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Protein
Submitted name:

Angiotensin converting enzyme-like 3

Gene

Ace3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

CarboxypeptidaseUniRule annotation, Hydrolase, MetalloproteaseUniRule annotation, Protease

Keywords - Ligandi

Metal-bindingUniRule annotation, ZincUniRule annotation

Protein family/group databases

MEROPSiM02.971.

Names & Taxonomyi

Protein namesi
Submitted name:
Angiotensin converting enzyme-like 3Imported
Submitted name:
Protein Ace3Imported
Gene namesi
Name:Ace3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:3644400. Ace3.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei639 – 66022HelicalSequence analysisAdd
BLAST
Transmembranei700 – 72122HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • acrosomal vesicle Source: MGI
  • integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1717Sequence analysisAdd
BLAST
Chaini18 – 737720Sequence analysisPRO_5005907775Add
BLAST

Keywords - PTMi

GlycoproteinUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137762.

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase M2 family.UniRule annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410XPJ3. LUCA.
KOG3690. Eukaryota.
GeneTreeiENSGT00520000055576.
KOiK01283.
OMAiLYYDLAY.
OrthoDBiEOG76HQ13.

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.

Sequencei

Sequence statusi: Complete.

D0G895-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLPWALLLV LLSHRQLLPW LRTVGETSLN DFYSEAQAKL FLQFYEQTAQ
60 70 80 90 100
VVLNEFMEAT WNYVTNITKQ NQKNMLQKEA DRSQFMLYFS TRARMFRTDH
110 120 130 140 150
FLNQDVKRML RKLQNIDKSA LPTEDLLEYN RLLTYMETAY NRAEVCLDEG
160 170 180 190 200
PCLTLEPDLQ EIMATSRDQK ELLWAWQGWR DAVGRQLRPV FEDYVRLSNK
210 220 230 240 250
AAQYNGYKDM GALWRSKYES DTLEEDLEQL YKELQPLYLN LHAYVRRSLY
260 270 280 290 300
RYYGPELIDL RGPIPAHLLG NMWAQSWNNI LDLVLPYPTK APEDITAIMK
310 320 330 340 350
IQHWRPEKMF EEANLFFTSM GMLPAPPAFW IKSMMEKPAD GREVECHTSS
360 370 380 390 400
WNFYKFNDFR VKKCTEVTLE DLLSVFHQMG HIQYFLQYQN LSVIYQEGAS
410 420 430 440 450
PAFEEAVGSV IALSVSSHKY LLARGLLSQP HQDSEEEVNF LLGIALEKIA
460 470 480 490 500
FIPFSYLVDK FRWKIFDGTI SKITYNQEWW NFRLKYQGLC PPVPRSDDDF
510 520 530 540 550
DPGAKFHIPA NVPYIRYFLG LILQFQLHEA LCEASGHVGP LHQCDNYNSK
560 570 580 590 600
VAGKILGDLL KLGSSRPWRE VLQEVTGESN ISTKAFLTYF KPLMDWLVTE
610 620 630 640 650
NVKQGDTLGW PDFSCSFEEK ITSKVSFLGT DTEPEQAYLG QWVLLSMSFF
660 670 680 690 700
MLVLILALGF RLHYLEKQLL DEDTMILKTL PYSYFLGIAM EPHQAARKQW
710 720 730
LLLGLCCILM LCCIGLLIRI VTQNTENTPW MKNEGQS
Length:737
Mass (Da):85,874
Last modified:December 15, 2009 - v1
Checksum:i149363A9C6372A61
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596331 Genomic DNA. No translation available.
AB531024 mRNA. Translation: BAI48788.1.
RefSeqiNP_001094923.2. NM_001101453.2.
UniGeneiMm.296699.

Genome annotation databases

EnsembliENSMUST00000190995; ENSMUSP00000140827; ENSMUSG00000101605.
GeneIDi217246.
KEGGimmu:217246.
UCSCiuc011ygg.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596331 Genomic DNA. No translation available.
AB531024 mRNA. Translation: BAI48788.1.
RefSeqiNP_001094923.2. NM_001101453.2.
UniGeneiMm.296699.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000137762.

Protein family/group databases

MEROPSiM02.971.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000190995; ENSMUSP00000140827; ENSMUSG00000101605.
GeneIDi217246.
KEGGimmu:217246.
UCSCiuc011ygg.2. mouse.

Organism-specific databases

CTDi217246.
MGIiMGI:3644400. Ace3.

Phylogenomic databases

eggNOGiENOG410XPJ3. LUCA.
KOG3690. Eukaryota.
GeneTreeiENSGT00520000055576.
KOiK01283.
OMAiLYYDLAY.
OrthoDBiEOG76HQ13.

Miscellaneous databases

NextBioi375701.
SOURCEiSearch...

Family and domain databases

InterProiIPR001548. Peptidase_M2.
[Graphical view]
PANTHERiPTHR10514. PTHR10514. 1 hit.
PfamiPF01401. Peptidase_M2. 1 hit.
[Graphical view]
PRINTSiPR00791. PEPDIPTASEA.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. "ACE3."
    Inoue N., Okabe M.
    Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.
  3. Ensembl
    Submitted (SEP-2014) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiD0G895_MOUSE
AccessioniPrimary (citable) accession number: D0G895
Entry historyi
Integrated into UniProtKB/TrEMBL: December 15, 2009
Last sequence update: December 15, 2009
Last modified: January 20, 2016
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.