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D0JBF3

- D0JBF3_BLASB

UniProt

D0JBF3 - D0JBF3_BLASB

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Protein

Phosphoribosylaminoimidazole-succinocarboxamide synthase

Gene

purC

Organism
Blattabacterium sp. subsp. Blattella germanica (strain Bge) (Blattella germanica symbiotic bacterium)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate = ADP + phosphate + (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate.UniRule annotationSAAS annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylaminoimidazolesuccinocarboxamide synthase activity Source: UniProtKB-EC

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

LigaseUniRule annotationSAAS annotation

Keywords - Biological processi

Purine biosynthesisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSP331104:GH6K-484-MONOMER.
UniPathwayiUPA00074; UER00131.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylaminoimidazole-succinocarboxamide synthaseUniRule annotationSAAS annotation (EC:6.3.2.6UniRule annotationSAAS annotation)
Alternative name(s):
SAICAR synthetaseUniRule annotation
Gene namesi
Name:purCUniRule annotationImported
Ordered Locus Names:BLBBGE_484Imported
OrganismiBlattabacterium sp. subsp. Blattella germanica (strain Bge) (Blattella germanica symbiotic bacterium)Imported
Taxonomic identifieri331104 [NCBI]
Taxonomic lineageiBacteriaBacteroidetesFlavobacteriiaFlavobacterialesBlattabacteriaceaeBlattabacterium
ProteomesiUP000002625: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi331104.BLBBGE_484.

Structurei

3D structure databases

ProteinModelPortaliD0JBF3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SAICAR synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0152.
HOGENOMiHOG000082629.
KOiK01923.
OMAiVQYFKDD.
OrthoDBiEOG62C9HN.

Family and domain databases

Gene3Di3.30.470.20. 1 hit.
HAMAPiMF_00137. SAICAR_synth.
InterProiIPR013816. ATP_grasp_subdomain_2.
IPR028923. SAICAR_synt/ADE2_N.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view]
PfamiPF01259. SAICAR_synt. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00081. purC. 1 hit.
PROSITEiPS01057. SAICAR_SYNTHETASE_1. 1 hit.
PS01058. SAICAR_SYNTHETASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

D0JBF3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSFVIKKNLL SEGKTKKIYT TNNSLEVLIH YKDSITALDG SKNQFLQDKG
60 70 80 90 100
ILNNEISTLI FKFINSCGIK THFIRKINNR EQLCYKVDII PLEFVVRNIV
110 120 130 140 150
AGSMSKRLNI QEGIRLLNPI FEIFYKNDKL KDPLINDHHA VFLGIISYEE
160 170 180 190 200
INAIYRIVSN VNNILKKYFL DKNIILVDFK IEFGKNDQND ILLSDEISPD
210 220 230 240
TCRFWDKKTM KKLDKDPFRI GLKEKEEVLD IYMEILKRLN VR
Length:242
Mass (Da):28,366
Last modified:December 15, 2009 - v1
Checksum:i127ECE303EECB463
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001487 Genomic DNA. Translation: ACY40491.1.
RefSeqiYP_003284101.1. NC_013454.1.

Genome annotation databases

EnsemblBacteriaiACY40491; ACY40491; BLBBGE_484.
GeneIDi8555043.
KEGGibbl:BLBBGE_484.
PATRICi31959608. VBIBlaSp132937_0464.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001487 Genomic DNA. Translation: ACY40491.1 .
RefSeqi YP_003284101.1. NC_013454.1.

3D structure databases

ProteinModelPortali D0JBF3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 331104.BLBBGE_484.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ACY40491 ; ACY40491 ; BLBBGE_484 .
GeneIDi 8555043.
KEGGi bbl:BLBBGE_484.
PATRICi 31959608. VBIBlaSp132937_0464.

Phylogenomic databases

eggNOGi COG0152.
HOGENOMi HOG000082629.
KOi K01923.
OMAi VQYFKDD.
OrthoDBi EOG62C9HN.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00131 .
BioCyci BSP331104:GH6K-484-MONOMER.

Family and domain databases

Gene3Di 3.30.470.20. 1 hit.
HAMAPi MF_00137. SAICAR_synth.
InterProi IPR013816. ATP_grasp_subdomain_2.
IPR028923. SAICAR_synt/ADE2_N.
IPR001636. SAICAR_synth.
IPR018236. SAICAR_synthetase_CS.
[Graphical view ]
Pfami PF01259. SAICAR_synt. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00081. purC. 1 hit.
PROSITEi PS01057. SAICAR_SYNTHETASE_1. 1 hit.
PS01058. SAICAR_SYNTHETASE_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica."
    Lopez-Sanchez M.J., Neef A., Pereto J., Patino-Navarrete R., Pignatelli M., Latorre A., Moya A.
    PLoS Genet. 5:E1000721-E1000721(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: BgeImported.

Entry informationi

Entry nameiD0JBF3_BLASB
AccessioniPrimary (citable) accession number: D0JBF3
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: November 26, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3