAAS SAAS000890
Pathway	Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2. HAMAP MF_00020
Subcellular location	Cytoplasm By similarity HAMAP MF_00020.
Sequence similarities	Belongs to the acetokinase family. HAMAP MF_00020 RuleBase RU003835

Ontologies

Keywords
Cellular component	Cytoplasm HAMAP MF_00020 SAAS SAAS000890
Ligand	ATP-binding HAMAP MF_00020 SAAS SAAS000890 Nucleotide-binding
Molecular function	Kinase HAMAP MF_00020 SAAS SAAS000890 RuleBase RU003835 EMBL ACY11612.1 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	organic acid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW acetate kinase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	D0K5V2 [UniParc]. Last modified December 15, 2009. Version 1. Checksum: C792C2F1B7E21CAE	FASTA	400	44,057
	10 20 30 40 50 60 MSKLILAINA GSSSLKFQLI RMPEEELVTK GLIERIGLKD SIFTIEVNGE KVKTVQDIKD 70 80 90 100 110 120 HVEAVDIMLD AFKAHNIIND INDIDGTGHR VVHGGEKFPE SVAITDEVEK EIEELSELAP 130 140 150 160 170 180 LHNPANLMGI RAFRKLLPNI PHVAIFDTAF HQTMPEKAYL YSLPYHYYKD YGIRKYGFHG 190 200 210 220 230 240 TSHKFVSQRA AEMLDKPIED LRIISCHIGN GASIAAIDGG KSIDTSMGFT PLAGVTMGTR 250 260 270 280 290 300 SGNIDPALIP FIMEKTGKTA EQVLEILNKE SGLLGLSGTS SDLRDLSEEA ESGKARSQMA 310 320 330 340 350 360 LDVFASKIHK YIGSYAARMH GVDVIVFTAG IGENSVEIRA KVLEGLEFMG VYWDPKKNEN 370 380 390 400 LLRGKEGFIN YPHSPVKVVV IPTDEESMIA RDVMTFGGLK

References

[1]

"Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus." Lowder B.V., Guinane C.M., Ben Zakour N.L., Weinert L.A., Conway-Morris A., Cartwright R.A., Simpson A.J., Rambaut A., Nubel U., Fitzgerald J.R. Proc. Natl. Acad. Sci. U.S.A. 106:19545-19550(2009) [PubMed: 19884497] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP001781 Genomic DNA. Translation: ACY11612.1.
RefSeq	YP_003282618.1. NC_013450.1.
3D structure databases
ProteinModelPortal	D0K5V2.
SMR	D0K5V2. Positions 5-396.
ModBase	Search...
Protein-protein interaction databases
STRING	D0K5V2.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTAT00000055765; EBSTAP00000054632; EBSTAG00000057538.
GeneID	8614459.
GenomeReviews	Gene locus SAAV_1721 in contig CP001781_GR.
KEGG	sad:SAAV_1721.
PATRIC	32447495. VBIStaAur139507_1723.
Organism-specific databases
CMR	Search...
Phylogenomic databases
GeneTree	EBGT00050000024640.
OMA	LIDMTNE.
Family and domain databases
HAMAP	MF_00020. Acetate_kinase. [Tree]
InterPro	IPR004372. Ac/Proprionate_kinase. IPR000890. Aliphatic_acid_kin_short-chain. IPR023865. Aliphatic_acid_kinase_CS. [Graphical view]
KO	K00925.
PANTHER	PTHR21060. Acetate_kin. 1 hit.
Pfam	PF00871. Acetate_kinase. 1 hit. [Graphical view]
PIRSF	PIRSF000722. Acetate_prop_kin. 1 hit.
PRINTS	PR00471. ACETATEKNASE.
TIGRFAMs	TIGR00016. AckA. 1 hit.
PROSITE	PS01075. ACETATE_KINASE_1. 1 hit. PS01076. ACETATE_KINASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

D0K5V2_STAAD

Accession

Primary (citable) accession number: D0K5V2

Entry history

Integrated into UniProtKB/TrEMBL:	December 15, 2009
Last sequence update:	December 15, 2009
Last modified:	January 25, 2012
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)