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Protein

Phosphoenolpyruvate carboxylase

Gene

ppc

Organism
Comamonas testosteroni (strain CNB-2)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotationSAAS annotation

Cofactori

Mg2+UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei163UniRule annotation1
Active sitei605UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyaseUniRule annotationSAAS annotation
Biological processCarbon dioxide fixationUniRule annotationSAAS annotation
LigandMagnesiumUniRule annotationSAAS annotation, PyruvateImported

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotationSAAS annotation (EC:4.1.1.31UniRule annotationSAAS annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcUniRule annotation
Ordered Locus Names:CtCNB1_3531Imported
OrganismiComamonas testosteroni (strain CNB-2)Imported
Taxonomic identifieri688245 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeComamonas
Proteomesi
  • UP000002360 Componenti: Chromosome

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi688245.CtCNB1_3531

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiENOG4105CCA Bacteria
COG2352 LUCA
HOGENOMiHOG000238647
KOiK01595
OMAiPWVFGWT

Family and domain databases

HAMAPiMF_00595 PEPcase_type1, 1 hit
InterProiView protein in InterPro
IPR021135 PEP_COase
IPR022805 PEP_COase_bac/pln-type
IPR018129 PEP_COase_Lys_AS
IPR033129 PEPCASE_His_AS
IPR015813 Pyrv/PenolPyrv_Kinase-like_dom
PANTHERiPTHR30523 PTHR30523, 1 hit
PfamiView protein in Pfam
PF00311 PEPcase, 1 hit
PRINTSiPR00150 PEPCARBXLASE
SUPFAMiSSF51621 SSF51621, 1 hit
PROSITEiView protein in PROSITE
PS00781 PEPCASE_1, 1 hit
PS00393 PEPCASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

D0J463-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSARPKSAA HTDKHGDKPV RKTDKDLPLI EDIRLLGRIL GDVIREQEGG
60 70 80 90 100
PAYELVEQVR QLSVAFRRDA DEAADKALKK LLKGLSSDQT VSVIRAFTYF
110 120 130 140 150
SHLANLAEDR HHIRRRAVHE RAGNTQEGSI EVALARLRWA GISTATVVDT
160 170 180 190 200
LAKSFISPVL TAHPTEVQRQ SILTAERRIA QLLAERDDIL MRAQLYNSAK
210 220 230 240 250
DALTPRELTR VEAQLRACVA QLWQTRLLRH SKLTVADEIE NALSYYEATF
260 270 280 290 300
LQEIPKIYEQ LEQELGEKLP EQSFLRMGQW IGGDRDGNPF VTAESLELAL
310 320 330 340 350
SRQADVALRH YLREVHYLGG ELSLSANLVD ITPEMQALAD ASPDHNVHRS
360 370 380 390 400
DEPYRRALTG IYARLAATLK QLTGGEAARH AVAPQNAYAS ADAFLADLQI
410 420 430 440 450
IDDSLSRYHG DALAPQRLRP LMRAVRVFGF YLSTVDLRQS SDKHEEVVRE
460 470 480 490 500
LLSVAKVELD YSLLEEDAKC ALLVRLLEDA RPLRVMGGDY GDHTRSELAI
510 520 530 540 550
FETAKRLRER LGSEAIRHCI ISHTETVSDL LEVLLLQKEV GLLRGTLQDG
560 570 580 590 600
AQCDLIVVPL FETIEDLRNA APIMRRYYQL PGIAELVRKS GGEQDIMLGY
610 620 630 640 650
SDSNKDGGIF TSNWELYRAE IALVDLFDDL ADHYGIRLRM FHGRGGTVGR
660 670 680 690 700
GGGPSYQAIL AQPPGTVRGQ IRLTEQGEVI ASKYANPEIG RRNLETLVAA
710 720 730 740 750
TLEATLLQPT KPATKAFLEA AAFLSEASMA AYRALVYETP GFTNYFFSST
760 770 780 790 800
PIREIAELNI GSRPASRKAT QAIEDLRAIP WGFSWGQCRL TLPGWYGFGS
810 820 830 840 850
AIQAFIHRPG KDAKAQLALL QKMYRQWPFF RTLLSNMDMV LAKSDLNLAS
860 870 880 890 900
RYSELVTDTR LRRRIFGAIE AEWQSTVEAL NQITGDKQRL EHNSALARSI
910 920 930 940
RHRFPYIDPL NHLQVELVRR WRAGQTDDRV KNGIHLSING IAAGVRNTG
Length:949
Mass (Da):106,230
Last modified:December 15, 2009 - v1
Checksum:iCF74FACEF2D3136E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001220 Genomic DNA Translation: ACY34277.1
RefSeqiWP_012839366.1, NC_013446.2

Genome annotation databases

EnsemblBacteriaiACY34277; ACY34277; CtCNB1_3531
KEGGictt:CtCNB1_3531
PATRICifig|688245.4.peg.3751

Similar proteinsi

Entry informationi

Entry nameiD0J463_COMT2
AccessioniPrimary (citable) accession number: D0J463
Entry historyiIntegrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: March 28, 2018
This is version 60 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health