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D0IZE6 (D0IZE6_COMT2) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 26. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570

Short name=NAPRTase HAMAP-Rule MF_00570
EC=2.4.2.11 HAMAP-Rule MF_00570
Gene names
Name:pncB HAMAP-Rule MF_00570
Ordered Locus Names:CtCNB1_0650
OrganismComamonas testosteroni (strain CNB-2) [Complete proteome] [HAMAP]
Taxonomic identifier688245 [NCBI]
Taxonomic lineageBacteriaProteobacteriaBetaproteobacteriaBurkholderialesComamonadaceaeComamonas

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Beta-nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. HAMAP-Rule MF_00570 SAAS SAAS002638

Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. RuleBase RU003838

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. RuleBase RU003838 HAMAP-Rule MF_00570 SAAS SAAS002638

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00570 SAAS SAAS002638.

Sequence similarities

Belongs to the NAPRTase family. RuleBase RU003838 HAMAP-Rule MF_00570

Sequences

Sequence LengthMass (Da)Tools
D0IZE6 [UniParc].

Last modified December 15, 2009. Version 1.
Checksum: 9783C8DA267CCA6D

FASTA41647,617
        10         20         30         40         50         60 
MDKALAAHIF EKKNGMKPII TSLLDTDLYK FTMWQAMLHR HPQTEAEYEF VCRTPTAFPL 

        70         80         90        100        110        120 
AELLPEVERE LDALCSLRFD KGELDYLAGL RFMKSDFIDF LRIFQFQRAF IRAWAEGDRL 

       130        140        150        160        170        180 
HIVAKGPQVH VMGFEIYVLA IVNELYFRRF DADAALVEGR KRLQVKLAQL KHLAVEARLH 

       190        200        210        220        230        240 
NPFELFDFGV RRRFSGAWQR EVVQAFAQET AQWFKGTSNV LLARDLNLVP IGTMAHEYLQ 

       250        260        270        280        290        300 
TYQALGVRLR DFQVAALEDW VQEYRGDLGI ALTDTVGMDA FLADFDMYFA KLFDDLRHDS 

       310        320        330        340        350        360 
GDPFEWGEKA IAHYEKLRIA PQSKRLVFSD GLDLDTALAL YHRFADRIQC GFGIGTRLTN 

       370        380        390        400        410 
DMGLTTINIV MKLTHANGQP VAKISDSPGK TLCNDETYLA YLRQVFNIPE PAAKAA 

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References

[1]"The complete genome of Comamonas testosteroni reveals its genetic adaptations to changing environments."
Ma Y.F., Zhang Y., Zhang J.Y., Chen D.W., Zhu Y., Zheng H., Wang S.Y., Jiang C.Y., Zhao G.P., Liu S.J.
Appl. Environ. Microbiol. 75:6812-6819(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: CNB-2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP001220 Genomic DNA. Translation: ACY31396.1.
RefSeqYP_003276692.1. NC_013446.1.

3D structure databases

ProteinModelPortalD0IZE6.
ModBaseSearch...

Protein-protein interaction databases

STRING688245.CtCNB1_0650.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACY31396; ACY31396; CtCNB1_0650.
GeneID8563282.
KEGGctt:CtCNB1_0650.
PATRIC35262155. VBIComTes153857_0777.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.

Enzyme and pathway databases

BioCycCTES543891:GJCV-663-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR015977. Nic_PRibTrfase-like.
IPR007229. Nic_PRibTrfase-rel.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. Q_phspho_trans. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameD0IZE6_COMT2
AccessionPrimary (citable) accession number: D0IZE6
Entry history
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: May 29, 2013
This is version 26 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)