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D0JAJ6 (D0JAJ6_BLASB) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 13. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha HAMAP MF_00823
Short name=ACCase subunit alpha HAMAP MF_00823
Short name=Acetyl-CoA carboxylase carboxyltransferase subunit alpha HAMAP MF_00823
EC=6.4.1.2 HAMAP MF_00823
Gene names
Name:accA HAMAP MF_00823 EMBL ACY40184.1
Ordered Locus Names:BLBBGE_154
OrganismBlattabacterium sp. subsp. Blattella germanica (strain Bge) (Blattella germanica symbiotic bacterium) [Complete proteome] [HAMAP]
Taxonomic identifier331104 [NCBI]
Taxonomic lineageBacteria › Bacteroidetes › Flavobacteriia › Flavobacteriales › Blattabacteriaceae › Blattabacterium

Protein attributes

Sequence length287 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO2 group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA By similarity. HAMAP MF_00823 SAAS SAAS011763

Catalytic activity

ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA. HAMAP MF_00823 SAAS SAAS011763

Pathway

Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1. HAMAP MF_00823 SAAS SAAS011763

Subunit structure

Acetyl-CoA carboxylase is an heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD) By similarity. HAMAP MF_00823 SAAS SAAS011763

Subcellular location

Cytoplasm By similarity HAMAP MF_00823 SAAS SAAS011763.

Sequence similarities

Belongs to the AccA family. HAMAP MF_00823

Sequences

Sequence LengthMass (Da)Tools
D0JAJ6 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: 64F52D01F330D826

FASTA28732,674
        10         20         30         40         50         60 
MEYLDFEKPI QEIKDQYLNC IMIEEKSGVD MKEVCSQLQS KLEKTIKKLH NNLTPWQRVQ 

        70         80         90        100        110        120 
LSRHPNRPYT LDYIQSITKK DSFIELHGDR HFGDDKAMVG GFGKIEDKTF MLIGTQKGKN 

       130        140        150        160        170        180 
TKDRQYRRFG MPNPEGYRKA LRLMKLAEKF RKPIITFIDT PGAFPGIEAE KRGQGEAIGK 

       190        200        210        220        230        240 
NIYEMMCLKV PIIVLIIGEG ASGGAMGIGI GDKVSMMENS WFSVISPESC STILWGKWDK 

       250        260        270        280 
KEKSAEALKL TAEDMYNLNL IDDIIKEPLG GAHFCPKKAY KLVKNKL

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References

[1]"Evolutionary convergence and nitrogen metabolism in Blattabacterium strain Bge, primary endosymbiont of the cockroach Blattella germanica."
Lopez-Sanchez M.J., Neef A., Pereto J., Patino-Navarrete R., Pignatelli M., Latorre A., Moya A.
PLoS Genet. 5:E1000721-E1000721(2009) [PubMed: 19911043] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP001487 Genomic DNA. Translation: ACY40184.1.
RefSeqYP_003283794.1. NC_013454.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGD0JAJ6.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID8554713.
GenomeReviewsGene locus BLBBGE_154 in contig CP001487_GR.
KEGGbbl:BLBBGE_154.
PATRIC31958942. VBIBlaSp132937_0150.

Organism-specific databases

CMRSearch...

Phylogenomic databases

OMAGRDTKDN.

Family and domain databases

HAMAPMF_00823. AcetylCoA_CT_alpha.
[Tree]
InterProIPR001095. Acetyl_CoA_COase_a_su.
IPR011763. COA_CT_C.
[Graphical view]
KOK01962.
PANTHERPTHR22855:SF3. Ac-CoA_carboxylA. 1 hit.
PfamPF03255. ACCA. 1 hit.
[Graphical view]
PRINTSPR01069. ACCCTRFRASEA.
TIGRFAMsTIGR00513. AccA. 1 hit.
PROSITEPS50989. COA_CT_CTER. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameD0JAJ6_BLASB
AccessionPrimary (citable) accession number: D0JAJ6
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: December 14, 2011
This is version 13 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info