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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Yersinia pestis (strain D106004)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotationSAAS annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei111 – 1111UniRule annotation
Active sitei519 – 5191UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Biological processi

Carbon dioxide fixationUniRule annotationSAAS annotation

Keywords - Ligandi

MagnesiumUniRule annotationSAAS annotation, PyruvateImported

Enzyme and pathway databases

BioCyciYPES637382:GLMX-3544-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:YPD4_3461Imported
OrganismiYersinia pestis (strain D106004)Imported
Taxonomic identifieri637382 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeYersinia
ProteomesiUP000000285 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0JK55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGEHILDRVE TIRKLSKSSR AGNEASRQEL LTTLQNLSND ELLPVARAFS
60 70 80 90 100
QFLNLTNTAE QYHSISPHGE AASNPEALAQ LFTRLKDKKL SDQDMRSAVD
110 120 130 140 150
DLSIELVLTA HPTEITRRTL IHKLVEVNTC LSQLDHNDLA DYERNKIMRR
160 170 180 190 200
LRQLVAQSWH TDEIRKLRPS PVDEAKWGFA VVENSLWEGV PAFLREFNEQ
210 220 230 240 250
LENSLDYRLP VEAVPIRFTS WMGGDRDGNP NVTAEITRHV LLLSRWKATD
260 270 280 290 300
LFLRDIQVLV SELSMSECTP ELRELAGGEE VLEPYRQLMK NVRTQLTNTQ
310 320 330 340 350
AYLEARLKGE RVLPPHDLLV SNDQLWEPLY ACYQSLKACG MEIIANGQLL
360 370 380 390 400
DTLRRVRCFG VPLVRIDVRQ ESTRHTDAIA ELTRYLGLGD YESWSESDKQ
410 420 430 440 450
AFLVRELNSK RPLVPLKWEP SAETQEVLET CRVIAEAPQG SIAAYVISMA
460 470 480 490 500
KVPSDVLAVH LLLKEAGCPF TLPVAPLFET LDDLNNADDV MTQLLGIDWY
510 520 530 540 550
RGLIQGKQMV MIGYSDSAKD AGVMAASWAQ YRAQDALIKT CEKAGITLTL
560 570 580 590 600
FHGRGGSIGR GGAPAHAALL SQPPGSLKGG LRVTEQGEMI RFKFGLPEVT
610 620 630 640 650
ISSLALYAGA ILEANLLPPP EPKKEWIEVM DLLSDASCDM YRSYVRENPE
660 670 680 690 700
FVRYFRAATP ELELGKLPLG SRPAKRRPDG GVESLRAIPW IFAWTQNRLM
710 720 730 740 750
LPAWLGAGAG LQRAIDAGKQ DVLATMCRDW PFFSTRIGML EMVFAKADLW
760 770 780 790 800
LAEYYDQRLV DKSLWPLGQQ LRDQLAADIK VVLAIANDDH LMADLPWIAE
810 820 830 840 850
SIALRNVYTD PLNVLQAELL HRSRQQEHPD ACVEQALMVT IAGVAAGMRN

TG
Length:852
Mass (Da):95,499
Last modified:December 14, 2009 - v1
Checksum:i247B134F809AC8FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001585 Genomic DNA. Translation: ACY60365.1.
RefSeqiYP_005506668.1. NC_017154.1.

Genome annotation databases

EnsemblBacteriaiACY60365; ACY60365; YPD4_3461.
GeneIDi12093385.
KEGGiypd:YPD4_3461.
PATRICi36761942. VBIYerPes77623_4585.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001585 Genomic DNA. Translation: ACY60365.1.
RefSeqiYP_005506668.1. NC_017154.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACY60365; ACY60365; YPD4_3461.
GeneIDi12093385.
KEGGiypd:YPD4_3461.
PATRICi36761942. VBIYerPes77623_4585.

Phylogenomic databases

HOGENOMiHOG000238648.
KOiK01595.
OMAiCGMGVIA.

Enzyme and pathway databases

BioCyciYPES637382:GLMX-3544-MONOMER.

Family and domain databases

HAMAPiMF_00595. PEPcase_type1.
InterProiIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSiPR00150. PEPCARBXLASE.
SUPFAMiSSF51621. SSF51621. 1 hit.
PROSITEiPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Spatial variation of Yersinia pestis from Yunnan Province of China."
    Zhang Z., Hai R., Song Z., Xia L., Liang Y., Cai H., Liang Y., Shen X., Zhang E., Xu J., Yu D., Yu X.J.
    Am. J. Trop. Med. Hyg. 81:714-717(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: D106004Imported.

Entry informationi

Entry nameiD0JK55_YERPD
AccessioniPrimary (citable) accession number: D0JK55
Entry historyi
Integrated into UniProtKB/TrEMBL: December 14, 2009
Last sequence update: December 14, 2009
Last modified: March 3, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.